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Atomistry » Iron » PDB 4cuo-4d36 » 4cx0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 4cuo-4d36 » 4cx0 » |
Iron in PDB 4cx0: Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-AmineEnzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
All present enzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine, PDB code: 4cx0
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4cx0:
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
(pdb code 4cx0). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine, PDB code: 4cx0: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 4cx0Go back to![]() ![]()
Iron binding site 1 out
of 2 in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Iron binding site 2 out of 2 in 4cx0Go back to![]() ![]()
Iron binding site 2 out
of 2 in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.Li,
J.Jamal,
S.L.Delker,
C.Plaza,
H.Ji,
Q.Jing,
H.Huang,
S.Kang,
R.B.Silverman,
T.L.Poulos.
Mobility of A Conserved Tyrosine Residue Controls Isoform- Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases. Biochemistry V. 53 5272 2014.
Page generated: Tue Aug 5 09:39:36 2025
ISSN: ISSN 0006-2960 PubMed: 25089924 DOI: 10.1021/BI500561H |
Last articlesI in 4J2VI in 4J1O I in 4J0R I in 4IWP I in 4IY9 I in 4ITJ I in 4IW0 I in 4ITH I in 4IUH I in 4IKM |
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