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PDB 6htk-6i93 »
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Iron in PDB 6i8a: The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution.
Enzymatic activity of The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution.
All present enzymatic activity of The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution.:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution., PDB code: 6i8a
was solved by
V.Parkash,
E.Johansson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 19.96 / 2.65 |
| Space group | P 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 154.466, 70.257, 159.335, 90.00, 112.85, 90.00 |
| R / Rfree (%) | 22.9 / 27.9 |
Other elements in 6i8a:
The structure of The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution. also contains other interesting chemical elements:
| Calcium | (Ca) | 4 atoms |
Iron Binding Sites:
The binding sites of Iron atom in the The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution.
(pdb code 6i8a). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution., PDB code: 6i8a:
Jump to Iron binding site number: 1; 2;
In total 2 binding sites of Iron where determined in the The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution., PDB code: 6i8a:
Jump to Iron binding site number: 1; 2;
Iron binding site 1 out of 2 in 6i8a
Go back to
Iron Binding Sites List in 6i8a
Iron binding site 1 out
of 2 in the The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution. within 5.0Å range:
|
Iron binding site 2 out of 2 in 6i8a
Go back to
Iron Binding Sites List in 6i8a
Iron binding site 2 out
of 2 in the The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 2 of The Crystal Structure of the POL2 Catalytic Domain of Dna Polymerase Epsilon Carrying A P301R Substitution. within 5.0Å range:
|
Reference:
V.Parkash,
Y.Kulkarni,
J.Ter Beek,
P.V.Shcherbakova,
S.C.L.Kamerlin,
E.Johansson.
Structural Consequence of the Most Frequently Recurring Cancer-Associated Substitution in Dna Polymerase Epsilon. Nat Commun V. 10 373 2019.
ISSN: ESSN 2041-1723
PubMed: 30670696
DOI: 10.1038/S41467-018-08114-9
Page generated: Tue Aug 6 22:13:55 2024
ISSN: ESSN 2041-1723
PubMed: 30670696
DOI: 10.1038/S41467-018-08114-9
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