Iron in PDB 9ihq: Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs

All present enzymatic activity of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs:
1.6.5.3; 7.1.1.2;

The structure of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs also contains other interesting chemical elements:

Potassium	(K)	1 atom
Zinc	(Zn)	1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 22;

Binding sites:

The binding sites of Iron atom in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs (pdb code 9ihq). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 22 binding sites of Iron where determined in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs, PDB code: 9ihq:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:23.3 occ:1.00 FE1 B:SF4301 0.0 23.3 1.0 SG B:CYS143 2.2 13.0 1.0 S4 B:SF4301 2.3 13.8 1.0 S3 B:SF4301 2.3 21.0 1.0 S2 B:SF4301 2.3 17.9 1.0 FE2 B:SF4301 2.7 24.6 1.0 FE4 B:SF4301 2.7 29.0 1.0 FE3 B:SF4301 2.7 27.5 1.0 CB B:CYS143 3.2 12.7 1.0 S1 B:SF4301 3.9 14.2 1.0 N B:CYS143 3.9 12.1 1.0 OG1 B:THR115 3.9 16.6 1.0 CA B:CYS143 4.1 11.3 1.0 CQ1 D:2MR137 4.4 17.4 1.0 SG B:CYS173 4.7 20.3 1.0 CE2 B:TYR150 4.8 7.7 1.0 SG B:CYS78 4.8 22.8 1.0 SG B:CYS79 4.8 20.6 1.0 N B:THR115 4.8 15.9 1.0 NH1 D:2MR137 5.0 19.7 1.0

Iron binding site 2 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:24.6 occ:1.00 FE2 B:SF4301 0.0 24.6 1.0 SG B:CYS173 2.2 20.3 1.0 S3 B:SF4301 2.3 21.0 1.0 S4 B:SF4301 2.3 13.8 1.0 S1 B:SF4301 2.3 14.2 1.0 FE1 B:SF4301 2.7 23.3 1.0 FE3 B:SF4301 2.7 27.5 1.0 FE4 B:SF4301 2.7 29.0 1.0 CB B:CYS173 3.5 14.6 1.0 CA B:CYS173 3.7 15.0 1.0 S2 B:SF4301 3.9 17.9 1.0 C B:CYS173 4.0 17.5 1.0 NE D:ARG157 4.0 13.8 1.0 CD2 D:HIS242 4.4 15.1 1.0 N B:PRO174 4.4 16.4 1.0 NH2 D:ARG157 4.4 15.8 1.0 O B:CYS173 4.5 21.7 1.0 NE2 D:HIS242 4.5 17.1 1.0 SG B:CYS143 4.7 13.0 1.0 CZ D:ARG157 4.7 14.8 1.0 CA B:PRO174 4.7 16.7 1.0 SG B:CYS78 4.8 22.8 1.0 SG B:CYS79 4.8 20.6 1.0 CD D:ARG157 4.9 12.9 1.0 O B:GLY172 4.9 17.1 1.0

Iron binding site 3 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:27.5 occ:1.00 FE3 B:SF4301 0.0 27.5 1.0 SG B:CYS78 2.3 22.8 1.0 S1 B:SF4301 2.3 14.2 1.0 S2 B:SF4301 2.3 17.9 1.0 S4 B:SF4301 2.3 13.8 1.0 FE4 B:SF4301 2.7 29.0 1.0 FE2 B:SF4301 2.7 24.6 1.0 FE1 B:SF4301 2.7 23.3 1.0 CB B:CYS78 3.3 18.8 1.0 NE2 D:HIS242 3.7 17.1 1.0 CQ1 D:2MR137 3.8 17.4 1.0 N B:CYS78 3.9 20.2 1.0 S3 B:SF4301 3.9 21.0 1.0 CA B:CYS78 4.0 17.5 1.0 N B:CYS79 4.0 23.2 1.0 C B:CYS78 4.2 21.7 1.0 CD2 D:HIS242 4.4 15.1 1.0 CG D:ARG157 4.5 15.3 1.0 CB B:ALA77 4.6 22.3 1.0 SG B:CYS143 4.7 13.0 1.0 SG B:CYS173 4.7 20.3 1.0 SG B:CYS79 4.8 20.6 1.0 NE D:ARG157 4.8 13.8 1.0 CE1 D:HIS242 4.8 18.0 1.0 C B:ALA77 4.9 23.7 1.0 CD D:ARG157 5.0 12.9 1.0 CA B:CYS79 5.0 21.1 1.0

Iron binding site 4 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:29.0 occ:1.00 FE4 B:SF4301 0.0 29.0 1.0 SG B:CYS79 2.3 20.6 1.0 S1 B:SF4301 2.3 14.2 1.0 S2 B:SF4301 2.3 17.9 1.0 S3 B:SF4301 2.3 21.0 1.0 FE3 B:SF4301 2.7 27.5 1.0 FE2 B:SF4301 2.7 24.6 1.0 FE1 B:SF4301 2.7 23.3 1.0 CB B:CYS79 3.3 20.2 1.0 N B:CYS79 3.7 23.2 1.0 CA B:CYS79 3.8 21.1 1.0 S4 B:SF4301 3.9 13.8 1.0 CA B:GLY141 4.4 12.7 1.0 CA B:PRO174 4.5 16.7 1.0 CB B:PRO174 4.5 17.9 1.0 C B:CYS78 4.5 21.7 1.0 SG B:CYS143 4.7 13.0 1.0 SG B:CYS173 4.7 20.3 1.0 SG B:CYS78 4.8 22.8 1.0 N B:SER142 4.8 12.3 1.0 CA B:CYS173 4.9 15.0 1.0 N B:PRO174 5.0 16.4 1.0 CB B:CYS143 5.0 12.7 1.0 C B:GLY141 5.0 13.1 1.0

Iron binding site 5 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe801 b:47.7 occ:1.00 FE1 G:SF4801 0.0 47.7 1.0 S2 G:SF4801 2.3 24.8 1.0 S3 G:SF4801 2.3 21.6 1.0 S4 G:SF4801 2.3 39.6 1.0 SG G:CYS173 2.3 27.1 1.0 FE3 G:SF4801 2.7 44.7 1.0 FE4 G:SF4801 2.7 52.8 1.0 FE2 G:SF4801 2.8 42.5 1.0 CB G:CYS173 3.3 18.6 1.0 N G:HIS175 3.8 27.8 1.0 S1 G:SF4801 3.9 38.2 1.0 CA G:CYS173 3.9 15.9 1.0 N G:ILE174 4.1 16.9 1.0 N G:CYS176 4.1 33.3 1.0 CA G:HIS175 4.2 25.4 1.0 C G:CYS173 4.4 16.0 1.0 CE G:MET170 4.7 13.5 1.0 C G:HIS175 4.7 30.6 1.0 C G:ILE174 4.8 22.6 1.0 SG G:CYS179 4.8 43.5 1.0 CB G:ALA227 4.8 9.9 1.0 SG G:CYS223 4.8 18.0 1.0 SG G:CYS176 4.9 32.5 1.0 N G:THR177 4.9 40.2 1.0

Iron binding site 6 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe801 b:42.5 occ:1.00 FE2 G:SF4801 0.0 42.5 1.0 S1 G:SF4801 2.3 38.2 1.0 S3 G:SF4801 2.3 21.6 1.0 S4 G:SF4801 2.3 39.6 1.0 SG G:CYS176 2.3 32.5 1.0 FE4 G:SF4801 2.7 52.8 1.0 FE3 G:SF4801 2.7 44.7 1.0 FE1 G:SF4801 2.8 47.7 1.0 CB G:CYS176 3.3 39.4 1.0 N G:CYS176 3.6 33.3 1.0 N G:THR177 3.7 40.2 1.0 CA G:CYS176 3.8 37.3 1.0 N G:ARG178 3.8 37.4 1.0 C G:CYS176 3.9 37.4 1.0 S2 G:SF4801 3.9 24.8 1.0 CD G:PRO224 4.0 14.0 1.0 CB G:ARG178 4.3 36.4 1.0 CA G:ARG178 4.6 34.1 1.0 CA G:THR177 4.6 41.3 1.0 N G:CYS179 4.6 36.1 1.0 O G:CYS176 4.6 38.9 1.0 C G:THR177 4.7 40.8 1.0 CG G:PRO224 4.8 17.5 1.0 SG G:CYS179 4.8 43.5 1.0 SG G:CYS223 4.8 18.0 1.0 C G:HIS175 4.8 30.6 1.0 SG G:CYS173 4.8 27.1 1.0 CA G:CYS223 4.9 13.5 1.0 N G:HIS175 4.9 27.8 1.0 CG G:ARG178 5.0 38.7 1.0 CG1 G:ILE174 5.0 20.9 1.0

Iron binding site 7 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe801 b:44.7 occ:1.00 FE3 G:SF4801 0.0 44.7 1.0 SG G:CYS179 2.3 43.5 1.0 S1 G:SF4801 2.3 38.2 1.0 S4 G:SF4801 2.3 39.6 1.0 S2 G:SF4801 2.3 24.8 1.0 FE1 G:SF4801 2.7 47.7 1.0 FE2 G:SF4801 2.7 42.5 1.0 FE4 G:SF4801 2.7 52.8 1.0 CB G:CYS179 3.3 38.4 1.0 N G:CYS179 3.6 36.1 1.0 S3 G:SF4801 3.9 21.6 1.0 CA G:CYS179 4.1 37.6 1.0 N G:ARG178 4.3 37.4 1.0 N G:THR177 4.5 40.2 1.0 CA G:THR177 4.7 41.3 1.0 C G:ARG178 4.7 35.0 1.0 CD1 G:LEU228 4.8 13.2 1.0 SG G:CYS173 4.8 27.1 1.0 SG G:CYS223 4.8 18.0 1.0 SG G:CYS176 4.8 32.5 1.0 C G:THR177 4.8 40.8 1.0 CA G:ARG178 5.0 34.1 1.0

