Iron in PDB 9i6f: Cryo-Em Structure of HIGD2A Bound Complex IV

All present enzymatic activity of Cryo-Em Structure of HIGD2A Bound Complex IV:
7.1.1.9;

The structure of Cryo-Em Structure of HIGD2A Bound Complex IV also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Copper	(Cu)	3 atoms
Zinc	(Zn)	1 atom

The binding sites of Iron atom in the Cryo-Em Structure of HIGD2A Bound Complex IV (pdb code 9i6f). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Cryo-Em Structure of HIGD2A Bound Complex IV, PDB code: 9i6f:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Cryo-Em Structure of HIGD2A Bound Complex IV


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of HIGD2A Bound Complex IV within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe604 b:67.1 occ:1.00 FE A:HEA604 0.0 67.1 1.0 NA A:HEA604 2.0 51.1 1.0 NC A:HEA604 2.1 50.6 1.0 NB A:HEA604 2.1 54.3 1.0 ND A:HEA604 2.1 44.6 1.0 NE2 A:HIS61 2.3 48.1 1.0 NE2 A:HIS378 2.3 40.3 1.0 HD2 A:HIS61 3.0 49.9 1.0 CD2 A:HIS61 3.0 47.4 1.0 C4A A:HEA604 3.1 47.0 1.0 C1A A:HEA604 3.1 43.6 1.0 C4C A:HEA604 3.1 42.0 1.0 C1D A:HEA604 3.1 43.8 1.0 C1B A:HEA604 3.1 47.4 1.0 C1C A:HEA604 3.1 46.8 1.0 C4B A:HEA604 3.1 47.7 1.0 C4D A:HEA604 3.1 43.1 1.0 CD2 A:HIS378 3.2 45.0 1.0 HD2 A:HIS378 3.3 46.6 1.0 CE1 A:HIS378 3.4 50.6 1.0 CE1 A:HIS61 3.5 60.5 1.0 CHB A:HEA604 3.5 49.0 1.0 CHD A:HEA604 3.5 36.6 1.0 CHC A:HEA604 3.5 45.5 1.0 CHA A:HEA604 3.5 40.7 1.0 HE1 A:HIS378 3.6 52.0 1.0 HE1 A:HIS61 3.8 62.0 1.0 CG A:HIS61 4.3 42.7 1.0 C3A A:HEA604 4.3 42.2 1.0 C2A A:HEA604 4.4 40.8 1.0 CG A:HIS378 4.4 52.9 1.0 C3C A:HEA604 4.4 43.7 1.0 ND1 A:HIS61 4.4 53.6 1.0 ND1 A:HIS378 4.4 51.0 1.0 C2B A:HEA604 4.5 45.3 1.0 C2D A:HEA604 4.5 41.1 1.0 HE2 A:PHE377 4.5 52.7 1.0 C3B A:HEA604 4.5 48.5 1.0 C3D A:HEA604 4.5 44.0 1.0 C2C A:HEA604 4.5 48.0 1.0 HHB A:HEA604 4.5 52.2 1.0 HHD A:HEA604 4.5 42.2 1.0 HHA A:HEA604 4.5 45.8 1.0 HHC A:HEA604 4.5 50.9 1.0 HZ A:PHE425 4.7 57.9 1.0 HE1 A:PHE425 5.0 59.6 1.0

Iron binding site 2 out of 2 in the Cryo-Em Structure of HIGD2A Bound Complex IV


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of HIGD2A Bound Complex IV within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe605 b:70.0 occ:1.00 FE A:HEA605 0.0 70.0 1.0 NA A:HEA605 2.0 49.5 1.0 NC A:HEA605 2.1 48.8 1.0 NB A:HEA605 2.1 52.9 1.0 ND A:HEA605 2.1 51.6 1.0 NE2 A:HIS376 2.5 48.0 1.0 C1A A:HEA605 3.1 45.8 1.0 C4A A:HEA605 3.1 40.8 1.0 HD2 A:HIS376 3.1 52.5 1.0 C4C A:HEA605 3.1 50.4 1.0 C1C A:HEA605 3.1 50.7 1.0 C4B A:HEA605 3.1 58.3 1.0 C1D A:HEA605 3.1 49.1 1.0 C1B A:HEA605 3.1 48.3 1.0 C4D A:HEA605 3.1 51.8 1.0 CD2 A:HIS376 3.2 50.2 1.0 CHC A:HEA605 3.5 60.5 1.0 CHA A:HEA605 3.5 51.1 1.0 CHD A:HEA605 3.5 46.3 1.0 CHB A:HEA605 3.5 45.7 1.0 CE1 A:HIS376 3.6 52.2 1.0 HE1 A:HIS376 4.0 59.3 1.0 HE1 A:HIS240 4.0 60.5 1.0 CU A:CU601 4.2 114.8 1.0 C3A A:HEA605 4.3 42.6 1.0 C2A A:HEA605 4.4 43.9 1.0 HE1 A:HIS291 4.4 52.8 1.0 CG A:HIS376 4.4 52.0 1.0 C3C A:HEA605 4.4 51.2 1.0 C2B A:HEA605 4.5 53.8 1.0 C3B A:HEA605 4.5 59.9 1.0 C2D A:HEA605 4.5 41.4 1.0 C2C A:HEA605 4.5 48.8 1.0 C3D A:HEA605 4.5 46.2 1.0 HHC A:HEA605 4.5 58.6 1.0 HHA A:HEA605 4.5 50.9 1.0 HHD A:HEA605 4.5 47.9 1.0 HHB A:HEA605 4.5 55.3 1.0 HG22 A:VAL243 4.5 60.5 1.0 ND1 A:HIS376 4.6 57.9 1.0 CE1 A:HIS240 4.8 59.5 1.0 HG12 A:VAL243 4.9 56.1 1.0

M.D.Nguyen, V.Singh, J.Rorbach. Structural Basis For Late Maturation Steps of Mitochondrial Respiratory Chain Complex IV Within the Human Respirasome To Be Published.