Iron in PDB 6ro4: Structure of the Core Tfiih-Xpa-Dna Complex

All present enzymatic activity of Structure of the Core Tfiih-Xpa-Dna Complex:
3.6.4.12;

The structure of Structure of the Core Tfiih-Xpa-Dna Complex also contains other interesting chemical elements:

Zinc

(Zn)

6 atoms

The binding sites of Iron atom in the Structure of the Core Tfiih-Xpa-Dna Complex (pdb code 6ro4). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Structure of the Core Tfiih-Xpa-Dna Complex, PDB code: 6ro4:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Structure of the Core Tfiih-Xpa-Dna Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of the Core Tfiih-Xpa-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:87.9 occ:1.00 FE1 B:SF41000 0.0 87.9 1.0 S2 B:SF41000 2.3 87.9 1.0 S4 B:SF41000 2.3 87.9 1.0 S3 B:SF41000 2.3 87.9 1.0 FE3 B:SF41000 2.7 87.9 1.0 FE2 B:SF41000 2.7 87.9 1.0 FE4 B:SF41000 2.7 87.9 1.0 SG B:CYS116 3.1 82.1 1.0 CA B:CYS116 3.7 82.1 1.0 S1 B:SF41000 3.9 87.9 1.0 CB B:CYS116 3.9 82.1 1.0 N B:ILE117 4.0 85.7 1.0 O B:LEU115 4.2 72.0 1.0 C B:CYS116 4.4 82.1 1.0 N B:HIS118 4.4 90.6 1.0 CB B:HIS118 4.5 90.6 1.0 CG1 B:VAL121 4.6 0.1 1.0 N B:CYS116 4.8 82.1 1.0 C B:LEU115 4.9 72.0 1.0

Iron binding site 2 out of 4 in the Structure of the Core Tfiih-Xpa-Dna Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of the Core Tfiih-Xpa-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:87.9 occ:1.00 FE2 B:SF41000 0.0 87.9 1.0 S4 B:SF41000 2.3 87.9 1.0 S1 B:SF41000 2.3 87.9 1.0 S3 B:SF41000 2.3 87.9 1.0 FE3 B:SF41000 2.7 87.9 1.0 FE1 B:SF41000 2.7 87.9 1.0 FE4 B:SF41000 2.7 87.9 1.0 SG B:CYS155 3.1 87.7 1.0 S2 B:SF41000 3.9 87.9 1.0 CB B:CYS155 4.0 87.7 1.0 CB B:HIS118 4.3 90.6 1.0 SG B:CYS134 4.5 88.4 1.0 CG2 B:THR138 4.8 98.4 1.0 CG B:HIS118 4.9 90.6 1.0 CG1 B:VAL121 4.9 0.1 1.0

Iron binding site 3 out of 4 in the Structure of the Core Tfiih-Xpa-Dna Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Structure of the Core Tfiih-Xpa-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:87.9 occ:1.00 FE3 B:SF41000 0.0 87.9 1.0 S2 B:SF41000 2.3 87.9 1.0 S1 B:SF41000 2.3 87.9 1.0 S4 B:SF41000 2.3 87.9 1.0 FE2 B:SF41000 2.7 87.9 1.0 FE4 B:SF41000 2.7 87.9 1.0 FE1 B:SF41000 2.7 87.9 1.0 SG B:CYS134 3.1 88.4 1.0 S3 B:SF41000 3.9 87.9 1.0 CB B:CYS134 4.1 88.4 1.0 CG B:ARG112 4.6 78.2 1.0 SG B:CYS190 4.7 80.3 1.0 NE B:ARG112 4.8 78.2 1.0 CD B:ARG112 4.8 78.2 1.0 CE2 B:PHE193 4.9 73.5 1.0

Iron binding site 4 out of 4 in the Structure of the Core Tfiih-Xpa-Dna Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Structure of the Core Tfiih-Xpa-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:87.9 occ:1.00 FE4 B:SF41000 0.0 87.9 1.0 S1 B:SF41000 2.3 87.9 1.0 S3 B:SF41000 2.3 87.9 1.0 S2 B:SF41000 2.3 87.9 1.0 FE3 B:SF41000 2.7 87.9 1.0 FE2 B:SF41000 2.7 87.9 1.0 FE1 B:SF41000 2.7 87.9 1.0 SG B:CYS190 3.1 80.3 1.0 CB B:CYS190 3.4 80.3 1.0 S4 B:SF41000 3.9 87.9 1.0 CA B:CYS190 4.1 80.3 1.0 SG B:CYS155 4.2 87.7 1.0 CD B:PRO191 4.6 71.6 1.0 CB B:PHE157 4.7 91.4 1.0

G.Kokic, A.Chernev, D.Tegunov, C.Dienemann, H.Urlaub, P.Cramer. Structural Basis of Tfiih Activation For Nucleotide Excision Repair. Nat Commun V. 10 2885 2019.
ISSN: ESSN 2041-1723
PubMed: 31253769
DOI: 10.1038/S41467-019-10745-5