Iron in PDB 8p7p: Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid]

Enzymatic activity of Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid]

All present enzymatic activity of Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid]:
1.21.3.1;

Protein crystallography data

The structure of Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid], PDB code: 8p7p was solved by P.Rabe, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.80 / 1.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 41.23, 74.49, 101.01, 90, 90, 90
R / Rfree (%) 20.7 / 24.2

Iron Binding Sites:

The binding sites of Iron atom in the Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid] (pdb code 8p7p). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid], PDB code: 8p7p:

Iron binding site 1 out of 1 in 8p7p

Go back to Iron Binding Sites List in 8p7p
Iron binding site 1 out of 1 in the Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid]


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino- 2-Methylpropane-1-Sulfonic Acid] within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe404

b:18.1
occ:1.00
 O A:HOH676 2.0 20.2 1.0
OD1 A:ASP216 2.1 16.7 1.0
NE2 A:HIS270 2.2 18.3 1.0
NE2 A:HIS214 2.2 16.8 1.0
O A:HOH511 2.3 18.4 1.0
S A:X2R401 2.4 19.6 1.0
CG A:ASP216 3.1 18.8 1.0
CE1 A:HIS270 3.1 18.0 1.0
CE1 A:HIS214 3.1 17.6 1.0
CD2 A:HIS270 3.2 19.7 1.0
CD2 A:HIS214 3.3 16.2 1.0
OD2 A:ASP216 3.4 17.7 1.0
C2 A:X2R401 3.4 18.4 1.0
O A:HOH740 3.9 25.2 1.0
O A:HOH728 4.1 24.2 1.0
O A:HOH748 4.2 24.8 1.0
ND1 A:HIS270 4.2 19.2 1.0
ND1 A:HIS214 4.2 17.5 1.0
CG A:HIS270 4.3 20.0 1.0
CG A:HIS214 4.4 15.3 1.0
CB A:ASP216 4.4 17.3 1.0
O1 A:X2R401 4.5 20.8 1.0
CA A:ASP216 4.7 16.3 1.0
O A:HOH678 4.7 18.3 1.0
C1 A:X2R401 4.8 20.1 1.0
N A:ASP216 5.0 19.8 1.0

Reference:

P.Rabe, C.J.Schofield. Isopenicillin N Synthase in Complex with Fe and Aad-Val-[(R)-1-Amino-2-Methylpropane-1-Sulfonic Acid] To Be Published.
Page generated: Sat Aug 10 08:50:34 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy