Iron in PDB 8qt6: Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase

The binding sites of Iron atom in the Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase (pdb code 8qt6). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase, PDB code: 8qt6:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe502 b:32.6 occ:1.00 FE A:HEM502 0.0 32.6 1.0 NB A:HEM502 2.0 21.8 1.0 NA A:HEM502 2.0 22.6 1.0 ND A:HEM502 2.1 21.9 1.0 NC A:HEM502 2.1 25.8 1.0 NE2 A:HIS83 2.3 10.6 1.0 NE2 A:HIS142 2.3 19.3 1.0 C1C A:HEM502 3.1 19.9 1.0 C1A A:HEM502 3.1 20.1 1.0 C4B A:HEM502 3.1 13.2 1.0 C4C A:HEM502 3.1 19.1 1.0 C1B A:HEM502 3.1 17.8 1.0 C4A A:HEM502 3.1 17.3 1.0 C1D A:HEM502 3.1 19.8 1.0 C4D A:HEM502 3.1 22.9 1.0 CD2 A:HIS83 3.1 7.2 1.0 CD2 A:HIS142 3.2 9.4 1.0 CE1 A:HIS142 3.3 19.2 1.0 CE1 A:HIS83 3.4 12.2 1.0 CHC A:HEM502 3.4 15.9 1.0 CHA A:HEM502 3.4 20.5 1.0 CHD A:HEM502 3.4 14.1 1.0 CHB A:HEM502 3.4 20.2 1.0 C2C A:HEM502 4.3 17.0 1.0 C3C A:HEM502 4.3 24.3 1.0 C2A A:HEM502 4.3 22.9 1.0 C3A A:HEM502 4.3 17.4 1.0 C2D A:HEM502 4.3 19.6 1.0 C3B A:HEM502 4.3 15.8 1.0 C2B A:HEM502 4.3 20.4 1.0 C3D A:HEM502 4.3 21.7 1.0 CG A:HIS83 4.3 19.2 1.0 ND1 A:HIS142 4.3 13.9 1.0 CG A:HIS142 4.4 21.2 1.0 ND1 A:HIS83 4.4 21.6 1.0

Iron binding site 2 out of 2 in the Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of Streptococcus Pneumoniae Nadph Oxidase within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe503 b:40.0 occ:1.00 FE A:HEM503 0.0 40.0 1.0 ND A:HEM503 2.0 21.3 1.0 NC A:HEM503 2.0 23.9 1.0 NB A:HEM503 2.1 23.2 1.0 NA A:HEM503 2.1 22.9 1.0 NE2 A:HIS69 2.1 25.1 1.0 NE2 A:HIS129 2.2 14.9 1.0 CE1 A:HIS69 2.7 18.4 1.0 C4C A:HEM503 3.0 20.0 1.0 C4A A:HEM503 3.1 18.4 1.0 C1D A:HEM503 3.1 19.6 1.0 C1C A:HEM503 3.1 17.6 1.0 C1A A:HEM503 3.1 20.9 1.0 C1B A:HEM503 3.1 17.2 1.0 C4D A:HEM503 3.1 18.2 1.0 C4B A:HEM503 3.1 10.5 1.0 CE1 A:HIS129 3.1 16.7 1.0 CD2 A:HIS129 3.1 11.7 1.0 CD2 A:HIS69 3.3 26.1 1.0 CHD A:HEM503 3.4 19.5 1.0 CHB A:HEM503 3.4 15.9 1.0 CHC A:HEM503 3.4 13.3 1.0 CHA A:HEM503 3.4 17.3 1.0 ND1 A:HIS69 3.9 17.7 1.0 ND1 A:HIS129 4.2 21.0 1.0 C3C A:HEM503 4.2 21.7 1.0 C2C A:HEM503 4.3 23.5 1.0 C3A A:HEM503 4.3 20.9 1.0 C2A A:HEM503 4.3 23.1 1.0 CG A:HIS69 4.3 27.5 1.0 CG A:HIS129 4.3 24.1 1.0 C2D A:HEM503 4.3 28.8 1.0 C3D A:HEM503 4.3 24.0 1.0 C2B A:HEM503 4.3 23.4 1.0 C3B A:HEM503 4.3 20.8 1.0 CH2 A:TRP125 5.0 19.9 1.0

V.R.A.Dubach, P.San Segundo-Acosta, B.J.Murphy. Structural and Mechanistic Insight Into Streptococcus Pneumoniae Nadph Oxidase To Be Published 2024.
DOI: 10.1038/S41594-024-01348-W