Iron in PDB 8qu9: Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex

The binding sites of Iron atom in the Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex (pdb code 8qu9). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex, PDB code: 8qu9:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe201 b:87.1 occ:1.00 OE2 A:GLU63 2.5 41.2 1.0 OE2 A:GLU108 2.5 42.0 1.0 NE2 A:GLN142 3.6 38.4 1.0 CD A:GLU63 3.6 39.3 1.0 CD A:GLU108 3.6 39.5 1.0 OE1 A:GLU141 3.9 47.0 1.0 OE1 A:GLU63 4.0 38.0 1.0 CB A:ALA145 4.1 23.9 1.0 CE1 A:HIS66 4.3 33.3 1.0 OE1 A:GLU108 4.4 44.6 1.0 FE A:FE202 4.5 65.7 1.0 OE1 A:GLU62 4.5 44.4 1.0 CG A:GLU108 4.5 25.7 1.0 ND1 A:HIS66 4.7 32.1 1.0 CD A:GLN142 4.8 37.5 1.0 CD A:GLU141 4.9 45.1 1.0 CG A:GLU63 4.9 37.8 1.0 NE2 A:GLN59 4.9 35.4 1.0 OE2 A:GLU141 4.9 39.6 1.0

Iron binding site 2 out of 2 in the Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H- Ferritin) Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe202 b:65.7 occ:1.00 ND1 A:HIS66 2.2 32.1 1.0 OE1 A:GLU28 2.8 42.7 1.0 CG A:HIS66 2.9 34.6 1.0 CE1 A:HIS66 2.9 33.3 1.0 OE1 A:GLU63 3.1 38.0 1.0 CB A:HIS66 3.4 31.1 1.0 OE2 A:GLU141 3.4 39.6 1.0 CD2 A:HIS66 3.8 39.1 1.0 NE2 A:HIS66 3.8 41.8 1.0 CD A:GLU28 3.9 39.2 1.0 CD A:GLU63 4.1 39.3 1.0 CD A:GLU141 4.2 45.1 1.0 NE2 A:GLN142 4.2 38.4 1.0 OE2 A:GLU28 4.3 36.5 1.0 OE2 A:GLU63 4.3 41.2 1.0 CD1 A:TYR138 4.4 42.5 1.0 OE1 A:GLU141 4.4 47.0 1.0 FE A:FE201 4.5 87.1 1.0 CE1 A:TYR138 4.5 39.9 1.0 CG1 A:VAL111 4.7 29.1 1.0 CA A:HIS66 4.9 30.7 1.0

F.Hoelzgen, T.T.P.Nguyen, E.Klukin, M.Boumaiza, A.K.Srivastava, E.Y.Kim, R.Zalk, A.Shahar, S.Cohen-Schwartz, E.G.Meyron-Holtz, F.Bou-Abdallah, J.D.Mancias, G.A.Frank. Structural Basis For the Intracellular Regulation of Ferritin Degradation. Nat Commun V. 15 3802 2024.
ISSN: ESSN 2041-1723
PubMed: 38714719
DOI: 10.1038/S41467-024-48151-1