Atomistry » Iron » PDB 1yev-1yqo » 1yfx
Atomistry »
  Iron »
    PDB 1yev-1yqo »
      1yfx »

Iron in PDB 1yfx: Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No

Enzymatic activity of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No

All present enzymatic activity of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No:
1.13.11.6;

Protein crystallography data

The structure of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No, PDB code: 1yfx was solved by Y.Zhang, K.L.Colabroy, T.P.Begley, S.E.Ealick, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.95 / 2.00
Space group P 65 2 2
Cell size a, b, c (Å), α, β, γ (°) 57.900, 57.900, 230.600, 90.00, 90.00, 120.00
R / Rfree (%) 24.4 / 29.1

Other elements in 1yfx:

The structure of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No (pdb code 1yfx). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No, PDB code: 1yfx:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in 1yfx

Go back to Iron Binding Sites List in 1yfx
Iron binding site 1 out of 2 in the Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe300

b:41.8
occ:1.00
 OAD A:4AA401 2.1 40.0 1.0
N A:NO310 2.1 38.7 1.0
NE2 A:HIS95 2.1 37.4 1.0
OE1 A:GLU57 2.2 45.0 1.0
ND1 A:HIS51 2.2 42.8 1.0
OE2 A:GLU57 2.7 41.4 1.0
CD A:GLU57 2.8 41.9 1.0
CE1 A:HIS95 3.0 37.3 1.0
CAK A:4AA401 3.1 38.9 1.0
CE1 A:HIS51 3.1 40.9 1.0
CG A:HIS51 3.1 42.2 1.0
CD2 A:HIS95 3.2 34.6 1.0
O A:NO310 3.3 42.2 1.0
CB A:HIS51 3.5 39.2 1.0
NAA A:4AA401 3.5 37.2 1.0
CAI A:4AA401 3.7 40.9 1.0
OE2 A:GLU110 3.9 42.1 1.0
CAJ A:4AA401 4.1 38.2 1.0
ND1 A:HIS95 4.2 38.1 1.0
NE2 A:HIS51 4.2 45.7 1.0
CD2 A:HIS51 4.2 44.9 1.0
CG A:GLU57 4.3 39.9 1.0
CG A:HIS95 4.3 38.4 1.0
OD1 A:ASP53 4.4 39.8 1.0
CLAE A:4AA401 4.4 31.4 1.0
CB A:ASP53 4.5 41.2 1.0
CD A:GLU110 4.8 42.2 1.0
CA A:HIS51 4.9 41.4 1.0
CG A:ASP53 4.9 40.3 1.0
CAL A:4AA401 5.0 38.7 1.0

Iron binding site 2 out of 2 in 1yfx

Go back to Iron Binding Sites List in 1yfx
Iron binding site 2 out of 2 in the Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of 3-Hydroxyanthranilate-3,4-Dioxygenase From Ralstonia Metallidurans Complexed with 4-Chloro-3-Hydroxyanthranilic Acid and No within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe301

b:58.3
occ:1.00
 SG A:CYS128 2.3 63.8 1.0
SG A:CYS125 2.4 56.1 1.0
SG A:CYS162 2.4 58.7 1.0
SG A:CYS165 2.6 69.0 1.0
CB A:CYS125 2.9 56.2 1.0
CB A:CYS162 3.1 59.6 1.0
N A:CYS128 3.5 64.6 1.0
CB A:CYS128 3.5 64.2 1.0
CB A:CYS165 3.6 67.3 1.0
CA A:CYS128 4.0 64.1 1.0
N A:CYS165 4.0 67.9 1.0
CB A:ALA127 4.2 64.2 1.0
CB A:GLN167 4.4 63.1 1.0
CA A:CYS165 4.4 67.7 1.0
CA A:CYS125 4.4 56.5 1.0
C A:ALA127 4.5 65.1 1.0
CA A:CYS162 4.6 60.5 1.0
C A:CYS128 4.6 64.6 1.0
N A:GLY129 4.6 65.2 1.0
CB A:HIS130 4.7 65.5 1.0
CA A:ALA127 4.7 64.5 1.0
N A:GLN167 4.8 62.1 1.0
N A:HIS130 4.8 62.4 1.0
N A:ALA127 4.8 64.4 1.0
C A:CYS165 4.9 66.7 1.0
CB A:HIS164 4.9 70.8 1.0
C A:CYS125 4.9 57.6 1.0
N A:GLY166 5.0 65.3 1.0

Reference:

Y.Zhang, K.L.Colabroy, T.P.Begley, S.E.Ealick. Structural Studies on 3-Hydroxyanthranilate-3,4-Dioxygenase: the Catalytic Mechanism of A Complex Oxidation Involved in Nad Biosynthesis. Biochemistry V. 44 7632 2005.
ISSN: ISSN 0006-2960
PubMed: 15909978
DOI: 10.1021/BI047353L
Page generated: Wed Jul 16 22:41:12 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy