Iron in PDB 2g6n: Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co

All present enzymatic activity of Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co:
1.14.13.39;

The structure of Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co, PDB code: 2g6n was solved by H.Li, J.Igarashi, J.Jamal, W.Yang, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.55 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.970, 111.530, 164.370, 90.00, 90.00, 90.00
R / Rfree (%)	22.7 / 26.2

The structure of Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Iron atom in the Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co (pdb code 2g6n). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co, PDB code: 2g6n:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe750 b:24.1 occ:1.00 FE A:HEM750 0.0 24.1 1.0 C A:CMO920 1.7 32.0 1.0 NA A:HEM750 2.0 23.4 1.0 NC A:HEM750 2.0 21.9 1.0 NB A:HEM750 2.1 24.6 1.0 ND A:HEM750 2.1 24.3 1.0 SG A:CYS415 2.4 22.0 1.0 O A:CMO920 2.9 31.2 1.0 C1B A:HEM750 3.0 22.9 1.0 C4A A:HEM750 3.1 24.7 1.0 C1C A:HEM750 3.1 23.8 1.0 C4C A:HEM750 3.1 22.2 1.0 C4B A:HEM750 3.1 23.7 1.0 C1A A:HEM750 3.1 23.0 1.0 C1D A:HEM750 3.1 23.6 1.0 C4D A:HEM750 3.1 23.9 1.0 CHB A:HEM750 3.4 22.1 1.0 CB A:CYS415 3.4 22.2 1.0 CHC A:HEM750 3.4 23.4 1.0 CHD A:HEM750 3.4 23.1 1.0 CHA A:HEM750 3.5 22.5 1.0 CA A:CYS415 4.2 20.6 1.0 C3C A:HEM750 4.3 23.2 1.0 C2B A:HEM750 4.3 24.5 1.0 C3A A:HEM750 4.3 24.8 1.0 C2C A:HEM750 4.3 22.9 1.0 C3B A:HEM750 4.3 25.7 1.0 C2A A:HEM750 4.3 23.6 1.0 C2D A:HEM750 4.4 23.1 1.0 C3D A:HEM750 4.4 24.1 1.0 NE1 A:TRP409 4.4 24.6 1.0 NH1 A:ARG770 4.5 27.8 1.0 CZ A:ARG770 4.8 27.9 1.0 N A:GLY417 4.9 20.6 1.0 C A:CYS415 4.9 20.1 1.0 N A:VAL416 5.0 19.9 1.0

Iron binding site 2 out of 2 in the Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Strcture of Rat Nnos Heme Domain (BH2 Bound) Complexed with Co within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe750 b:23.5 occ:1.00 FE B:HEM750 0.0 23.5 1.0 C B:CMO920 1.7 32.2 1.0 NB B:HEM750 2.0 21.9 1.0 NC B:HEM750 2.0 20.9 1.0 NA B:HEM750 2.1 23.8 1.0 ND B:HEM750 2.1 23.1 1.0 SG B:CYS415 2.4 21.7 1.0 O B:CMO920 2.8 33.0 1.0 C4B B:HEM750 3.0 23.4 1.0 C1B B:HEM750 3.1 24.6 1.0 C4C B:HEM750 3.1 22.0 1.0 C1C B:HEM750 3.1 21.9 1.0 C1A B:HEM750 3.1 21.6 1.0 C1D B:HEM750 3.1 21.9 1.0 C4A B:HEM750 3.1 23.1 1.0 C4D B:HEM750 3.1 21.1 1.0 CB B:CYS415 3.3 19.6 1.0 CHC B:HEM750 3.4 18.4 1.0 CHD B:HEM750 3.4 21.9 1.0 CHB B:HEM750 3.5 23.2 1.0 CHA B:HEM750 3.5 20.8 1.0 CA B:CYS415 4.1 20.0 1.0 C2B B:HEM750 4.3 24.0 1.0 C3B B:HEM750 4.3 25.7 1.0 C2C B:HEM750 4.3 21.3 1.0 C2A B:HEM750 4.3 21.3 1.0 C3C B:HEM750 4.3 23.5 1.0 C3A B:HEM750 4.3 22.3 1.0 C2D B:HEM750 4.3 22.3 1.0 C3D B:HEM750 4.4 24.4 1.0 NE1 B:TRP409 4.5 21.6 1.0 NH1 B:ARG771 4.5 29.5 1.0 CZ B:ARG771 4.7 28.8 1.0 N B:GLY417 4.9 19.6 1.0 C B:CYS415 4.9 22.1 1.0 NH2 B:ARG771 4.9 24.8 1.0 N B:VAL416 5.0 20.1 1.0

H.Li, J.Igarashi, J.Jamal, W.Yang, T.L.Poulos. Structural Studies of Constitutive Nitric Oxide Synthases with Diatomic Ligands Bound. J.Biol.Inorg.Chem. V. 11 753 2006.
ISSN: ISSN 0949-8257
PubMed: 16804678
DOI: 10.1007/S00775-006-0123-8