Iron in PDB 9c0q: Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger

All present enzymatic activity of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger:
1.2.7.4;

The structure of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger also contains other interesting chemical elements:

Nickel

(Ni)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 36;

Binding sites:

The binding sites of Iron atom in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger (pdb code 9c0q). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 36 binding sites of Iron where determined in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger, PDB code: 9c0q:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe900 b:32.5 occ:1.00 FE1 A:SF4900 0.0 32.5 1.0 S4 A:SF4900 2.3 31.2 1.0 S3 A:SF4900 2.3 38.0 1.0 S2 A:SF4900 2.3 28.5 1.0 SG A:CYS83 2.3 41.3 1.0 FE3 A:SF4900 2.7 42.8 1.0 FE2 A:SF4900 2.7 47.6 1.0 FE4 A:SF4900 2.7 42.1 1.0 CB A:CYS83 3.4 29.8 1.0 N A:ALA92 3.8 30.5 1.0 S1 A:SF4900 3.9 32.8 1.0 CA A:GLY81 4.3 28.3 1.0 CB A:ALA92 4.4 25.1 1.0 N A:CYS83 4.4 26.3 1.0 CA A:GLY91 4.5 25.2 1.0 N A:GLY81 4.5 29.1 1.0 CA A:CYS83 4.5 28.9 1.0 O A:CYS75 4.6 28.0 1.0 CA A:ALA92 4.6 25.8 1.0 C A:GLY91 4.6 30.4 1.0 N A:CYS93 4.7 25.3 1.0 SG A:CYS75 4.7 27.1 1.0 SG A:CYS78 4.7 21.5 1.0 SG A:CYS93 4.8 29.2 1.0 CB A:CYS75 4.8 25.0 1.0 CB A:PHE80 4.8 29.0 1.0 C A:PHE80 4.9 28.2 1.0

Iron binding site 2 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe900 b:47.6 occ:1.00 FE2 A:SF4900 0.0 47.6 1.0 S4 A:SF4900 2.3 31.2 1.0 S3 A:SF4900 2.3 38.0 1.0 SG A:CYS93 2.3 29.2 1.0 S1 A:SF4900 2.3 32.8 1.0 FE3 A:SF4900 2.7 42.8 1.0 FE4 A:SF4900 2.7 42.1 1.0 FE1 A:SF4900 2.7 32.5 1.0 CB A:CYS93 3.3 19.8 1.0 N A:CYS93 3.8 25.3 1.0 S2 A:SF4900 3.9 28.5 1.0 CA A:CYS93 4.1 21.2 1.0 N A:ALA92 4.5 30.5 1.0 NH2 A:ARG103 4.7 20.4 1.0 SG A:CYS78 4.7 21.5 1.0 SG A:CYS75 4.7 27.1 1.0 SG A:CYS83 4.8 41.3 1.0 C A:ALA92 4.8 25.8 1.0 CB A:LEU95 4.9 21.9 1.0 C A:CYS93 5.0 23.3 1.0

Iron binding site 3 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe900 b:42.8 occ:1.00 FE3 A:SF4900 0.0 42.8 1.0 SG A:CYS75 2.3 27.1 1.0 S4 A:SF4900 2.3 31.2 1.0 S1 A:SF4900 2.3 32.8 1.0 S2 A:SF4900 2.3 28.5 1.0 FE2 A:SF4900 2.7 47.6 1.0 FE1 A:SF4900 2.7 32.5 1.0 FE4 A:SF4900 2.7 42.1 1.0 CB A:CYS75 3.2 25.0 1.0 NH2 A:ARG103 3.9 20.4 1.0 S3 A:SF4900 3.9 38.0 1.0 O A:CYS75 4.0 28.0 1.0 CB A:TYR77 4.1 21.7 1.0 C A:CYS75 4.2 27.6 1.0 N A:TYR77 4.3 25.9 1.0 CA A:CYS75 4.3 26.3 1.0 N A:CYS78 4.6 28.3 1.0 SG A:CYS83 4.7 41.3 1.0 CA A:TYR77 4.7 24.7 1.0 N A:CYS76 4.8 33.0 1.0 SG A:CYS93 4.8 29.2 1.0 SG A:CYS78 4.9 21.5 1.0

