Iron in PDB 28lw: Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens

All present enzymatic activity of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens:
1.2.7.4;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Iron atom in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens (pdb code 28lw). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 12 binding sites of Iron where determined in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens, PDB code: 28lw:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:108.8 occ:1.00 FE1 A:SF4801 0.0 108.8 1.0 SG A:CYS137 2.3 98.0 1.0 S4 A:SF4801 2.3 103.9 1.0 S2 A:SF4801 2.3 104.4 1.0 S3 A:SF4801 2.3 95.0 1.0 FE4 A:SF4801 2.7 107.6 1.0 FE2 A:SF4801 2.7 113.7 1.0 FE3 A:SF4801 2.7 99.4 1.0 CB A:CYS137 3.3 96.2 1.0 S1 A:SF4801 3.9 101.0 1.0 N A:VAL147 4.1 94.0 1.0 N A:CYS137 4.2 92.3 1.0 CA A:GLY135 4.2 93.3 1.0 CA A:CYS137 4.4 95.2 1.0 CA A:GLY146 4.4 89.0 1.0 N A:GLY135 4.5 93.1 1.0 SG A:CYS132 4.6 94.7 1.0 CB A:CYS129 4.6 92.7 1.0 C A:GLY146 4.7 95.5 1.0 SG A:CYS129 4.7 99.8 1.0 SG A:CYS148 4.8 101.6 1.0 O A:CYS129 4.8 97.3 1.0 N A:CYS148 4.8 90.1 1.0 CB A:VAL147 4.8 94.1 1.0 C A:PRO136 4.9 93.0 1.0 C A:MET134 4.9 91.3 1.0 CA A:VAL147 5.0 93.5 1.0

Iron binding site 2 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:113.7 occ:1.00 FE2 A:SF4801 0.0 113.7 1.0 SG A:CYS132 2.2 94.7 1.0 S3 A:SF4801 2.3 95.0 1.0 S4 A:SF4801 2.3 103.9 1.0 S1 A:SF4801 2.3 101.0 1.0 FE4 A:SF4801 2.7 107.6 1.0 FE3 A:SF4801 2.7 99.4 1.0 FE1 A:SF4801 2.7 108.8 1.0 CB A:CYS132 3.3 88.6 1.0 N A:CYS132 3.7 89.1 1.0 S2 A:SF4801 3.9 104.4 1.0 CA A:CYS132 3.9 87.5 1.0 C A:CYS132 4.2 89.9 1.0 O A:CYS132 4.2 91.6 1.0 SG A:CYS277 4.4 105.5 1.0 CB A:CYS277 4.5 92.6 1.0 N A:GLY135 4.5 93.1 1.0 SG A:CYS148 4.7 101.6 1.0 CB A:MET134 4.8 92.5 1.0 SG A:CYS129 4.8 99.8 1.0 C A:ILE131 4.8 90.4 1.0 SG A:CYS137 4.8 98.0 1.0 CE A:MET134 4.9 96.4 1.0 N A:MET134 4.9 96.4 1.0 CA A:GLY135 5.0 93.3 1.0 CB A:CYS148 5.0 92.9 1.0 CB A:ILE131 5.0 86.6 1.0 C A:MET134 5.0 91.3 1.0

Iron binding site 3 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:99.4 occ:1.00 FE3 A:SF4801 0.0 99.4 1.0 SG A:CYS148 2.3 101.6 1.0 S2 A:SF4801 2.3 104.4 1.0 S4 A:SF4801 2.3 103.9 1.0 S1 A:SF4801 2.3 101.0 1.0 FE2 A:SF4801 2.7 113.7 1.0 FE1 A:SF4801 2.7 108.8 1.0 FE4 A:SF4801 2.7 107.6 1.0 CB A:CYS148 3.3 92.9 1.0 S3 A:SF4801 3.9 95.0 1.0 N A:CYS148 3.9 90.1 1.0 CA A:CYS148 4.2 90.4 1.0 NH2 A:ARG158 4.2 92.8 1.0 CB A:ALA150 4.5 92.5 1.0 SG A:CYS277 4.6 105.5 1.0 SG A:CYS132 4.7 94.7 1.0 N A:VAL147 4.7 94.0 1.0 SG A:CYS137 4.7 98.0 1.0 SG A:CYS129 4.8 99.8 1.0 NH1 A:ARG158 4.9 84.7 1.0 C A:CYS148 5.0 92.4 1.0 N A:GLY149 5.0 85.7 1.0 C A:GLY146 5.0 95.5 1.0 CA A:GLY146 5.0 89.0 1.0

