Iron in PDB 8vy3: Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)

All present enzymatic activity of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio):
2.7.7.102; 2.7.7.7;

The structure of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) also contains other interesting chemical elements:

Zinc

(Zn)

3 atoms

The binding sites of Iron atom in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) (pdb code 8vy3). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio), PDB code: 8vy3:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe601 b:38.0 occ:1.00 FE1 B:SF4601 0.0 38.0 1.0 SG B:CYS367 2.3 29.8 1.0 S3 B:SF4601 2.3 15.4 1.0 S4 B:SF4601 2.3 32.4 1.0 S2 B:SF4601 2.3 34.2 1.0 FE2 B:SF4601 2.7 39.1 1.0 FE3 B:SF4601 2.7 30.6 1.0 FE4 B:SF4601 2.7 36.7 1.0 CB B:CYS367 3.8 14.3 1.0 S1 B:SF4601 3.9 28.6 1.0 CA B:CYS367 4.3 4.1 1.0 SG B:CYS424 4.7 30.1 1.0 SG B:CYS384 4.7 24.4 1.0 CD2 B:LEU441 4.8 25.6 1.0 CG B:PRO444 4.8 20.5 1.0 SG B:CYS287 4.8 30.9 1.0

Iron binding site 2 out of 4 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe601 b:39.1 occ:1.00 FE2 B:SF4601 0.0 39.1 1.0 SG B:CYS384 2.3 24.4 1.0 S4 B:SF4601 2.3 32.4 1.0 S1 B:SF4601 2.3 28.6 1.0 S3 B:SF4601 2.3 15.4 1.0 FE1 B:SF4601 2.7 38.0 1.0 FE4 B:SF4601 2.7 36.7 1.0 FE3 B:SF4601 2.7 30.6 1.0 CB B:CYS384 3.4 16.8 1.0 S2 B:SF4601 3.9 34.2 1.0 CA B:CYS384 4.1 8.6 1.0 CD2 B:PHE386 4.1 19.0 1.0 CD B:PRO385 4.3 19.2 1.0 SG B:CYS367 4.4 29.8 1.0 SG B:CYS287 4.6 30.9 1.0 N B:PRO385 4.7 21.7 1.0 C B:CYS384 4.7 25.6 1.0 CE2 B:PHE386 4.8 20.7 1.0 SG B:CYS424 4.8 30.1 1.0

Iron binding site 3 out of 4 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe601 b:30.6 occ:1.00 FE3 B:SF4601 0.0 30.6 1.0 SG B:CYS424 2.3 30.1 1.0 S1 B:SF4601 2.3 28.6 1.0 S4 B:SF4601 2.3 32.4 1.0 S2 B:SF4601 2.3 34.2 1.0 FE1 B:SF4601 2.7 38.0 1.0 FE4 B:SF4601 2.7 36.7 1.0 FE2 B:SF4601 2.7 39.1 1.0 CB B:CYS424 3.2 24.1 1.0 S3 B:SF4601 3.9 15.4 1.0 CE2 B:PHE386 4.2 20.7 1.0 CD B:PRO286 4.3 23.9 1.0 CD2 B:PHE386 4.3 19.0 1.0 CD2 B:LEU441 4.4 25.6 1.0 CA B:CYS424 4.6 23.4 1.0 CB B:PRO285 4.6 27.6 1.0 SG B:CYS367 4.7 29.8 1.0 SG B:CYS287 4.8 30.9 1.0 SG B:CYS384 4.9 24.4 1.0 CG B:PRO286 4.9 23.8 1.0

Iron binding site 4 out of 4 in the Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Dna Polymerase Alpha/Primase - AAVLEA1 (1:40 Molar Ratio) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe601 b:36.7 occ:1.00 FE4 B:SF4601 0.0 36.7 1.0 SG B:CYS287 2.3 30.9 1.0 S3 B:SF4601 2.3 15.4 1.0 S1 B:SF4601 2.3 28.6 1.0 S2 B:SF4601 2.3 34.2 1.0 FE1 B:SF4601 2.7 38.0 1.0 FE2 B:SF4601 2.7 39.1 1.0 FE3 B:SF4601 2.7 30.6 1.0 CB B:CYS287 3.6 22.2 1.0 S4 B:SF4601 3.9 32.4 1.0 CB B:PRO285 4.2 27.6 1.0 N B:CYS287 4.2 19.9 1.0 CA B:CYS287 4.5 20.6 1.0 CG B:PRO285 4.6 25.1 1.0 CG B:PRO444 4.6 20.5 1.0 SG B:CYS384 4.7 24.4 1.0 SG B:CYS424 4.8 30.1 1.0 CD B:PRO286 4.9 23.9 1.0 SG B:CYS367 4.9 29.8 1.0 CD B:PRO385 4.9 19.2 1.0 N B:PRO286 5.0 15.6 1.0

K.M.Abe, G.Li, T.Grant, C.J.Lim. Human PRC2 - AAVLEA1 (1:40 Molar Ratio) To Be Published.