Iron in PDB 9cmf: Substrate Bound Dosp

All present enzymatic activity of Substrate Bound Dosp:
3.1.4.52;

The structure of Substrate Bound Dosp also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Iron atom in the Substrate Bound Dosp (pdb code 9cmf). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Substrate Bound Dosp, PDB code: 9cmf:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Substrate Bound Dosp


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Substrate Bound Dosp within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe901 b:65.4 occ:1.00 FE A:HEM901 0.0 65.4 1.0 NB A:HEM901 2.0 57.4 1.0 ND A:HEM901 2.1 72.6 1.0 NA A:HEM901 2.1 79.0 1.0 NC A:HEM901 2.1 61.3 1.0 C4A A:HEM901 3.0 81.1 1.0 C1B A:HEM901 3.0 67.3 1.0 C4C A:HEM901 3.0 72.2 1.0 C1D A:HEM901 3.0 73.9 1.0 C4B A:HEM901 3.0 67.2 1.0 C1C A:HEM901 3.1 61.5 1.0 C1A A:HEM901 3.1 77.7 1.0 C4D A:HEM901 3.1 65.0 1.0 NE2 A:HIS77 3.1 124.4 1.0 CHB A:HEM901 3.4 76.9 1.0 CHD A:HEM901 3.4 79.2 1.0 CHC A:HEM901 3.4 72.6 1.0 CHA A:HEM901 3.5 70.7 1.0 O2 A:OXY902 3.6 92.9 1.0 O1 A:OXY902 3.6 92.3 1.0 CD2 A:HIS77 3.7 124.8 1.0 NH2 A:ARG97 4.0 80.4 1.0 C3A A:HEM901 4.2 80.9 1.0 C3C A:HEM901 4.2 66.9 1.0 C2C A:HEM901 4.2 65.9 1.0 C2A A:HEM901 4.2 82.3 1.0 C2B A:HEM901 4.2 64.6 1.0 CE1 A:HIS77 4.2 125.4 1.0 C3B A:HEM901 4.3 67.4 1.0 C2D A:HEM901 4.3 68.3 1.0 C3D A:HEM901 4.3 68.3 1.0 CG A:HIS77 4.9 126.0 1.0 CD2 A:LEU73 5.0 117.5 1.0

Iron binding site 2 out of 2 in the Substrate Bound Dosp


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Substrate Bound Dosp within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe901 b:83.7 occ:1.00 FE B:HEM901 0.0 83.7 1.0 ND B:HEM901 2.0 77.7 1.0 NB B:HEM901 2.0 75.6 1.0 NC B:HEM901 2.0 77.9 1.0 NA B:HEM901 2.0 79.2 1.0 NE2 B:HIS77 2.9 121.5 1.0 C4B B:HEM901 3.0 79.8 1.0 C4D B:HEM901 3.0 80.7 1.0 C1C B:HEM901 3.0 79.6 1.0 C1D B:HEM901 3.0 80.6 1.0 C1B B:HEM901 3.0 78.5 1.0 C1A B:HEM901 3.1 79.5 1.0 C4A B:HEM901 3.1 82.3 1.0 C4C B:HEM901 3.1 75.2 1.0 O2 B:OXY902 3.2 114.9 1.0 O1 B:OXY902 3.3 112.1 1.0 CHC B:HEM901 3.4 80.6 1.0 CHA B:HEM901 3.4 81.0 1.0 CHD B:HEM901 3.4 81.0 1.0 CHB B:HEM901 3.4 83.7 1.0 CD2 B:HIS77 3.6 119.2 1.0 CE1 B:HIS77 4.0 119.4 1.0 C3B B:HEM901 4.2 86.0 1.0 C2D B:HEM901 4.2 84.5 1.0 C2B B:HEM901 4.2 83.7 1.0 C3D B:HEM901 4.2 84.5 1.0 C2C B:HEM901 4.3 79.1 1.0 C3C B:HEM901 4.3 76.3 1.0 C2A B:HEM901 4.3 83.9 1.0 C3A B:HEM901 4.3 83.5 1.0 CG B:HIS77 4.8 121.7 1.0 ND1 B:HIS77 5.0 121.4 1.0

W.Wu, P.Kumar, C.A.Brautigam, S.C.Tso, H.R.Baniasadi, D.L.Kober, M.A.Gilles-Gonzalez. Structures of the Multi-Domain Oxygen Sensor Dosp: Remote Control of A C-Di-Gmp Phosphodiesterase By A Regulatory Pas Domain Nat Commun V. 15 9653 2024.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-024-53942-7