Iron in PDB 4g7l: Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2

All present enzymatic activity of Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2:
1.14.99.3;

The structure of Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2, PDB code: 4g7l was solved by M.Sugishima, K.Moffat, M.Noguchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.64 / 1.80
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	65.135, 65.135, 120.392, 90.00, 90.00, 120.00
R / Rfree (%)	15.6 / 18.3

The binding sites of Iron atom in the Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2 (pdb code 4g7l). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2, PDB code: 4g7l:

Iron binding site 1 out of 1 in the Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme and O2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe301 b:18.7 occ:1.00 FE A:HEM301 0.0 18.7 1.0 O1 A:OXY302 1.9 19.7 0.8 NC A:HEM301 1.9 17.7 1.0 NA A:HEM301 2.0 18.0 1.0 NB A:HEM301 2.0 18.8 1.0 ND A:HEM301 2.1 19.2 1.0 NE2 A:HIS25 2.1 19.6 1.0 O2 A:OXY302 2.7 28.5 0.8 C1D A:HEM301 3.0 17.8 1.0 C1B A:HEM301 3.0 19.6 1.0 C4C A:HEM301 3.0 17.5 1.0 C1C A:HEM301 3.0 18.0 1.0 CD2 A:HIS25 3.0 18.7 1.0 C4B A:HEM301 3.1 19.9 1.0 CE1 A:HIS25 3.1 19.2 1.0 C4D A:HEM301 3.1 18.7 1.0 C1A A:HEM301 3.1 19.6 1.0 C4A A:HEM301 3.1 20.0 1.0 CHD A:HEM301 3.3 17.3 1.0 CHB A:HEM301 3.4 19.4 1.0 CHC A:HEM301 3.4 18.8 1.0 CHA A:HEM301 3.5 18.1 1.0 CG A:HIS25 4.2 19.2 1.0 ND1 A:HIS25 4.2 20.9 1.0 C3C A:HEM301 4.3 18.8 1.0 C2D A:HEM301 4.3 17.4 1.0 N A:GLY143 4.3 19.3 1.0 C3D A:HEM301 4.3 18.1 1.0 C3B A:HEM301 4.3 19.9 1.0 C2B A:HEM301 4.3 21.0 1.0 C2C A:HEM301 4.4 19.1 1.0 C2A A:HEM301 4.4 21.5 1.0 C3A A:HEM301 4.4 20.3 1.0 CA A:GLY139 4.4 17.3 1.0 CA A:GLY143 4.6 20.8 1.0 O A:HOH485 4.6 33.6 1.0 CB A:SER142 4.7 18.0 1.0 O A:GLY139 4.9 19.0 1.0

M.Sugishima, K.Moffat, M.Noguchi. Discrimination Between Co and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes Following Co Photolysis Biochemistry 2012.
ISSN: ISSN 0006-2960
PubMed: 23043644
DOI: 10.1021/BI301175X