Iron in PDB 1phb: Inhibitor-Induced Conformational Change in Cytochrome P450-Cam

All present enzymatic activity of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam:
1.14.15.1;

The structure of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam, PDB code: 1phb was solved by T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	108.670, 103.900, 36.380, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The structure of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Iron atom in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam (pdb code 1phb). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam, PDB code: 1phb:

Iron binding site 1 out of 1 in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe417 b:12.8 occ:1.00 FE A:HEM417 0.0 12.8 1.0 ND A:HEM417 2.0 12.6 1.0 SG A:CYS357 2.0 11.0 1.0 N19 A:PFZ422 2.0 23.8 1.0 NB A:HEM417 2.0 13.1 1.0 NA A:HEM417 2.0 12.9 1.0 NC A:HEM417 2.0 13.3 1.0 C18 A:PFZ422 2.6 25.5 1.0 C4C A:HEM417 3.0 13.2 1.0 C4D A:HEM417 3.1 13.4 1.0 C1A A:HEM417 3.1 11.6 1.0 C1D A:HEM417 3.1 13.6 1.0 C1C A:HEM417 3.1 12.7 1.0 C4A A:HEM417 3.1 12.5 1.0 C4B A:HEM417 3.1 13.1 1.0 C1B A:HEM417 3.1 13.0 1.0 C20 A:PFZ422 3.3 26.1 1.0 CB A:CYS357 3.4 14.0 1.0 CHD A:HEM417 3.4 12.7 1.0 CHA A:HEM417 3.4 12.1 1.0 CHC A:HEM417 3.4 13.3 1.0 CHB A:HEM417 3.5 12.5 1.0 C17 A:PFZ422 3.9 25.1 1.0 CA A:CYS357 4.0 13.3 1.0 N11 A:PFZ422 4.2 25.4 1.0 C3D A:HEM417 4.3 13.7 1.0 C2D A:HEM417 4.3 13.1 1.0 C3C A:HEM417 4.3 14.3 1.0 C2A A:HEM417 4.3 11.4 1.0 C2B A:HEM417 4.3 12.6 1.0 C2C A:HEM417 4.3 13.4 1.0 C3B A:HEM417 4.3 11.8 1.0 C3A A:HEM417 4.3 12.2 1.0 N A:GLY359 4.6 11.9 1.0 C A:CYS357 4.7 12.9 1.0 N A:LEU358 4.8 13.4 1.0 CA A:GLY359 4.9 13.5 1.0

R.Raag, H.Li, B.C.Jones, T.L.Poulos. Inhibitor-Induced Conformational Change in Cytochrome P-450CAM. Biochemistry V. 32 4571 1993.
ISSN: ISSN 0006-2960
PubMed: 8485133
DOI: 10.1021/BI00068A013