Iron in PDB 9i7u: Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex

All present enzymatic activity of Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex:
7.1.1.9;

The structure of Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex also contains other interesting chemical elements:

Zinc	(Zn)	1 atom
Magnesium	(Mg)	1 atom
Copper	(Cu)	3 atoms

The binding sites of Iron atom in the Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex (pdb code 9i7u). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex, PDB code: 9i7u:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe604 b:72.8 occ:1.00 FE A:HEA604 0.0 72.8 1.0 NA A:HEA604 2.0 60.0 1.0 NC A:HEA604 2.1 40.7 1.0 ND A:HEA604 2.1 64.3 1.0 NB A:HEA604 2.1 60.3 1.0 C4A A:HEA604 3.0 41.4 1.0 C1A A:HEA604 3.0 44.0 1.0 C1D A:HEA604 3.1 51.5 1.0 C1C A:HEA604 3.1 43.0 1.0 C4B A:HEA604 3.1 63.1 1.0 C4C A:HEA604 3.1 53.5 1.0 C4D A:HEA604 3.1 73.8 1.0 C1B A:HEA604 3.1 55.5 1.0 NE2 A:HIS376 3.2 45.7 1.0 HD2 A:HIS376 3.3 53.0 1.0 CHA A:HEA604 3.5 63.9 1.0 CHB A:HEA604 3.5 44.0 1.0 CHD A:HEA604 3.5 55.3 1.0 CHC A:HEA604 3.5 47.6 1.0 CD2 A:HIS376 3.5 48.6 1.0 HE1 A:HIS240 3.7 58.8 1.0 C3A A:HEA604 4.2 34.9 1.0 C2A A:HEA604 4.3 38.8 1.0 CE1 A:HIS376 4.3 53.8 1.0 HE1 A:HIS291 4.3 54.5 1.0 HE1 A:HIS290 4.4 60.6 1.0 C3C A:HEA604 4.4 80.8 1.0 HHA A:HEA604 4.4 58.3 1.0 C2D A:HEA604 4.4 53.8 1.0 C3B A:HEA604 4.4 66.4 1.0 C2C A:HEA604 4.4 74.0 1.0 C2B A:HEA604 4.4 52.5 1.0 HHB A:HEA604 4.4 45.9 1.0 HHD A:HEA604 4.4 62.1 1.0 C3D A:HEA604 4.5 63.4 1.0 HHC A:HEA604 4.5 54.3 1.0 CE1 A:HIS240 4.6 60.0 1.0 CU A:CU601 4.6 111.1 1.0 CG A:HIS376 4.7 45.1 1.0 HE1 A:HIS376 4.7 58.7 1.0 CE1 A:HIS290 4.9 59.2 1.0

Iron binding site 2 out of 2 in the Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of NDUFA4 Bound Complex IV Within the Respirasome Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe605 b:76.7 occ:1.00 FE A:HEA605 0.0 76.7 1.0 HE1 A:HIS378 1.8 54.4 1.0 NA A:HEA605 2.0 61.7 1.0 NC A:HEA605 2.1 54.5 1.0 ND A:HEA605 2.1 40.1 1.0 NB A:HEA605 2.1 58.6 1.0 NE2 A:HIS61 2.3 45.2 1.0 CE1 A:HIS378 2.6 54.7 1.0 C4A A:HEA605 3.0 48.3 1.0 HE1 A:HIS61 3.1 49.8 1.0 CE1 A:HIS61 3.1 47.8 1.0 C4C A:HEA605 3.1 47.9 1.0 C1D A:HEA605 3.1 39.7 1.0 C1A A:HEA605 3.1 50.7 1.0 C1C A:HEA605 3.1 57.2 1.0 C1B A:HEA605 3.1 52.9 1.0 C4D A:HEA605 3.1 42.5 1.0 C4B A:HEA605 3.2 59.0 1.0 NE2 A:HIS378 3.3 52.6 1.0 CHD A:HEA605 3.5 42.2 1.0 CHB A:HEA605 3.5 48.7 1.0 CD2 A:HIS61 3.5 49.3 1.0 CHA A:HEA605 3.5 45.0 1.0 CHC A:HEA605 3.5 61.8 1.0 ND1 A:HIS378 3.7 55.6 1.0 HD2 A:HIS61 3.8 53.3 1.0 HD1 A:HIS378 3.9 57.2 1.0 ND1 A:HIS61 4.3 57.1 1.0 C3A A:HEA605 4.3 43.8 1.0 HG3 A:MET65 4.3 57.6 1.0 C2A A:HEA605 4.4 44.3 1.0 C3C A:HEA605 4.4 53.3 1.0 C2D A:HEA605 4.4 37.4 1.0 C2C A:HEA605 4.5 56.2 1.0 C2B A:HEA605 4.5 54.9 1.0 HHD A:HEA605 4.5 47.2 1.0 HZ A:PHE377 4.5 68.6 1.0 C3D A:HEA605 4.5 42.5 1.0 HHB A:HEA605 4.5 53.2 1.0 HHA A:HEA605 4.5 50.5 1.0 C3B A:HEA605 4.5 58.7 1.0 HHC A:HEA605 4.5 62.8 1.0 CG A:HIS61 4.5 44.8 1.0 CD2 A:HIS378 4.6 54.9 1.0 HE3 A:MET65 4.6 65.7 1.0 HE2 A:PHE377 4.7 59.2 1.0 CG A:HIS378 4.7 50.1 1.0 HB2 A:SER34 4.8 68.8 1.0 HZ A:PHE425 4.9 51.9 1.0 HB3 A:SER34 5.0 68.4 1.0

M.D.Nguyen, J.Rorbach. Structural Basis For Late Maturation Steps of Mitochondrial Respiratory Chain Complex IV Within the Human Respirasome To Be Published.