Iron binding site 4 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe900 b:42.1 occ:1.00 FE4 A:SF4900 0.0 42.1 1.0 S2 A:SF4900 2.3 28.5 1.0 S3 A:SF4900 2.3 38.0 1.0 S1 A:SF4900 2.3 32.8 1.0 SG A:CYS78 2.3 21.5 1.0 FE2 A:SF4900 2.7 47.6 1.0 FE3 A:SF4900 2.7 42.8 1.0 FE1 A:SF4900 2.7 32.5 1.0 CB A:CYS78 3.5 22.4 1.0 N A:CYS78 3.7 28.3 1.0 S4 A:SF4900 3.9 31.2 1.0 CA A:CYS78 4.1 24.9 1.0 CB A:PHE80 4.2 29.0 1.0 C A:CYS78 4.4 27.0 1.0 O A:CYS78 4.4 32.1 1.0 N A:GLY81 4.5 29.1 1.0 SG A:CYS93 4.7 29.2 1.0 SG A:CYS83 4.8 41.3 1.0 N A:PHE80 4.8 22.6 1.0 SG A:CYS75 4.9 27.1 1.0 C A:TYR77 4.9 30.9 1.0 CA A:PHE80 4.9 25.3 1.0 CB A:TYR77 4.9 21.7 1.0 CB A:ALA183 4.9 21.2 1.0 C A:PHE80 5.0 28.2 1.0

Iron binding site 5 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe901 b:73.3 occ:1.00 FE1 A:RQM901 0.0 73.3 1.0 S2 A:RQM901 2.3 83.1 1.0 S3 A:RQM901 2.3 56.5 1.0 S4 A:RQM901 2.3 54.5 1.0 SG A:CYS322 2.4 49.5 1.0 FE3 A:RQM901 2.6 98.5 1.0 FE4 A:RQM901 2.8 75.0 1.0 NI A:RQM901 3.4 74.2 0.5 FE2 A:RQM901 3.5 64.9 1.0 CB A:CYS322 3.6 50.1 1.0 CE1 A:HIS249 3.6 43.7 1.0 S1 A:RQM901 3.8 69.1 1.0 OH A:TYR631 3.8 51.5 1.0 NE2 A:HIS249 4.1 46.6 1.0 NZ A:LYS634 4.3 33.0 1.0 CZ A:TYR631 4.5 41.1 1.0 SG A:CYS520 4.6 36.9 1.0 CE2 A:TYR631 4.6 38.0 1.0 SG A:CYS276 4.7 64.3 1.0 ND1 A:HIS249 4.8 39.7 1.0 OG A:SER632 4.8 29.8 1.0 CA A:CYS322 4.9 42.0 1.0

Iron binding site 6 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe901 b:64.9 occ:1.00 FE2 A:RQM901 0.0 64.9 1.0 NE2 A:HIS249 2.0 46.6 1.0 SG A:CYS277 2.3 52.7 1.0 S3 A:RQM901 2.3 56.5 1.0 NI A:RQM901 2.4 74.2 0.5 CE1 A:HIS249 2.7 43.7 1.0 CD2 A:HIS249 3.1 43.9 1.0 CB A:CYS277 3.2 41.9 1.0 FE1 A:RQM901 3.5 73.3 1.0 S1 A:RQM901 3.6 69.1 1.0 FE4 A:RQM901 3.6 75.0 1.0 S4 A:RQM901 3.8 54.5 1.0 SG A:CYS584 3.8 66.5 1.0 ND1 A:HIS249 3.8 39.7 1.0 N A:CYS277 4.0 41.1 1.0 CB A:CYS584 4.0 43.9 1.0 CG A:HIS249 4.0 37.8 1.0 NZ A:LYS634 4.1 33.0 1.0 CA A:CYS277 4.2 45.3 1.0 FE3 A:RQM901 4.4 98.5 1.0 N A:CYS584 4.5 36.8 1.0 CA A:CYS584 4.9 37.7 1.0 CB A:CYS276 5.0 47.1 1.0

