Iron in PDB 8so0: Cryo-Em Structure of the PP2A:B55-FAM122A Complex

All present enzymatic activity of Cryo-Em Structure of the PP2A:B55-FAM122A Complex:
3.1.3.16;

The structure of Cryo-Em Structure of the PP2A:B55-FAM122A Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Iron atom in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex (pdb code 8so0). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex, PDB code: 8so0:

Iron binding site 1 out of 1 in the Cryo-Em Structure of the PP2A:B55-FAM122A Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of the PP2A:B55-FAM122A Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe401 b:113.8 occ:1.00 OD2 C:ASP85 1.9 81.7 1.0 ND1 C:HIS241 2.0 76.6 1.0 NE2 C:HIS167 2.1 62.3 1.0 OD1 C:ASN117 2.1 87.1 1.0 CG C:ASP85 2.7 73.0 1.0 HE1 C:HIS167 2.8 65.8 1.0 CE1 C:HIS167 2.8 64.8 1.0 CE1 C:HIS241 2.8 80.0 1.0 ZN C:ZN402 2.9 135.8 1.0 HE1 C:HIS241 2.9 74.8 1.0 OD1 C:ASP85 3.0 83.3 1.0 HA C:HIS241 3.1 72.4 1.0 CG C:HIS241 3.1 68.0 1.0 CG C:ASN117 3.2 76.6 1.0 HD2 C:HIS118 3.2 76.5 1.0 CD2 C:HIS167 3.3 61.8 1.0 HB2 C:HIS241 3.4 73.5 1.0 HD22 C:ASN117 3.5 79.6 1.0 CB C:HIS241 3.6 73.3 1.0 HD2 C:HIS167 3.6 65.7 1.0 OD2 C:ASP57 3.6 78.0 1.0 H C:ASN117 3.7 80.4 1.0 ND2 C:ASN117 3.7 79.4 1.0 CA C:HIS241 3.8 69.0 1.0 ND1 C:HIS167 4.0 67.6 1.0 NE2 C:HIS241 4.0 81.5 1.0 CB C:ASP85 4.0 65.3 1.0 CD2 C:HIS118 4.1 78.3 1.0 HB2 C:ASP85 4.1 72.8 1.0 CD2 C:HIS241 4.1 67.1 1.0 H C:HIS118 4.2 75.9 1.0 CG C:HIS167 4.3 60.4 1.0 CB C:ASN117 4.4 77.5 1.0 N C:ASN117 4.4 82.6 1.0 HB3 C:ASN117 4.4 79.7 1.0 O C:HIS241 4.4 79.1 1.0 HB3 C:ASP85 4.4 71.8 1.0 CG C:ASP57 4.4 71.8 1.0 HB3 C:HIS241 4.5 73.4 1.0 HD21 C:ASN117 4.6 80.2 1.0 HE1 C:HIS59 4.6 64.5 1.0 C C:HIS241 4.6 73.6 1.0 OD1 C:ASP57 4.7 74.1 1.0 HD1 C:HIS167 4.7 66.0 1.0 HE2 C:HIS241 4.7 76.1 1.0 NE2 C:HIS59 4.7 67.8 1.0 HA3 C:GLY116 4.8 74.7 1.0 N C:HIS241 4.8 63.4 1.0 NE2 C:HIS118 4.8 78.7 1.0 H C:HIS241 4.9 71.9 1.0 N C:HIS118 4.9 66.5 1.0 CA C:ASN117 4.9 77.5 1.0 CE1 C:HIS59 5.0 69.8 1.0

S.K.R.Padi, M.R.Vos, A.D.S.Santiago, R.J.Godek, J.R.Fuller, M.S.Kelker, R.Page, W.Peti. Cryo-Em Structure of PP2A:B55-FAM122A Reveals A Bipartite Mechanism of FAM122A-Mediated Inhibition and A Motif That Confers Binding Specificity to PP2A:B55 To Be Published.