Atomistry » Iron » PDB 4oyn-4q1o » 4oyn
Atomistry »
  Iron »
    PDB 4oyn-4q1o »
      4oyn »

Iron in PDB 4oyn: Fifteen Minutes Iron Loaded Human H Ferritin

Enzymatic activity of Fifteen Minutes Iron Loaded Human H Ferritin

All present enzymatic activity of Fifteen Minutes Iron Loaded Human H Ferritin:
1.16.3.1;

Protein crystallography data

The structure of Fifteen Minutes Iron Loaded Human H Ferritin, PDB code: 4oyn was solved by C.Pozzi, F.Di Pisa, S.Mangani, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 31.09 / 1.43
Space group F 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 183.910, 183.910, 183.910, 90.00, 90.00, 90.00
R / Rfree (%) 16.7 / 17.9

Other elements in 4oyn:

The structure of Fifteen Minutes Iron Loaded Human H Ferritin also contains other interesting chemical elements:

Magnesium (Mg) 3 atoms
Chlorine (Cl) 13 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Fifteen Minutes Iron Loaded Human H Ferritin (pdb code 4oyn). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 7 binding sites of Iron where determined in the Fifteen Minutes Iron Loaded Human H Ferritin, PDB code: 4oyn:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7;

Iron binding site 1 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 1 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe203

b:9.5
occ:1.00
 OE2 A:GLU62 2.1 12.2 1.0
OE2 A:GLU27 2.1 9.3 1.0
O A:HOH601 2.1 12.3 1.0
O A:HOH611 2.1 20.4 1.0
ND1 A:HIS65 2.2 11.0 1.0
O A:HOH445 2.7 12.7 1.0
CE1 A:HIS65 3.0 11.4 1.0
CD A:GLU62 3.1 11.5 1.0
CD A:GLU27 3.1 9.0 1.0
CG A:HIS65 3.2 10.6 1.0
OE1 A:GLU27 3.4 9.3 1.0
OE1 A:GLU62 3.4 12.2 1.0
FE A:FE204 3.5 11.5 0.5
CB A:HIS65 3.6 9.9 1.0
NE2 A:GLN141 4.0 9.7 0.5
O A:HOH485 4.0 19.9 1.0
NE2 A:HIS65 4.2 11.6 1.0
NE2 A:GLN141 4.2 10.6 0.5
CG1 A:VAL110 4.3 12.9 1.0
CD2 A:HIS65 4.3 11.1 1.0
CG A:GLU62 4.4 10.8 1.0
CG A:GLU27 4.4 8.8 1.0
CA A:GLU62 4.5 9.9 1.0
CB A:GLU62 4.7 10.2 1.0
CB A:GLU27 4.8 8.4 1.0
CD A:GLN141 4.8 9.8 0.5
O A:HOH489 4.9 17.1 0.5
OE1 A:GLU107 5.0 14.2 1.0
OE1 A:GLN141 5.0 11.0 0.5

Iron binding site 2 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 2 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe204

b:11.5
occ:0.50
 O A:HOH611 1.9 20.4 1.0
OE1 A:GLU107 1.9 14.2 1.0
OE1 A:GLU62 1.9 12.2 1.0
O A:HOH489 2.2 17.1 0.5
OE2 A:GLU107 2.3 14.3 1.0
CD A:GLU107 2.4 13.5 1.0
O A:HOH445 2.5 12.7 1.0
CD A:GLU62 3.0 11.5 1.0
OE2 A:GLU62 3.4 12.2 1.0
NE2 A:GLN141 3.5 9.7 0.5
FE A:FE203 3.5 9.5 1.0
O A:HOH463 3.7 16.7 1.0
OE1 A:GLN141 3.8 9.9 0.5
CG A:GLU107 3.9 12.6 1.0
OE1 A:GLN141 4.0 11.0 0.5
CD A:GLN141 4.1 9.8 0.5
NE2 A:GLN141 4.1 10.6 0.5
O A:HOH467 4.2 16.4 1.0
O A:HOH617 4.3 23.5 1.0
CG A:GLU62 4.3 10.8 1.0
CD A:GLN141 4.3 10.6 0.5
CE1 A:HIS65 4.3 11.4 1.0
O A:HOH494 4.3 13.4 0.5
ND1 A:HIS65 4.5 11.0 1.0
O A:HOH601 4.6 12.3 1.0
CE2 A:TYR34 4.6 10.6 1.0
CB A:GLU107 4.7 11.7 1.0
OH A:TYR34 4.8 12.0 1.0
CA A:GLU107 4.9 11.2 1.0