Iron binding site 8 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe801 b:52.8 occ:1.00 FE4 G:SF4801 0.0 52.8 1.0 SG G:CYS223 2.3 18.0 1.0 S1 G:SF4801 2.3 38.2 1.0 S3 G:SF4801 2.3 21.6 1.0 S2 G:SF4801 2.3 24.8 1.0 FE2 G:SF4801 2.7 42.5 1.0 FE1 G:SF4801 2.7 47.7 1.0 FE3 G:SF4801 2.7 44.7 1.0 CB G:CYS223 3.3 15.2 1.0 CA G:CYS223 3.7 13.5 1.0 S4 G:SF4801 3.9 39.6 1.0 CD G:PRO224 4.2 14.0 1.0 CB G:ALA227 4.2 9.9 1.0 C G:CYS223 4.5 14.7 1.0 CD1 G:LEU228 4.5 13.2 1.0 CG2 G:VAL225 4.6 9.9 1.0 CG G:LEU228 4.6 12.8 1.0 N G:PRO224 4.7 13.1 1.0 SG G:CYS179 4.8 43.5 1.0 SG G:CYS176 4.8 32.5 1.0 SG G:CYS173 4.8 27.1 1.0 N G:CYS223 4.8 12.4 1.0

Iron binding site 9 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe802 b:12.5 occ:1.00 FE1 G:SF4802 0.0 12.5 1.0 S2 G:SF4802 2.3 1.6 1.0 S4 G:SF4802 2.3 1.3 1.0 S3 G:SF4802 2.3 2.4 1.0 SG G:CYS123 2.3 1.1 1.0 FE3 G:SF4802 2.7 7.6 1.0 FE4 G:SF4802 2.7 2.3 1.0 FE2 G:SF4802 2.7 4.2 1.0 CB G:CYS123 3.3 0.7 1.0 NE2 G:GLN135 3.4 7.4 1.0 CA G:CYS123 3.5 0.9 1.0 CE D:MET394 3.8 24.5 1.0 N G:CYS123 3.8 0.9 1.0 S1 G:SF4802 3.9 7.8 1.0 CG G:GLN135 4.1 5.6 1.0 CD G:GLN135 4.2 7.2 1.0 NE2 G:HIS119 4.4 6.2 1.0 C G:ASP122 4.7 1.1 1.0 CD2 G:HIS119 4.7 5.0 1.0 SG G:CYS126 4.8 1.8 1.0 SG G:CYS132 4.8 9.3 1.0 C G:CYS123 4.9 0.6 1.0 CB G:CYS126 5.0 1.2 1.0

Iron binding site 10 out of 22 in the Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Closed State with Nuqm and Without Flavoprotein (Classification State 2) of Pichia Pastoris Mitochondrial Complex I in CMSP26 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe802 b:4.2 occ:1.00 FE2 G:SF4802 0.0 4.2 1.0 SG G:CYS132 2.3 9.3 1.0 S1 G:SF4802 2.3 7.8 1.0 S4 G:SF4802 2.3 1.3 1.0 S3 G:SF4802 2.3 2.4 1.0 FE3 G:SF4802 2.7 7.6 1.0 FE4 G:SF4802 2.7 2.3 1.0 FE1 G:SF4802 2.7 12.5 1.0 CB G:CYS132 3.3 9.1 1.0 CG G:GLN135 3.9 5.6 1.0 S2 G:SF4802 3.9 1.6 1.0 NE2 G:GLN135 4.4 7.4 1.0 NE2 G:HIS119 4.4 6.2 1.0 CB G:LEU134 4.5 12.8 1.0 CD G:GLN135 4.5 7.2 1.0 N G:GLN135 4.5 16.0 1.0 CA G:CYS132 4.6 6.6 1.0 CB G:GLN128 4.7 3.0 1.0 SG G:CYS126 4.8 1.8 1.0 CB G:GLN135 4.8 7.1 1.0 SG G:CYS123 4.8 1.1 1.0 CD2 G:LEU134 4.8 11.6 1.0 CG1 G:VAL225 4.9 6.5 1.0 CG G:LEU134 5.0 12.9 1.0

C.S.Lee, D.N.Grba, J.J.Wright, B.S.Ivanov, J.Hirst. Global Conformations of Pichia Pastoris Complex I Are Distinguished By the Binding of A Unique Interdomain Bridging Subunit. Sci Adv V. 11 Z0693 2025.
ISSN: ESSN 2375-2548
PubMed: 41032597
DOI: 10.1126/SCIADV.ADZ0693