Iron binding site 7 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe901 b:98.5 occ:1.00 FE3 A:RQM901 0.0 98.5 1.0 S4 A:RQM901 2.3 54.5 1.0 S2 A:RQM901 2.3 83.1 1.0 S1 A:RQM901 2.3 69.1 1.0 SG A:CYS520 2.4 36.9 1.0 FE1 A:RQM901 2.6 73.3 1.0 NI A:RQM901 2.7 74.2 0.5 FE4 A:RQM901 2.8 75.0 1.0 CB A:CYS520 3.1 40.4 1.0 CA A:CYS520 3.5 37.6 1.0 OG A:SER632 3.7 29.8 1.0 S3 A:RQM901 3.9 56.5 1.0 N A:CYS520 4.0 31.6 1.0 FE2 A:RQM901 4.4 64.9 1.0 C A:GLY519 4.4 29.2 1.0 CE2 A:TYR631 4.4 38.0 1.0 O A:GLY519 4.4 33.9 1.0 SG A:CYS584 4.6 66.5 1.0 SG A:CYS322 4.6 49.5 1.0 C A:CYS520 4.8 38.6 1.0 CB A:SER632 4.8 25.2 1.0 OH A:TYR631 4.8 51.5 1.0 CZ A:TYR631 4.9 41.1 1.0 SG A:CYS549 4.9 64.6 1.0

Iron binding site 8 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe901 b:75.0 occ:1.00 FE4 A:RQM901 0.0 75.0 1.0 S2 A:RQM901 2.3 83.1 1.0 S1 A:RQM901 2.3 69.1 1.0 S3 A:RQM901 2.3 56.5 1.0 SG A:CYS549 2.4 64.6 1.0 FE3 A:RQM901 2.8 98.5 1.0 FE1 A:RQM901 2.8 73.3 1.0 CB A:CYS549 3.5 44.3 1.0 NI A:RQM901 3.5 74.2 0.5 FE2 A:RQM901 3.6 64.9 1.0 S4 A:RQM901 4.1 54.5 1.0 N A:CYS549 4.2 37.1 1.0 CA A:CYS520 4.4 37.6 1.0 CA A:CYS549 4.4 39.2 1.0 SG A:CYS277 4.6 52.7 1.0 O A:GLY519 4.7 33.9 1.0 CB A:CYS520 4.7 40.4 1.0 SG A:CYS520 4.9 36.9 1.0 SG A:CYS276 4.9 64.3 1.0 SG A:CYS322 5.0 49.5 1.0 CG2 A:ILE301 5.0 52.8 1.0

Iron binding site 9 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe902 b:120.6 occ:1.00 FE1 A:SF4902 0.0 120.6 1.0 S3 A:SF4902 2.3 88.1 1.0 S2 A:SF4902 2.3 121.2 1.0 SG B:CYS72 2.3 59.4 1.0 S4 A:SF4902 2.3 92.6 1.0 FE2 A:SF4902 2.7 133.3 1.0 FE4 A:SF4902 2.7 140.6 1.0 FE3 A:SF4902 2.7 106.3 1.0 CB B:CYS72 3.4 35.9 1.0 S1 A:SF4902 3.9 99.4 1.0 SG A:CYS76 4.3 59.5 1.0 CA B:CYS72 4.8 33.4 1.0 SG A:CYS72 4.8 79.9 1.0 SG B:CYS76 4.9 38.0 1.0 O B:GLN74 4.9 29.8 1.0

Iron binding site 10 out of 36 in the Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Carbon Monoxide Dehydrogenase (Codh) From Methanosarcina Thermophila, Specimen Prepared on Blot Plunger within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe902 b:133.3 occ:1.00 FE2 A:SF4902 0.0 133.3 1.0 SG A:CYS72 2.3 79.9 1.0 S3 A:SF4902 2.3 88.1 1.0 S1 A:SF4902 2.3 99.4 1.0 S4 A:SF4902 2.3 92.6 1.0 FE1 A:SF4902 2.7 120.6 1.0 FE4 A:SF4902 2.7 140.6 1.0 FE3 A:SF4902 2.7 106.3 1.0 CB A:CYS72 3.1 46.4 1.0 S2 A:SF4902 3.9 121.2 1.0 O A:GLN74 4.1 36.6 1.0 CB A:GLN74 4.5 32.4 1.0 CA A:CYS72 4.5 39.3 1.0 C A:GLN74 4.7 31.7 1.0 SG B:CYS72 4.7 59.4 1.0 SG B:CYS76 4.8 38.0 1.0 N A:GLN74 4.8 33.7 1.0 CA A:GLN74 4.9 29.8 1.0 SG A:CYS76 5.0 59.5 1.0

A.Biester, D.A.Grahame, C.L.Drennan. Capturing A Methanogenic Carbon Monoxide Dehydrogenase/Acetyl-Coa Synthase Complex Via Cryogenic Electron Microscopy. Proc.Natl.Acad.Sci.Usa V. 121 95121 2024.
ISSN: ESSN 1091-6490
PubMed: 39361653
DOI: 10.1073/PNAS.2410995121