Atomistry » Iron » PDB 5fp4-5g6e » 5g6b
Atomistry »
  Iron »
    PDB 5fp4-5g6e »
      5g6b »

Iron in PDB 5g6b: Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine

Enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine

All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine:
1.14.13.165;

Protein crystallography data

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine, PDB code: 5g6b was solved by J.K.Holden, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.60 / 1.80
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.640, 94.600, 61.960, 90.00, 90.00, 90.00
R / Rfree (%) 16.4 / 19.7

Other elements in 5g6b:

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine also contains other interesting chemical elements:

Fluorine (F) 2 atoms
Chlorine (Cl) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine (pdb code 5g6b). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine, PDB code: 5g6b:

Iron binding site 1 out of 1 in 5g6b

Go back to Iron Binding Sites List in 5g6b
Iron binding site 1 out of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with Two Molecules of 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe901

b:10.5
occ:1.00
 FE A:HEM901 0.0 10.5 1.0
ND A:HEM901 1.9 8.8 1.0
NA A:HEM901 2.0 9.3 1.0
NC A:HEM901 2.1 9.0 1.0
NB A:HEM901 2.1 11.6 1.0
SG A:CYS66 2.4 10.8 1.0
C1D A:HEM901 2.9 7.9 1.0
C4D A:HEM901 3.0 10.6 1.0
C1A A:HEM901 3.1 12.0 1.0
C4C A:HEM901 3.1 8.7 1.0
C4B A:HEM901 3.1 11.4 1.0
C4A A:HEM901 3.1 7.6 1.0
C1B A:HEM901 3.1 9.4 1.0
C1C A:HEM901 3.1 10.9 1.0
C04 A:M48904 3.3 10.3 1.0
CB A:CYS66 3.4 10.6 1.0
CHD A:HEM901 3.4 9.2 1.0
CHA A:HEM901 3.5 10.8 1.0
CHB A:HEM901 3.5 8.7 1.0
CHC A:HEM901 3.5 10.5 1.0
C03 A:M48904 3.6 11.3 1.0
C05 A:M48904 3.8 10.2 1.0
CA A:CYS66 4.1 9.3 1.0
C2D A:HEM901 4.2 10.4 1.0
C06 A:M48904 4.3 13.1 1.0
C3D A:HEM901 4.3 11.1 1.0
C2A A:HEM901 4.3 11.5 1.0
C3A A:HEM901 4.3 10.4 1.0
C02 A:M48904 4.3 10.9 1.0
C3C A:HEM901 4.3 9.9 1.0
C2C A:HEM901 4.3 11.9 1.0
C2B A:HEM901 4.3 10.0 1.0
C3B A:HEM901 4.4 10.5 1.0
NE1 A:TRP60 4.4 10.3 1.0
C10 A:M48904 4.4 11.5 1.0
N01 A:M48904 4.6 9.5 1.0
N A:GLY68 4.9 10.2 1.0
C A:CYS66 4.9 9.4 1.0

Reference:

J.K.Holden, M.C.Lewis, M.A.Cinelli, Z.Abdullatif, A.V.Pensa, R.B.Silverman, T.L.Poulos. Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry V. 55 5587 2016.
ISSN: ISSN 1520-4995
PubMed: 27607918
DOI: 10.1021/ACS.BIOCHEM.6B00786
Page generated: Tue Aug 5 21:38:59 2025

Last articles

Mo in 7W9D
Mo in 7UTA
Mo in 7UT9
Mo in 7UT8
Mo in 7UT7
Mo in 7UT6
Mo in 7PX0
Mo in 7T51
Mo in 7P41
Mo in 7MCI
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy