Iron »
PDB 3jbt-3k9y »
3jt5 »
Iron in PDB 3jt5: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine
Enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine
All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine:
1.14.13.39;
1.14.13.39;
Protein crystallography data
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine, PDB code: 3jt5
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 35.72 / 2.10 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 52.020, 111.172, 164.374, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17.4 / 21 |
Other elements in 3jt5:
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine
(pdb code 3jt5). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine, PDB code: 3jt5:
Jump to Iron binding site number: 1; 2;
In total 2 binding sites of Iron where determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine, PDB code: 3jt5:
Jump to Iron binding site number: 1; 2;
Iron binding site 1 out of 2 in 3jt5
Go back to
Iron Binding Sites List in 3jt5
Iron binding site 1 out
of 2 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine within 5.0Å range:
|
Iron binding site 2 out of 2 in 3jt5
Go back to
Iron Binding Sites List in 3jt5
Iron binding site 2 out
of 2 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(Ethylsulfanyl)Ethanimidoyl]-L-Ornithine within 5.0Å range:
|
Reference:
J.D.Martell,
H.Li,
T.Doukov,
P.Martasek,
L.J.Roman,
M.Soltis,
T.L.Poulos,
R.B.Silverman.
Heme-Coordinating Inhibitors of Neuronal Nitric Oxide Synthase. Iron-Thioether Coordination Is Stabilized By Hydrophobic Contacts Without Increased Inhibitor Potency. J.Am.Chem.Soc. V. 132 798 2010.
ISSN: ISSN 0002-7863
PubMed: 20014790
DOI: 10.1021/JA908544F
Page generated: Sun Aug 4 13:35:10 2024
ISSN: ISSN 0002-7863
PubMed: 20014790
DOI: 10.1021/JA908544F
Last articles
F in 6FQJF in 6FZ4
F in 6FYZ
F in 6FW9
F in 6FWC
F in 6FW7
F in 6FS7
F in 6FVF
F in 6FS6
F in 6FTX
