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Iron in PDB 9c8v: Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)

Enzymatic activity of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)

All present enzymatic activity of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm):
2.7.7.102; 2.7.7.7;

Other elements in 9c8v:

The structure of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) also contains other interesting chemical elements:

Zinc (Zn) 3 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) (pdb code 9c8v). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm), PDB code: 9c8v:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 9c8v

Go back to Iron Binding Sites List in 9c8v
Iron binding site 1 out of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Fe601

b:0.7
occ:1.00
FE1 B:SF4601 0.0 0.7 1.0
SG B:CYS367 2.3 0.8 1.0
S4 B:SF4601 2.3 6.9 1.0
S3 B:SF4601 2.3 6.3 1.0
S2 B:SF4601 2.3 5.7 1.0
FE3 B:SF4601 2.7 11.6 1.0
FE2 B:SF4601 2.7 11.2 1.0
FE4 B:SF4601 2.7 2.6 1.0
CB B:CYS367 3.8 0.9 1.0
S1 B:SF4601 3.9 18.1 1.0
CA B:CYS367 4.3 0.5 1.0
CD1 B:LEU441 4.5 5.3 1.0
CG B:PRO444 4.6 1.4 1.0
SG B:CYS424 4.7 5.2 1.0
SG B:CYS384 4.8 4.7 1.0
SG B:CYS287 4.8 3.4 1.0
CD B:PRO444 5.0 1.7 1.0

Iron binding site 2 out of 4 in 9c8v

Go back to Iron Binding Sites List in 9c8v
Iron binding site 2 out of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Fe601

b:11.2
occ:1.00
FE2 B:SF4601 0.0 11.2 1.0
SG B:CYS384 2.3 4.7 1.0
S3 B:SF4601 2.3 6.3 1.0
S1 B:SF4601 2.3 18.1 1.0
S4 B:SF4601 2.3 6.9 1.0
FE4 B:SF4601 2.7 2.6 1.0
FE1 B:SF4601 2.7 0.7 1.0
FE3 B:SF4601 2.7 11.6 1.0
CB B:CYS384 3.4 2.9 1.0
S2 B:SF4601 3.9 5.7 1.0
CA B:CYS384 4.1 2.8 1.0
CD2 B:PHE386 4.2 4.8 1.0
CD B:PRO385 4.5 5.5 1.0
SG B:CYS287 4.7 3.4 1.0
CE2 B:PHE386 4.7 7.1 1.0
SG B:CYS367 4.7 0.8 1.0
C B:CYS384 4.8 3.7 1.0
SG B:CYS424 4.8 5.2 1.0
N B:PRO385 4.9 2.9 1.0

Iron binding site 3 out of 4 in 9c8v

Go back to Iron Binding Sites List in 9c8v
Iron binding site 3 out of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Fe601

b:11.6
occ:1.00
FE3 B:SF4601 0.0 11.6 1.0
SG B:CYS424 2.3 5.2 1.0
S2 B:SF4601 2.3 5.7 1.0
S4 B:SF4601 2.3 6.9 1.0
S1 B:SF4601 2.3 18.1 1.0
FE1 B:SF4601 2.7 0.7 1.0
FE4 B:SF4601 2.7 2.6 1.0
FE2 B:SF4601 2.7 11.2 1.0
CB B:CYS424 3.1 7.9 1.0
S3 B:SF4601 3.9 6.3 1.0
CE2 B:PHE386 4.3 7.1 1.0
CA B:CYS424 4.5 9.1 1.0
CD2 B:PHE386 4.5 4.8 1.0
CD B:PRO286 4.6 6.1 1.0
SG B:CYS367 4.7 0.8 1.0
SG B:CYS287 4.8 3.4 1.0
SG B:CYS384 4.8 4.7 1.0
CD1 B:LEU441 4.8 5.3 1.0
CB B:PRO285 4.8 4.4 1.0

Iron binding site 4 out of 4 in 9c8v

Go back to Iron Binding Sites List in 9c8v
Iron binding site 4 out of 4 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Fe601

b:2.6
occ:1.00
FE4 B:SF4601 0.0 2.6 1.0
SG B:CYS287 2.3 3.4 1.0
S2 B:SF4601 2.3 5.7 1.0
S3 B:SF4601 2.3 6.3 1.0
S1 B:SF4601 2.3 18.1 1.0
FE2 B:SF4601 2.7 11.2 1.0
FE1 B:SF4601 2.7 0.7 1.0
FE3 B:SF4601 2.7 11.6 1.0
CB B:CYS287 3.7 5.3 1.0
S4 B:SF4601 3.9 6.9 1.0
N B:CYS287 4.3 9.0 1.0
CB B:PRO285 4.4 4.4 1.0
SG B:CYS384 4.6 4.7 1.0
CA B:CYS287 4.6 7.2 1.0
CG B:PRO444 4.7 1.4 1.0
CD B:PRO385 4.8 5.5 1.0
SG B:CYS424 4.8 5.2 1.0
SG B:CYS367 4.8 0.8 1.0
CG B:PRO285 4.9 4.1 1.0
CD B:PRO286 5.0 6.1 1.0

Reference:

K.M.Abe, G.Li, Q.He, T.Grant, C.Lim. Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) To Be Published.
Page generated: Sat Sep 28 21:54:55 2024

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