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Atomistry » Iron » PDB 5vux-5whs » 5w58 » |
Iron in PDB 5w58: Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor)Enzymatic activity of Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor)
All present enzymatic activity of Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor):
1.14.99.1; Protein crystallography data
The structure of Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor), PDB code: 5w58
was solved by
S.Xu,
M.C.Goodman,
S.Banerjee,
D.Piomelli,
L.J.Marnett,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5w58:
The structure of Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor) also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor)
(pdb code 5w58). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor), PDB code: 5w58: Iron binding site 1 out of 1 in 5w58Go back to![]() ![]()
Iron binding site 1 out
of 1 in the Crystal Complex of Cyclooxygenase-2: (S)-Arn-2508 (A Dual Cox and Faah Inhibitor)
![]() Mono view ![]() Stereo pair view
Reference:
M.C.Goodman,
S.Xu,
C.A.Rouzer,
S.Banerjee,
K.Ghebreselasie,
M.Migliore,
D.Piomelli,
L.J.Marnett.
Dual Cyclooxygenase-Fatty Acid Amide Hydrolase Inhibitor Exploits Novel Binding Interactions in the Cyclooxygenase Active Site. J. Biol. Chem. V. 293 3028 2018.
Page generated: Tue Aug 6 11:05:54 2024
ISSN: ESSN 1083-351X PubMed: 29326169 DOI: 10.1074/JBC.M117.802058 |
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