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Iron in PDB 7zih: Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128Enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128
All present enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128:
1.14.16.4; Protein crystallography data
The structure of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128, PDB code: 7zih
was solved by
A.Schuetz,
A.Gogolin,
J.Pfeifer,
K.Mallow,
M.Nazare,
E.Specker,
U.Heinemann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128
(pdb code 7zih). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128, PDB code: 7zih: Iron binding site 1 out of 1 in 7zihGo back to Iron Binding Sites List in 7zih
Iron binding site 1 out
of 1 in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Ag-01-128
Mono view Stereo pair view
Reference:
E.Specker,
S.Matthes,
R.Wesolowski,
A.Schutz,
M.Grohmann,
N.Alenina,
D.Pleimes,
K.Mallow,
M.Neuenschwander,
A.Gogolin,
M.Weise,
J.Pfeifer,
N.Ziebart,
U.Heinemann,
J.P.Von Kries,
M.Nazare,
M.Bader.
Structure-Based Design of Xanthine-Benzimidazole Derivatives As Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem. V. 65 11126 2022.
Page generated: Fri Aug 9 15:02:53 2024
ISSN: ISSN 0022-2623 PubMed: 35921615 DOI: 10.1021/ACS.JMEDCHEM.2C00598 |
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