Iron in PDB 1y4k: Lipoxygenase-1 (Soybean) at 100K, N694G Mutant

All present enzymatic activity of Lipoxygenase-1 (Soybean) at 100K, N694G Mutant:
1.13.11.12;

The structure of Lipoxygenase-1 (Soybean) at 100K, N694G Mutant, PDB code: 1y4k was solved by M.Chruszcz, E.Segraves, T.R.Holman, W.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.84 / 1.95
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	93.884, 92.835, 49.435, 90.00, 90.66, 90.00
R / Rfree (%)	18 / 23.2

The binding sites of Iron atom in the Lipoxygenase-1 (Soybean) at 100K, N694G Mutant (pdb code 1y4k). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Lipoxygenase-1 (Soybean) at 100K, N694G Mutant, PDB code: 1y4k:

Iron binding site 1 out of 1 in the Lipoxygenase-1 (Soybean) at 100K, N694G Mutant


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Lipoxygenase-1 (Soybean) at 100K, N694G Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe840 b:28.9 occ:0.70 O A:HOH1003 2.1 26.3 0.7 NE2 A:HIS504 2.2 24.4 1.0 OXT A:ILE839 2.2 29.0 1.0 O A:HOH1002 2.3 29.9 0.7 NE2 A:HIS690 2.3 20.1 1.0 NE2 A:HIS499 2.3 31.1 1.0 CE1 A:HIS499 3.0 32.0 1.0 CE1 A:HIS504 3.1 24.2 1.0 C A:ILE839 3.2 27.5 1.0 CD2 A:HIS690 3.2 21.6 1.0 CD2 A:HIS504 3.3 21.1 1.0 O A:ILE839 3.3 28.8 1.0 CE1 A:HIS690 3.4 23.5 1.0 CD2 A:HIS499 3.5 28.6 1.0 ND1 A:HIS499 4.2 30.4 1.0 ND1 A:HIS504 4.2 22.9 1.0 O A:HOH1001 4.3 22.3 0.7 CG A:HIS504 4.4 18.5 1.0 CG A:HIS690 4.4 19.7 1.0 CG A:HIS499 4.4 23.7 1.0 ND1 A:HIS690 4.4 18.2 1.0 CG2 A:ILE837 4.5 20.3 1.0 CA A:ILE839 4.6 25.4 1.0 N A:ILE839 4.9 23.1 1.0 OG1 A:THR503 5.0 17.4 1.0

E.N.Segraves, M.Chruszcz, M.L.Neidig, V.Ruddat, J.Zhou, A.T.Wecksler, W.Minor, E.I.Solomon, T.R.Holman. Kinetic, Spectroscopic, and Structural Investigations of the Soybean Lipoxygenase-1 First-Coordination Sphere Mutant, ASN694GLY. Biochemistry V. 45 10233 2006.
ISSN: ISSN 0006-2960
PubMed: 16922498
DOI: 10.1021/BI060577E