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Atomistry » Iron » PDB 2vm0-2w3g » 2w0x | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 2vm0-2w3g » 2w0x » |
Iron in PDB 2w0x: Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic AcidEnzymatic activity of Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic Acid
All present enzymatic activity of Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic Acid:
1.14.11.16; Protein crystallography data
The structure of Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic Acid, PDB code: 2w0x
was solved by
A.Conejo-Garcia,
B.M.R.Lienard,
I.J.Clifton,
M.A.Mcdonough,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic Acid
(pdb code 2w0x). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic Acid, PDB code: 2w0x: Iron binding site 1 out of 1 in 2w0xGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Factor Inhibiting Hif-1 Alpha with Pyridine 2,4 Dicarboxylic Acid
![]() Mono view ![]() Stereo pair view
Reference:
A.Conejo-Garcia,
M.A.Mcdonough,
C.Loenarz,
L.A.Mcneill,
K.S.Hewitson,
W.Ge,
B.M.Lienard,
C.J.Schofield,
I.J.Clifton.
Structural Basis For Binding of Cyclic 2-Oxoglutarate Analogues to Factor-Inhibiting Hypoxia-Inducible Factor. Bioorg. Med. Chem. Lett. V. 20 6125 2010.
Page generated: Thu Jul 17 04:50:30 2025
ISSN: ESSN 1464-3405 PubMed: 20822901 DOI: 10.1016/J.BMCL.2010.08.032 |
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