Iron in PDB 7o4i: Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble

All present enzymatic activity of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble:
2.7.7.6; 3.6.4.12;

The structure of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble also contains other interesting chemical elements:

Zinc	(Zn)	17 atoms
Fluorine	(F)	3 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Iron atom in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble (pdb code 7o4i). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble, PDB code: 7o4i:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:88.8 occ:1.00 FE1 0:SF4801 0.0 88.8 1.0 SG 0:CYS115 2.3 99.0 1.0 S2 0:SF4801 2.3 88.8 1.0 S3 0:SF4801 2.3 88.8 1.0 S4 0:SF4801 2.3 88.8 1.0 FE3 0:SF4801 2.7 88.8 1.0 FE2 0:SF4801 2.7 88.8 1.0 FE4 0:SF4801 2.7 88.8 1.0 CB 0:CYS115 3.5 99.0 1.0 CA 0:CYS115 3.8 99.0 1.0 S1 0:SF4801 3.9 88.8 1.0 CB 0:HIS117 4.2 99.9 1.0 N 0:LEU116 4.2 100.4 1.0 N 0:HIS117 4.4 99.9 1.0 C 0:CYS115 4.5 99.0 1.0 SG 0:CYS133 4.8 105.8 1.0 SG 0:CYS156 4.8 111.5 1.0 CB 0:CYS133 4.9 105.8 1.0 SG 0:CYS191 4.9 99.6 1.0 CA 0:HIS117 5.0 99.9 1.0

Iron binding site 2 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:88.8 occ:1.00 FE2 0:SF4801 0.0 88.8 1.0 SG 0:CYS156 2.3 111.5 1.0 S1 0:SF4801 2.3 88.8 1.0 S4 0:SF4801 2.3 88.8 1.0 S3 0:SF4801 2.3 88.8 1.0 FE4 0:SF4801 2.7 88.8 1.0 FE1 0:SF4801 2.7 88.8 1.0 FE3 0:SF4801 2.7 88.8 1.0 CB 0:CYS156 3.5 111.5 1.0 S2 0:SF4801 3.9 88.8 1.0 CB 0:HIS117 4.5 99.9 1.0 CD2 0:HIS117 4.6 99.9 1.0 CB 0:TYR158 4.7 100.7 1.0 SG 0:CYS191 4.7 99.6 1.0 SG 0:CYS115 4.8 99.0 1.0 SG 0:CYS133 4.8 105.8 1.0 CD1 0:TYR158 4.9 100.7 1.0 CG 0:HIS117 4.9 99.9 1.0 CA 0:CYS156 4.9 111.5 1.0 N 0:HIS159 5.0 105.2 1.0

Iron binding site 3 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:88.8 occ:1.00 FE3 0:SF4801 0.0 88.8 1.0 SG 0:CYS133 2.3 105.8 1.0 S1 0:SF4801 2.3 88.8 1.0 S4 0:SF4801 2.3 88.8 1.0 S2 0:SF4801 2.3 88.8 1.0 FE4 0:SF4801 2.7 88.8 1.0 FE1 0:SF4801 2.7 88.8 1.0 FE2 0:SF4801 2.7 88.8 1.0 CB 0:CYS133 3.0 105.8 1.0 CA 0:CYS133 3.8 105.8 1.0 S3 0:SF4801 3.9 88.8 1.0 NE 0:ARG111 4.4 94.5 1.0 CE2 0:PHE194 4.6 96.4 1.0 CG2 0:THR137 4.6 109.1 1.0 SG 0:CYS191 4.6 99.6 1.0 O 0:CYS133 4.6 105.8 1.0 C 0:CYS133 4.6 105.8 1.0 SG 0:CYS115 4.7 99.0 1.0 SG 0:CYS156 4.8 111.5 1.0 CD 0:ARG111 5.0 94.5 1.0 N 0:CYS133 5.0 105.8 1.0 CD2 0:PHE194 5.0 96.4 1.0

Iron binding site 4 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:88.8 occ:1.00 FE4 0:SF4801 0.0 88.8 1.0 SG 0:CYS191 2.3 99.6 1.0 S1 0:SF4801 2.3 88.8 1.0 S3 0:SF4801 2.3 88.8 1.0 S2 0:SF4801 2.3 88.8 1.0 FE3 0:SF4801 2.7 88.8 1.0 FE2 0:SF4801 2.7 88.8 1.0 FE1 0:SF4801 2.7 88.8 1.0 CB 0:CYS191 3.3 99.6 1.0 S4 0:SF4801 3.9 88.8 1.0 CA 0:CYS191 4.3 99.6 1.0 CD2 0:PHE194 4.5 96.4 1.0 SG 0:CYS133 4.6 105.8 1.0 SG 0:CYS156 4.7 111.5 1.0 SG 0:CYS115 4.8 99.0 1.0 CE2 0:PHE194 4.8 96.4 1.0 CB 0:TYR193 4.9 93.0 1.0

S.Schilbach, S.Aibara, C.Dienemann, F.Grabbe, P.Cramer. Structure of Rna Polymerase II Pre-Initiation Complex at 2.9 Angstrom Defines Initial Dna Opening Cell(Cambridge,Mass.) 2021.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2021.05.012