Iron binding site 4 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:107.6 occ:1.00 FE4 A:SF4801 0.0 107.6 1.0 SG A:CYS129 2.3 99.8 1.0 S3 A:SF4801 2.3 95.0 1.0 S2 A:SF4801 2.3 104.4 1.0 S1 A:SF4801 2.3 101.0 1.0 FE2 A:SF4801 2.7 113.7 1.0 FE1 A:SF4801 2.7 108.8 1.0 FE3 A:SF4801 2.7 99.4 1.0 CB A:CYS129 3.1 92.7 1.0 NH2 A:ARG158 3.7 92.8 1.0 S4 A:SF4801 3.9 103.9 1.0 CA A:CYS129 4.3 91.1 1.0 C A:CYS129 4.3 91.7 1.0 CB A:ILE131 4.3 86.6 1.0 N A:ILE131 4.3 88.2 1.0 O A:CYS129 4.4 97.3 1.0 CZ A:ARG158 4.6 83.4 1.0 N A:CYS132 4.7 89.1 1.0 SG A:CYS137 4.8 98.0 1.0 SG A:CYS148 4.8 101.6 1.0 CA A:ILE131 4.9 86.8 1.0 N A:LYS130 4.9 87.0 1.0 SG A:CYS132 4.9 94.7 1.0 NH1 A:ARG158 4.9 84.7 1.0 CG1 A:ILE131 5.0 86.7 1.0

Iron binding site 5 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe801 b:123.5 occ:1.00 FE1 B:SF4801 0.0 123.5 1.0 SG A:CYS128 2.2 93.6 1.0 S4 B:SF4801 2.3 114.1 1.0 S2 B:SF4801 2.3 117.0 1.0 S3 B:SF4801 2.3 106.1 1.0 FE4 B:SF4801 2.7 131.3 1.0 FE3 B:SF4801 2.7 122.3 1.0 FE2 B:SF4801 2.7 118.2 1.0 CB A:CYS128 3.1 87.2 1.0 S1 B:SF4801 3.9 116.5 1.0 SG B:CYS128 4.5 100.0 1.0 CA A:CYS128 4.5 87.0 1.0 CD A:LYS130 4.5 90.9 1.0 SG A:CYS120 4.6 109.8 1.0 CD B:LYS130 4.7 90.1 1.0 SG B:CYS120 4.7 109.4 1.0

Iron binding site 6 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe801 b:118.2 occ:1.00 FE2 B:SF4801 0.0 118.2 1.0 SG A:CYS120 2.3 109.8 1.0 S1 B:SF4801 2.3 116.5 1.0 S3 B:SF4801 2.3 106.1 1.0 S4 B:SF4801 2.3 114.1 1.0 FE3 B:SF4801 2.7 122.3 1.0 FE4 B:SF4801 2.7 131.3 1.0 FE1 B:SF4801 2.7 123.5 1.0 CB A:CYS120 3.0 103.5 1.0 S2 B:SF4801 3.9 117.0 1.0 N A:GLY123 4.3 96.2 1.0 CA A:CYS120 4.5 100.7 1.0 CB A:PHE122 4.6 92.8 1.0 SG B:CYS120 4.7 109.4 1.0 CA A:GLY123 4.8 92.5 1.0 SG B:CYS128 4.8 100.0 1.0 SG A:CYS128 4.8 93.6 1.0 CB A:CYS128 5.0 87.2 1.0

Iron binding site 7 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe801 b:122.3 occ:1.00 FE3 B:SF4801 0.0 122.3 1.0 SG B:CYS120 2.2 109.4 1.0 S4 B:SF4801 2.3 114.1 1.0 S2 B:SF4801 2.3 117.0 1.0 S1 B:SF4801 2.3 116.5 1.0 FE2 B:SF4801 2.7 118.2 1.0 FE1 B:SF4801 2.7 123.5 1.0 FE4 B:SF4801 2.7 131.3 1.0 CB B:CYS120 3.4 92.6 1.0 S3 B:SF4801 3.9 106.1 1.0 N B:GLY123 4.2 97.2 1.0 CB B:PHE122 4.3 98.2 1.0 CD2 B:PHE122 4.4 102.7 1.0 SG A:CYS120 4.6 109.8 1.0 SG A:CYS128 4.7 93.6 1.0 CA B:CYS120 4.8 93.0 1.0 NH1 A:ARG138 4.8 107.6 1.0 CG B:PHE122 4.8 99.5 1.0 SG B:CYS128 4.8 100.0 1.0 N B:PHE122 4.9 93.1 1.0 CA B:GLY123 4.9 96.5 1.0 CB B:CYS128 4.9 89.5 1.0 CA B:PHE122 5.0 95.0 1.0 C B:PHE122 5.0 98.8 1.0

