Iron »
PDB 5tis-5ufj »
5tpg »
Iron in PDB 5tpg: Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors
Enzymatic activity of Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors
All present enzymatic activity of Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors:
1.14.16.4;
1.14.16.4;
Protein crystallography data
The structure of Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors, PDB code: 5tpg
was solved by
A.J.Stein,
D.R.Goldberg,
S.De Lombaert,
M.C.Holt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 33.67 / 1.50 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 47.198, 58.161, 51.567, 90.00, 93.72, 90.00 |
| R / Rfree (%) | 18.7 / 21.5 |
Other elements in 5tpg:
The structure of Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors also contains other interesting chemical elements:
| Fluorine | (F) | 3 atoms |
| Chlorine | (Cl) | 1 atom |
Iron Binding Sites:
The binding sites of Iron atom in the Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors
(pdb code 5tpg). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors, PDB code: 5tpg:
In total only one binding site of Iron was determined in the Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors, PDB code: 5tpg:
Iron binding site 1 out of 1 in 5tpg
Go back to
Iron Binding Sites List in 5tpg
Iron binding site 1 out
of 1 in the Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors within 5.0Å range:
|
Reference:
D.R.Goldberg,
S.De Lombaert,
R.Aiello,
P.Bourassa,
N.Barucci,
Q.Zhang,
V.Paralkar,
A.J.Stein,
M.Holt,
J.Valentine,
W.Zavadoski.
Optimization of Spirocyclic Proline Tryptophan Hydroxylase-1 Inhibitors. Bioorg. Med. Chem. Lett. V. 27 413 2017.
ISSN: ESSN 1464-3405
PubMed: 28041831
DOI: 10.1016/J.BMCL.2016.12.053
Page generated: Tue Aug 6 09:41:13 2024
ISSN: ESSN 1464-3405
PubMed: 28041831
DOI: 10.1016/J.BMCL.2016.12.053
Last articles
Zn in 9MJ5Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
