Iron in PDB 9c8v: Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
Enzymatic activity of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
All present enzymatic activity of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm):
2.7.7.102;
2.7.7.7;
Other elements in 9c8v:
The structure of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
(pdb code 9c8v). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the
Human Dna Polymerase Alpha/Primase - Chapso (4 Mm), PDB code: 9c8v:
Jump to Iron binding site number:
1;
2;
3;
4;
Iron binding site 1 out
of 4 in 9c8v
Go back to
Iron Binding Sites List in 9c8v
Iron binding site 1 out
of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Fe601
b:0.7
occ:1.00
|
FE1
|
B:SF4601
|
0.0
|
0.7
|
1.0
|
SG
|
B:CYS367
|
2.3
|
0.8
|
1.0
|
S4
|
B:SF4601
|
2.3
|
6.9
|
1.0
|
S3
|
B:SF4601
|
2.3
|
6.3
|
1.0
|
S2
|
B:SF4601
|
2.3
|
5.7
|
1.0
|
FE3
|
B:SF4601
|
2.7
|
11.6
|
1.0
|
FE2
|
B:SF4601
|
2.7
|
11.2
|
1.0
|
FE4
|
B:SF4601
|
2.7
|
2.6
|
1.0
|
CB
|
B:CYS367
|
3.8
|
0.9
|
1.0
|
S1
|
B:SF4601
|
3.9
|
18.1
|
1.0
|
CA
|
B:CYS367
|
4.3
|
0.5
|
1.0
|
CD1
|
B:LEU441
|
4.5
|
5.3
|
1.0
|
CG
|
B:PRO444
|
4.6
|
1.4
|
1.0
|
SG
|
B:CYS424
|
4.7
|
5.2
|
1.0
|
SG
|
B:CYS384
|
4.8
|
4.7
|
1.0
|
SG
|
B:CYS287
|
4.8
|
3.4
|
1.0
|
CD
|
B:PRO444
|
5.0
|
1.7
|
1.0
|
|
Iron binding site 2 out
of 4 in 9c8v
Go back to
Iron Binding Sites List in 9c8v
Iron binding site 2 out
of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Fe601
b:11.2
occ:1.00
|
FE2
|
B:SF4601
|
0.0
|
11.2
|
1.0
|
SG
|
B:CYS384
|
2.3
|
4.7
|
1.0
|
S3
|
B:SF4601
|
2.3
|
6.3
|
1.0
|
S1
|
B:SF4601
|
2.3
|
18.1
|
1.0
|
S4
|
B:SF4601
|
2.3
|
6.9
|
1.0
|
FE4
|
B:SF4601
|
2.7
|
2.6
|
1.0
|
FE1
|
B:SF4601
|
2.7
|
0.7
|
1.0
|
FE3
|
B:SF4601
|
2.7
|
11.6
|
1.0
|
CB
|
B:CYS384
|
3.4
|
2.9
|
1.0
|
S2
|
B:SF4601
|
3.9
|
5.7
|
1.0
|
CA
|
B:CYS384
|
4.1
|
2.8
|
1.0
|
CD2
|
B:PHE386
|
4.2
|
4.8
|
1.0
|
CD
|
B:PRO385
|
4.5
|
5.5
|
1.0
|
SG
|
B:CYS287
|
4.7
|
3.4
|
1.0
|
CE2
|
B:PHE386
|
4.7
|
7.1
|
1.0
|
SG
|
B:CYS367
|
4.7
|
0.8
|
1.0
|
C
|
B:CYS384
|
4.8
|
3.7
|
1.0
|
SG
|
B:CYS424
|
4.8
|
5.2
|
1.0
|
N
|
B:PRO385
|
4.9
|
2.9
|
1.0
|
|
Iron binding site 3 out
of 4 in 9c8v
Go back to
Iron Binding Sites List in 9c8v
Iron binding site 3 out
of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Fe601
b:11.6
occ:1.00
|
FE3
|
B:SF4601
|
0.0
|
11.6
|
1.0
|
SG
|
B:CYS424
|
2.3
|
5.2
|
1.0
|
S2
|
B:SF4601
|
2.3
|
5.7
|
1.0
|
S4
|
B:SF4601
|
2.3
|
6.9
|
1.0
|
S1
|
B:SF4601
|
2.3
|
18.1
|
1.0
|
FE1
|
B:SF4601
|
2.7
|
0.7
|
1.0
|
FE4
|
B:SF4601
|
2.7
|
2.6
|
1.0
|
FE2
|
B:SF4601
|
2.7
|
11.2
|
1.0
|
CB
|
B:CYS424
|
3.1
|
7.9
|
1.0
|
S3
|
B:SF4601
|
3.9
|
6.3
|
1.0
|
CE2
|
B:PHE386
|
4.3
|
7.1
|
1.0
|
CA
|
B:CYS424
|
4.5
|
9.1
|
1.0
|
CD2
|
B:PHE386
|
4.5
|
4.8
|
1.0
|
CD
|
B:PRO286
|
4.6
|
6.1
|
1.0
|
SG
|
B:CYS367
|
4.7
|
0.8
|
1.0
|
SG
|
B:CYS287
|
4.8
|
3.4
|
1.0
|
SG
|
B:CYS384
|
4.8
|
4.7
|
1.0
|
CD1
|
B:LEU441
|
4.8
|
5.3
|
1.0
|
CB
|
B:PRO285
|
4.8
|
4.4
|
1.0
|
|
Iron binding site 4 out
of 4 in 9c8v
Go back to
Iron Binding Sites List in 9c8v
Iron binding site 4 out
of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Fe601
b:2.6
occ:1.00
|
FE4
|
B:SF4601
|
0.0
|
2.6
|
1.0
|
SG
|
B:CYS287
|
2.3
|
3.4
|
1.0
|
S2
|
B:SF4601
|
2.3
|
5.7
|
1.0
|
S3
|
B:SF4601
|
2.3
|
6.3
|
1.0
|
S1
|
B:SF4601
|
2.3
|
18.1
|
1.0
|
FE2
|
B:SF4601
|
2.7
|
11.2
|
1.0
|
FE1
|
B:SF4601
|
2.7
|
0.7
|
1.0
|
FE3
|
B:SF4601
|
2.7
|
11.6
|
1.0
|
CB
|
B:CYS287
|
3.7
|
5.3
|
1.0
|
S4
|
B:SF4601
|
3.9
|
6.9
|
1.0
|
N
|
B:CYS287
|
4.3
|
9.0
|
1.0
|
CB
|
B:PRO285
|
4.4
|
4.4
|
1.0
|
SG
|
B:CYS384
|
4.6
|
4.7
|
1.0
|
CA
|
B:CYS287
|
4.6
|
7.2
|
1.0
|
CG
|
B:PRO444
|
4.7
|
1.4
|
1.0
|
CD
|
B:PRO385
|
4.8
|
5.5
|
1.0
|
SG
|
B:CYS424
|
4.8
|
5.2
|
1.0
|
SG
|
B:CYS367
|
4.8
|
0.8
|
1.0
|
CG
|
B:PRO285
|
4.9
|
4.1
|
1.0
|
CD
|
B:PRO286
|
5.0
|
6.1
|
1.0
|
|
Reference:
K.M.Abe,
G.Li,
Q.He,
T.Grant,
C.Lim.
Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) To Be Published.
Page generated: Sat Sep 28 21:54:55 2024
|