Iron binding site 8 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe801 b:131.3 occ:1.00 FE4 B:SF4801 0.0 131.3 1.0 SG B:CYS128 2.2 100.0 1.0 S3 B:SF4801 2.3 106.1 1.0 S1 B:SF4801 2.3 116.5 1.0 S2 B:SF4801 2.3 117.0 1.0 FE1 B:SF4801 2.7 123.5 1.0 FE2 B:SF4801 2.7 118.2 1.0 FE3 B:SF4801 2.7 122.3 1.0 CB B:CYS128 3.0 89.5 1.0 S4 B:SF4801 3.9 114.1 1.0 CA B:CYS128 4.4 88.7 1.0 CB B:PHE122 4.6 98.2 1.0 SG A:CYS128 4.7 93.6 1.0 CD A:LYS130 4.7 90.9 1.0 CD B:LYS130 4.8 90.1 1.0 SG B:CYS120 4.8 109.4 1.0 N B:GLY123 4.8 97.2 1.0 SG A:CYS120 4.9 109.8 1.0 CG B:LYS130 4.9 90.1 1.0

Iron binding site 9 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe802 b:110.5 occ:1.00 FE1 B:SF4802 0.0 110.5 1.0 SG B:CYS129 2.3 93.9 1.0 S4 B:SF4802 2.3 98.9 1.0 S2 B:SF4802 2.3 117.9 1.0 S3 B:SF4802 2.3 101.4 1.0 FE3 B:SF4802 2.7 109.2 1.0 FE2 B:SF4802 2.7 109.5 1.0 FE4 B:SF4802 2.7 110.9 1.0 CB B:CYS129 3.2 89.2 1.0 S1 B:SF4802 3.9 115.1 1.0 NH2 B:ARG158 4.1 97.6 1.0 O B:CYS129 4.1 94.7 1.0 C B:CYS129 4.3 89.2 1.0 CB B:ILE131 4.3 88.3 1.0 CA B:CYS129 4.4 91.9 1.0 N B:ILE131 4.4 88.0 1.0 NH1 B:ARG158 4.5 96.0 1.0 CZ B:ARG158 4.7 94.6 1.0 SG B:CYS137 4.7 97.6 1.0 SG B:CYS148 4.8 100.4 1.0 N B:CYS132 4.8 88.9 1.0 CB B:CYS137 4.8 98.3 1.0 CD1 B:ILE131 4.9 90.8 1.0 SG B:CYS132 4.9 96.2 1.0 CA B:ILE131 4.9 88.4 1.0 CG1 B:ILE131 5.0 91.3 1.0 N B:LYS130 5.0 85.0 1.0

Iron binding site 10 out of 12 in the Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Cryoem Structure of Carbon Monoxide Dehydrogenase From Ruminococcus Flavefaciens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe802 b:109.5 occ:1.00 FE2 B:SF4802 0.0 109.5 1.0 SG B:CYS132 2.2 96.2 1.0 S3 B:SF4802 2.3 101.4 1.0 S4 B:SF4802 2.3 98.9 1.0 S1 B:SF4802 2.3 115.1 1.0 FE4 B:SF4802 2.7 110.9 1.0 FE3 B:SF4802 2.7 109.2 1.0 FE1 B:SF4802 2.7 110.5 1.0 CB B:CYS132 3.4 90.8 1.0 N B:CYS132 3.8 88.9 1.0 S2 B:SF4802 3.9 117.9 1.0 CA B:CYS132 4.0 88.0 1.0 O B:CYS132 4.3 98.5 1.0 C B:CYS132 4.3 93.8 1.0 SG B:CYS277 4.4 110.6 1.0 N B:GLY135 4.6 95.0 1.0 CB B:MET134 4.6 92.9 1.0 SG B:CYS148 4.8 100.4 1.0 CB B:CYS277 4.8 98.3 1.0 SG B:CYS137 4.8 97.6 1.0 SG B:CYS129 4.8 93.9 1.0 C B:ILE131 4.9 91.2 1.0 N B:MET134 4.9 94.5 1.0 CB B:CYS148 4.9 97.2 1.0 C B:MET134 5.0 95.3 1.0 CB B:ILE131 5.0 88.3 1.0

M.Bohm, V.Srinivas, B.Wiseman, P.Huang, M.Senger, M.Hogbom, H.Land. Beyond Canonical Co Oxidation: Structural and Evolutionary Insights Into A Non-Canonical Carbon Monoxide Dehydrogenase. Angew.Chem.Int.Ed.Engl. 02233 2026.
ISSN: ESSN 1521-3773
PubMed: 42495917
DOI: 10.1002/ANIE.1702233