Iron in PDB 8xf8: High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B

The structure of High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B, PDB code: 8xf8 was solved by J.M.M.Caaveiro, J.Fernandez-Perez, K.Tsumoto, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.50 / 1.15
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	76.223, 76.223, 102.502, 90, 90, 120
R / Rfree (%)	13.5 / 15.3

The structure of High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B also contains other interesting chemical elements:

Sodium	(Na)	2 atoms
Zinc	(Zn)	5 atoms

The binding sites of Iron atom in the High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B (pdb code 8xf8). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B, PDB code: 8xf8:

Iron binding site 1 out of 1 in the High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of High-Resolution Structure of the Siderophore Periplasmic Binding Protein Ftsb From Streptococcus Pyogenes with Ferrioxamine B within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:13.7 occ:1.00 FE A:0UE401 0.0 13.7 1.0 O32 A:0UE401 2.0 15.9 1.0 O31 A:0UE401 2.0 14.9 1.0 O11 A:0UE401 2.0 15.1 1.0 O21 A:0UE401 2.0 15.5 1.0 O22 A:0UE401 2.0 12.8 1.0 O12 A:0UE401 2.0 11.9 1.0 C31 A:0UE401 2.7 14.7 1.0 N31 A:0UE401 2.7 15.8 1.0 N11 A:0UE401 2.8 14.7 1.0 N21 A:0UE401 2.8 13.7 1.0 C11 A:0UE401 2.8 12.8 1.0 C21 A:0UE401 2.9 12.5 1.0 NE1 A:TRP204 4.0 11.3 1.0 N44 A:0UE401 4.1 25.7 1.0 C29 A:0UE401 4.1 16.4 1.0 O A:HOH702 4.1 22.4 1.0 C32 A:0UE401 4.1 16.5 1.0 C39 A:0UE401 4.2 16.9 1.0 NH2 A:ARG206 4.2 10.9 1.0 C19 A:0UE401 4.2 14.2 1.0 NH1 A:ARG206 4.3 10.0 1.0 C22 A:0UE401 4.3 12.5 1.0 C12 A:0UE401 4.3 11.8 1.0 C42 A:0UE401 4.3 22.8 1.0 C43 A:0UE401 4.3 24.6 1.0 C27 A:0UE401 4.5 15.9 1.0 C28 A:0UE401 4.6 16.0 1.0 C40 A:0UE401 4.7 19.4 1.0 CD1 A:TRP204 4.7 10.6 1.0 CZ A:ARG206 4.7 9.9 1.0 C18 A:0UE401 4.8 15.0 1.0 C13 A:0UE401 4.9 12.3 1.0 C24 A:0UE401 4.9 12.8 1.0 C23 A:0UE401 4.9 12.8 1.0 CE2 A:TRP204 4.9 11.6 1.0

J.Fernandez-Perez, J.M.M.Caaveiro, A.Senoo, M.Nakakido, S.De Vega, I.Nakagawa, K.Tsumoto. Conserved Binding Mechanism For Ligand Promiscuity in the Hydroxamate Siderophore Binding Protein Ftsb From Streptococcus Pyogenes Structure.
ISSN: ISSN 0969-2126
DOI: 10.1016/J.STR.2024.09.018