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Atomistry » Iron » PDB 2xv1-2yde » 2y37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 2xv1-2yde » 2y37 » |
Iron in PDB 2y37: The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos)Enzymatic activity of The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos)
All present enzymatic activity of The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos):
1.14.13.39; Protein crystallography data
The structure of The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos), PDB code: 2y37
was solved by
D.R.Cheshire,
G.Andrews,
H.G.Beaton,
T.N.Birkinshaw,
N.Boughton-Smith,
S.Connolly,
T.R.Cook,
A.Cooper,
S.L.Cooper,
D.Cox,
J.Dixon,
N.Gensmantel,
P.J.Hamley,
R.Harrison,
P.Hartopp,
H.Kack,
T.Luker,
A.Mete,
I.Millichip,
D.J.Nicholls,
A.D.Pimm,
S.A.St-Gallay,
A.V.Wallace,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2y37:
The structure of The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos) also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos)
(pdb code 2y37). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos), PDB code: 2y37: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 2y37Go back to![]() ![]()
Iron binding site 1 out
of 2 in the The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos)
![]() Mono view ![]() Stereo pair view
Iron binding site 2 out of 2 in 2y37Go back to![]() ![]()
Iron binding site 2 out
of 2 in the The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos)
![]() Mono view ![]() Stereo pair view
Reference:
D.R.Cheshire,
A.Berg,
G.M.Andersson,
G.Andrews,
H.G.Beaton,
T.N.Birkinshaw,
N.Boughton-Smith,
S.Connolly,
T.R.Cook,
A.Cooper,
S.L.Cooper,
D.Cox,
J.Dixon,
N.Gensmantel,
P.J.Hamley,
R.Harrison,
P.Hartopp,
H.Kack,
P.D.Leeson,
T.Luker,
A.Mete,
I.Millichip,
D.J.Nicholls,
A.D.Pimm,
S.A.St-Gallay,
A.V.Wallace.
The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos). Bioorg.Med.Chem.Lett. V. 21 2468 2011.
Page generated: Thu Jul 17 05:51:09 2025
ISSN: ISSN 0960-894X PubMed: 21398123 DOI: 10.1016/J.BMCL.2011.02.061 |
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