Iron in PDB 8qrn: Mt-Ssu in GTPBP8 Knock-Out Cells, State 4

The structure of Mt-Ssu in GTPBP8 Knock-Out Cells, State 4 also contains other interesting chemical elements:

Potassium	(K)	18 atoms
Zinc	(Zn)	1 atom
Magnesium	(Mg)	58 atoms

The binding sites of Iron atom in the Mt-Ssu in GTPBP8 Knock-Out Cells, State 4 (pdb code 8qrn). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Mt-Ssu in GTPBP8 Knock-Out Cells, State 4, PDB code: 8qrn:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Mt-Ssu in GTPBP8 Knock-Out Cells, State 4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Mt-Ssu in GTPBP8 Knock-Out Cells, State 4 within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe201 b:137.7 occ:1.00 FE1 P:FES201 0.0 137.7 1.0 S2 P:FES201 2.2 124.1 1.0 S1 P:FES201 2.2 129.9 1.0 SG P:CYS68 2.3 82.5 1.0 SG E:CYS105 2.3 111.5 1.0 CB E:CYS105 2.6 125.6 1.0 FE2 P:FES201 3.1 119.5 1.0 CB P:CYS68 3.5 78.9 1.0 CA E:CYS105 4.0 125.7 1.0 CA P:CYS68 4.2 78.5 1.0 C E:CYS105 4.4 125.1 1.0 N E:GLY107 4.4 121.6 1.0 SG P:CYS65 4.5 71.4 1.0 CA E:GLY107 4.6 120.2 1.0 O E:CYS105 4.8 122.1 1.0 SG P:CYS100 4.9 61.2 1.0 N E:GLU106 4.9 131.5 1.0 N E:CYS105 4.9 126.9 1.0

Iron binding site 2 out of 4 in the Mt-Ssu in GTPBP8 Knock-Out Cells, State 4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Mt-Ssu in GTPBP8 Knock-Out Cells, State 4 within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe201 b:119.5 occ:1.00 FE2 P:FES201 0.0 119.5 1.0 S2 P:FES201 2.2 124.1 1.0 S1 P:FES201 2.2 129.9 1.0 SG P:CYS65 2.3 71.4 1.0 SG P:CYS100 2.3 61.2 1.0 FE1 P:FES201 3.1 137.7 1.0 CB P:CYS100 3.3 64.8 1.0 CB P:CYS65 3.7 77.8 1.0 CB P:CYS68 4.3 78.9 1.0 CB P:LYS103 4.4 59.1 1.0 N P:CYS65 4.4 77.7 1.0 SG P:CYS68 4.4 82.5 1.0 N P:CYS100 4.4 66.3 1.0 CA P:CYS100 4.5 59.8 1.0 CA P:CYS68 4.5 78.5 1.0 SG E:CYS105 4.6 111.5 1.0 CA P:CYS65 4.7 79.5 1.0 N P:CYS68 4.8 79.9 1.0 CG P:LYS103 4.8 62.4 1.0 CD P:LYS103 4.9 54.1 1.0

Iron binding site 3 out of 4 in the Mt-Ssu in GTPBP8 Knock-Out Cells, State 4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Mt-Ssu in GTPBP8 Knock-Out Cells, State 4 within 5.0Å range: probe atom residue distance (Å) B Occ T:Fe201 b:117.5 occ:1.00 FE1 T:FES201 0.0 117.5 1.0 S2 T:FES201 2.2 109.1 1.0 S1 T:FES201 2.2 88.3 1.0 SG T:CYS149 2.3 77.6 1.0 SG M:CYS26 2.3 86.5 1.0 FE2 T:FES201 3.1 100.6 1.0 CB M:CYS26 3.4 69.2 1.0 CB T:CYS149 3.4 81.9 1.0 N M:CYS26 3.8 60.6 1.0 CA T:CYS149 4.1 78.1 1.0 CA M:CYS26 4.2 63.7 1.0 CD T:PRO150 4.3 79.6 1.0 SG T:CYS141 4.3 88.3 1.0 C M:GLY25 4.7 59.8 1.0 CA M:GLY25 4.8 57.1 1.0 N T:PRO150 4.9 81.7 1.0 C T:CYS149 5.0 82.0 1.0

Iron binding site 4 out of 4 in the Mt-Ssu in GTPBP8 Knock-Out Cells, State 4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Mt-Ssu in GTPBP8 Knock-Out Cells, State 4 within 5.0Å range: probe atom residue distance (Å) B Occ T:Fe201 b:100.6 occ:1.00 FE2 T:FES201 0.0 100.6 1.0 S2 T:FES201 2.2 109.1 1.0 S1 T:FES201 2.2 88.3 1.0 SG T:CYS141 2.3 88.3 1.0 SG T:CYS139 2.3 109.4 1.0 CB T:CYS139 2.7 106.4 1.0 FE1 T:FES201 3.1 117.5 1.0 CB T:CYS141 3.3 83.4 1.0 N T:CYS141 4.2 79.0 1.0 CA T:CYS139 4.2 104.9 1.0 CA T:CYS141 4.4 76.0 1.0 CB T:CYS149 4.5 81.9 1.0 CA M:GLY25 4.6 57.1 1.0 SG T:CYS149 4.6 77.6 1.0 C T:CYS139 4.7 103.2 1.0 N T:ILE140 4.7 91.9 1.0 CA T:CYS149 4.9 78.1 1.0 CG M:ARG29 5.0 51.5 1.0

M.Cipullo, G.Valentin Gese, S.Gopalakrishna, A.Krueger, V.Lobo, M.A.Pirozhkova, J.Marks, P.Palenkova, D.Shiriaev, Y.Liu, J.Misic, Y.Cai, M.Nguyen, A.Abdelbagi, X.Li, M.Minczuk, M.Hafner, D.Benhalevy, A.A.Sarshad, I.Attanasov, B.M.Hallberg, J.Rorbach. GTPBP8 Plays A Role in Mitoribosome Formation in Human Mitochondria Nat Commun 2024.
ISSN: ESSN 2041-1723