Iron in PDB 8sf2: Crystal Structure of the Engineered Ssopox Variant IG7

All present enzymatic activity of Crystal Structure of the Engineered Ssopox Variant IG7:
3.1.8.1;

The structure of Crystal Structure of the Engineered Ssopox Variant IG7, PDB code: 8sf2 was solved by P.Jacquet, R.Billot, A.Shimon, N.Hoekstra, C.Bergonzi, A.Jenks, D.Daude, M.H.Elias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.26 / 1.50
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	65.43, 74.66, 137.47, 90, 90, 90
R / Rfree (%)	15.7 / 19

The structure of Crystal Structure of the Engineered Ssopox Variant IG7 also contains other interesting chemical elements:

Cobalt

(Co)

1 atom

The binding sites of Iron atom in the Crystal Structure of the Engineered Ssopox Variant IG7 (pdb code 8sf2). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of the Engineered Ssopox Variant IG7, PDB code: 8sf2:

Iron binding site 1 out of 1 in the Crystal Structure of the Engineered Ssopox Variant IG7


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of the Engineered Ssopox Variant IG7 within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe401 b:16.8 occ:1.00 O2 D:PO4403 2.0 16.8 0.7 NE2 D:HIS24 2.1 17.3 1.0 NE2 D:HIS22 2.1 17.4 1.0 OQ1 D:KCX137 2.1 17.6 1.0 OD1 D:ASP256 2.2 18.6 1.0 O3 D:PO4403 2.4 31.3 0.7 P D:PO4403 2.6 39.6 0.7 CE1 D:HIS24 3.0 15.2 1.0 CX D:KCX137 3.0 16.9 1.0 CD2 D:HIS22 3.0 16.0 1.0 CE1 D:HIS22 3.1 16.4 1.0 CD2 D:HIS24 3.1 15.3 1.0 CG D:ASP256 3.1 19.1 1.0 OQ2 D:KCX137 3.3 16.4 1.0 OD2 D:ASP256 3.4 20.3 1.0 CO D:CO402 3.5 19.9 1.0 O1 D:PO4403 3.7 33.0 0.7 O4 D:PO4403 3.8 18.5 0.7 NZ D:KCX137 4.1 16.5 1.0 ND1 D:HIS24 4.1 16.2 1.0 ND1 D:HIS22 4.2 15.2 1.0 CG D:HIS22 4.2 14.4 1.0 CG D:HIS24 4.2 15.6 1.0 CB D:ASP256 4.4 19.6 1.0 CE1 D:HIS199 4.4 19.0 1.0 CG D:PRO67 4.5 17.0 1.0 NE2 D:HIS199 4.6 19.4 1.0 O D:HOH663 4.6 49.3 1.0 CA D:ASP256 4.9 20.1 1.0

P.Jacquet, R.Billot, A.Shimon, N.Hoekstra, C.Bergonzi, A.Jenks, E.Chabriere, D.Daude, M.H.Elias. Changes in Active Site Loops Conformation Relates to A Transition From Lactonase to Phosphotriesterase To Be Published.