Iron in PDB 5lg2: Horse L Type Ferritin Iron Loaded For 60 Minutes

The structure of Horse L Type Ferritin Iron Loaded For 60 Minutes, PDB code: 5lg2 was solved by C.Pozzi, F.Di Pisa, S.Mangani, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.61 / 2.22
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	181.350, 181.350, 181.350, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 22.4

The structure of Horse L Type Ferritin Iron Loaded For 60 Minutes also contains other interesting chemical elements:

Cadmium	(Cd)	3 atoms
Chlorine	(Cl)	1 atom

The binding sites of Iron atom in the Horse L Type Ferritin Iron Loaded For 60 Minutes (pdb code 5lg2). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Horse L Type Ferritin Iron Loaded For 60 Minutes, PDB code: 5lg2:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Horse L Type Ferritin Iron Loaded For 60 Minutes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Horse L Type Ferritin Iron Loaded For 60 Minutes within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe204 b:58.7 occ:1.00 O1 A:OXY209 2.0 29.7 1.0 OE2 A:GLU60 2.3 49.7 1.0 O2 A:PER211 2.3 42.5 1.0 OE2 A:GLU57 2.4 50.3 1.0 O2 A:PER210 2.5 59.9 1.0 OE1 A:GLU57 3.0 46.4 1.0 CD A:GLU57 3.0 49.7 1.0 O1 A:PER211 3.2 38.4 1.0 CD A:GLU60 3.4 47.0 1.0 O1 A:PER210 3.5 51.9 1.0 OE1 A:GLU60 3.7 51.6 1.0 FE A:FE206 3.8 82.4 1.0 FE A:FE205 4.0 80.6 1.0 O A:HOH336 4.2 54.4 1.0 CG A:GLU57 4.5 40.3 1.0 CG A:GLU60 4.7 40.2 1.0 OE2 A:GLU56 4.8 57.4 1.0 NH1 A:ARG64 4.9 69.8 1.0 CB A:GLU60 4.9 27.8 1.0

Iron binding site 2 out of 4 in the Horse L Type Ferritin Iron Loaded For 60 Minutes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Horse L Type Ferritin Iron Loaded For 60 Minutes within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe205 b:80.6 occ:1.00 O1 A:OXY209 2.2 29.7 1.0 OE2 A:GLU56 2.2 57.4 1.0 OE1 A:GLU60 2.4 51.6 1.0 O1 A:PER211 2.8 38.4 1.0 O A:HOH420 3.0 52.5 1.0 FE A:FE206 3.3 82.4 1.0 CD A:GLU56 3.4 51.6 1.0 CD A:GLU60 3.5 47.0 1.0 OE2 A:GLU60 3.8 49.7 1.0 O2 A:PER211 3.8 42.5 1.0 FE A:FE204 4.0 58.7 1.0 OE1 A:GLU56 4.0 62.6 1.0 CG A:GLU56 4.6 40.5 1.0 O1 A:PER210 4.7 51.9 1.0 CG A:GLU60 4.8 40.2 1.0 O2 A:PER210 4.9 59.9 1.0

Iron binding site 3 out of 4 in the Horse L Type Ferritin Iron Loaded For 60 Minutes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Horse L Type Ferritin Iron Loaded For 60 Minutes within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe206 b:82.4 occ:1.00 O1 A:OXY209 2.3 29.7 1.0 OE1 A:GLU53 2.3 64.6 1.0 O1 A:PER210 2.9 51.9 1.0 OE1 A:GLU57 3.0 46.4 1.0 OE1 A:GLU56 3.0 62.6 1.0 OE2 A:GLU56 3.0 57.4 1.0 CD A:GLU53 3.2 60.3 1.0 CD A:GLU56 3.2 51.6 1.0 OE2 A:GLU53 3.3 62.5 1.0 FE A:FE205 3.3 80.6 1.0 O A:HOH420 3.5 52.5 1.0 O2 A:PER210 3.7 59.9 1.0 FE A:FE204 3.8 58.7 1.0 CD A:GLU57 4.2 49.7 1.0 OE1 A:GLU60 4.3 51.6 1.0 FE A:FE207 4.4 48.2 0.4 CG A:GLU56 4.5 40.5 1.0 CG A:GLU53 4.6 47.3 1.0 OE2 A:GLU60 4.7 49.7 1.0 OE2 A:GLU57 4.8 50.3 1.0 O A:GLU53 4.8 23.0 1.0 CD A:GLU60 4.8 47.0 1.0 CB A:GLU56 4.9 26.7 1.0 O1 A:PER211 5.0 38.4 1.0

Iron binding site 4 out of 4 in the Horse L Type Ferritin Iron Loaded For 60 Minutes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Horse L Type Ferritin Iron Loaded For 60 Minutes within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe207 b:48.2 occ:0.40 OE1 A:GLU56 2.7 62.6 1.0 OE2 A:GLU53 2.9 62.5 1.0 O A:HOH420 3.4 52.5 1.0 CD A:GLU56 3.9 51.6 1.0 CD A:GLU53 4.1 60.3 1.0 FE A:FE206 4.4 82.4 1.0 OE2 A:GLU56 4.5 57.4 1.0 OE1 A:GLU53 4.7 64.6 1.0 CG A:GLU56 4.9 40.5 1.0

C.Pozzi, S.Ciambellotti, C.Bernacchioni, F.Di Pisa, S.Mangani, P.Turano. Chemistry at the Protein-Mineral Interface in L-Ferritin Assists the Assembly of A Functional ( Mu (3)-Oxo)Tris[( Mu (2)-Peroxo)] Triiron(III) Cluster. Proc. Natl. Acad. Sci. V. 114 2580 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 28202724
DOI: 10.1073/PNAS.1614302114