Iron in PDB 5jlc: Structure of CYP51 From the Pathogen Candida Glabrata

All present enzymatic activity of Structure of CYP51 From the Pathogen Candida Glabrata:
1.14.13.70;

The structure of Structure of CYP51 From the Pathogen Candida Glabrata, PDB code: 5jlc was solved by M.V.Keniya, M.Sabherwal, R.K.Wilson, A.A.Sagatova, J.D.A.Tyndall, B.C.Monk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.57 / 2.40
Space group	I 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	237.940, 237.940, 237.940, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 23.1

The structure of Structure of CYP51 From the Pathogen Candida Glabrata also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Iron atom in the Structure of CYP51 From the Pathogen Candida Glabrata (pdb code 5jlc). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of CYP51 From the Pathogen Candida Glabrata, PDB code: 5jlc:

Iron binding site 1 out of 1 in the Structure of CYP51 From the Pathogen Candida Glabrata


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of CYP51 From the Pathogen Candida Glabrata within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:35.3 occ:1.00 FE A:HEM601 0.0 35.3 1.0 N39 A:1YN602 2.0 62.9 1.0 NB A:HEM601 2.0 37.5 1.0 NC A:HEM601 2.0 39.8 1.0 ND A:HEM601 2.1 39.5 1.0 NA A:HEM601 2.1 35.9 1.0 SG A:CYS472 2.4 35.6 1.0 C40 A:1YN602 2.6 61.3 1.0 C4C A:HEM601 3.0 38.2 1.0 C4B A:HEM601 3.0 34.0 1.0 C1C A:HEM601 3.0 36.8 1.0 C1B A:HEM601 3.1 36.6 1.0 C1D A:HEM601 3.1 46.0 1.0 C4A A:HEM601 3.1 36.9 1.0 C4D A:HEM601 3.1 46.9 1.0 C1A A:HEM601 3.1 42.4 1.0 C38 A:1YN602 3.3 72.7 1.0 CB A:CYS472 3.4 34.6 1.0 CHD A:HEM601 3.4 45.3 1.0 CHC A:HEM601 3.4 33.8 1.0 CHB A:HEM601 3.5 37.2 1.0 CHA A:HEM601 3.5 43.6 1.0 N41 A:1YN602 3.9 77.8 1.0 N37 A:1YN602 4.2 76.2 1.0 CA A:CYS472 4.2 37.2 1.0 C3C A:HEM601 4.2 35.9 1.0 C2C A:HEM601 4.2 40.5 1.0 C3B A:HEM601 4.2 34.9 1.0 C2B A:HEM601 4.3 34.3 1.0 C2D A:HEM601 4.3 48.1 1.0 C3D A:HEM601 4.3 49.6 1.0 C3A A:HEM601 4.4 36.1 1.0 C2A A:HEM601 4.4 39.0 1.0 O A:GLY315 4.5 45.0 1.0 N A:GLY474 4.9 33.2 1.0 CD1 A:PHE465 5.0 34.8 1.0

M.V.Keniya, M.Sabherwal, R.K.Wilson, A.A.Sagatova, M.A.Woods, F.U.Huschmann, J.D.A.Tyndall, B.C.Monk. Structures of CYP51 From the Pathogens Candida Glabrata and Candida Albicans To Be Published.