Iron binding site 3 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 3 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe205

b:14.0
occ:0.50
 O A:HOH599 2.0 14.4 0.5
O A:HOH613 2.0 10.7 0.5
OE1 A:GLU61 2.1 12.8 0.7
O A:HOH605 2.1 11.6 0.5
OE1 A:GLN58 2.2 13.7 1.0
O A:HOH494 2.2 13.4 0.5
CD A:GLU61 3.0 12.0 0.7
CD A:GLN58 3.1 12.8 1.0
OE2 A:GLU61 3.3 12.5 0.7
NE2 A:GLN58 3.5 13.8 1.0
O A:HOH463 4.1 16.7 1.0
O A:HOH486 4.2 23.8 1.0
O A:HOH467 4.3 16.4 1.0
O A:HOH454 4.4 16.9 1.0
CG A:GLU61 4.4 11.5 1.0
O A:HOH491 4.4 19.4 1.0
O A:HOH482 4.4 18.5 1.0
O A:HOH617 4.5 23.5 1.0
O A:HOH489 4.5 17.1 0.5
CG A:GLN58 4.5 12.0 1.0
O A:HOH501 4.7 28.7 1.0
O A:HOH597 4.7 15.0 0.5
CB A:GLU61 4.8 10.6 1.0
CA A:GLN58 4.9 10.3 1.0

Iron binding site 4 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 4 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe206

b:14.0
occ:0.50
 O A:HOH612 2.1 17.9 0.5
OE2 A:GLU61 2.1 12.5 0.7
NE2 A:HIS57 2.1 13.4 0.8
O A:HOH606 2.1 16.7 0.5
O A:HOH603 2.1 16.0 0.5
O A:HOH597 2.2 15.0 0.5
CE1 A:HIS57 3.0 13.7 0.8
CD2 A:HIS57 3.1 13.2 0.8
CD A:GLU61 3.2 12.0 0.7
CG A:GLU61 3.7 11.5 1.0
O A:HOH613 4.1 10.7 0.5
ND1 A:HIS57 4.1 13.5 0.8
OE1 A:GLU61 4.2 12.8 0.7
CG A:HIS57 4.2 12.6 0.8

Iron binding site 5 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 5 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe207

b:7.5
occ:0.25
 O A:HOH386 2.1 11.7 0.2
NE2 A:HIS173 2.2 8.3 1.0
CL A:CL210 2.4 8.6 0.2
CE1 A:HIS173 3.1 8.4 1.0
CD2 A:HIS173 3.3 8.5 1.0
ND1 A:HIS173 4.2 8.6 1.0
CG A:HIS173 4.4 8.6 1.0
O A:HOH416 4.4 31.7 1.0

Iron binding site 6 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 6 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe208

b:11.4
occ:0.20
 O A:HOH405 2.1 11.6 1.0
O A:HOH319 2.1 11.5 1.0
OE2 A:GLU134 3.9 12.1 1.0
OE1 A:GLU134 4.2 12.7 1.0
O A:HOH425 4.3 12.6 1.0
O A:HOH451 4.3 13.7 1.0
CD A:GLU134 4.5 12.1 1.0

Iron binding site 7 out of 7 in 4oyn

Go back to Iron Binding Sites List in 4oyn
Iron binding site 7 out of 7 in the Fifteen Minutes Iron Loaded Human H Ferritin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Fifteen Minutes Iron Loaded Human H Ferritin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe209

b:20.6
occ:0.20
 O A:HOH324 1.7 11.4 0.5
O A:HOH315 2.0 16.1 0.5
OD2 A:ASP131 3.7 14.1 1.0
O A:HOH422 3.8 28.2 0.3
OG1 A:THR135 4.2 14.3 1.0
OE1 A:GLU134 4.3 12.7 1.0
O A:HOH335 4.6 18.6 0.7
CG A:ASP131 4.7 13.4 1.0

Reference:

C.Pozzi, F.Di Pisa, C.Bernacchioni, S.Ciambellotti, P.Turano, S.Mangani. Iron Binding to Human Heavy-Chain Ferritin. Acta Crystallogr.,Sect.D V. 71 1909 2015.
ISSN: ESSN 1399-0047
PubMed: 26327381
DOI: 10.1107/S1399004715013073
Page generated: Mon Aug 5 08:21:46 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy