Iron in PDB 8wb3: Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading

All present enzymatic activity of Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading:
1.16.3.1;

The structure of Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading, PDB code: 8wb3 was solved by T.Zhang, R.Jiao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.85 / 2.49
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	181.919, 181.919, 181.919, 90, 90, 90
R / Rfree (%)	18.4 / 23.5

The structure of Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading also contains other interesting chemical elements:

Calcium

(Ca)

3 atoms

The binding sites of Iron atom in the Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading (pdb code 8wb3). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading, PDB code: 8wb3:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe201 b:58.5 occ:1.00 OE1 A:GLU62 2.1 49.6 1.0 O A:HOH313 2.2 52.3 1.0 O A:HOH302 2.5 47.4 1.0 OE1 A:GLU27 2.5 43.0 1.0 ND1 A:HIS65 2.5 40.9 1.0 CD A:GLU62 3.1 49.1 1.0 OE2 A:GLU62 3.4 53.1 1.0 CD A:GLU27 3.4 44.5 1.0 CE1 A:HIS65 3.4 47.9 1.0 CG A:HIS65 3.4 38.9 1.0 O A:HOH336 3.7 43.2 1.0 CB A:HIS65 3.7 38.5 1.0 OE2 A:GLU27 3.7 45.9 1.0 OE1 A:GLN141 3.9 45.1 1.0 CG A:GLU62 4.4 39.5 1.0 CG1 A:VAL110 4.5 35.4 1.0 NE2 A:HIS65 4.5 51.0 1.0 CD2 A:HIS65 4.6 45.0 1.0 CA A:GLU62 4.6 36.1 1.0 CB A:GLU62 4.7 34.6 1.0 CG A:GLU27 4.7 34.9 1.0 CD A:GLN141 4.8 39.6 1.0 CB A:GLU27 5.0 29.0 1.0

Iron binding site 2 out of 2 in the Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human H Chain Ferritin Mutant-K86Q with 2 Fe(III)/Subunit Loading within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe202 b:84.8 occ:1.00 OE2 A:GLU107 2.8 51.3 1.0 OE2 A:GLU62 2.8 53.1 1.0 O A:HOH336 3.0 43.2 1.0 CG A:GLN58 3.4 41.8 1.0 NE2 A:GLN58 3.5 48.9 1.0 CD A:GLU107 3.8 47.8 1.0 CD A:GLN58 4.0 45.6 1.0 CD A:GLU62 4.0 49.1 1.0 CB A:ALA144 4.3 29.8 1.0 OE1 A:GLU107 4.3 50.6 1.0 OH A:TYR34 4.4 46.3 1.0 O A:HOH313 4.4 52.3 1.0 CE2 A:TYR34 4.5 31.1 1.0 CB A:GLN58 4.6 35.7 1.0 CG A:GLU62 4.7 39.5 1.0 CZ A:TYR34 4.8 39.6 1.0 OE1 A:GLU62 5.0 49.6 1.0 CG A:GLU107 5.0 43.4 1.0

T.Zhang, R.Jiao. Human H Chain Ferritin with Mutant-K86Q 2 Fe(III)/Subunit Loading To Be Published.