Iron in PDB 6tnz: Human Polymerase Delta-FEN1-Pcna Toolbelt

All present enzymatic activity of Human Polymerase Delta-FEN1-Pcna Toolbelt:
2.7.7.7;

The structure of Human Polymerase Delta-FEN1-Pcna Toolbelt also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Iron atom in the Human Polymerase Delta-FEN1-Pcna Toolbelt (pdb code 6tnz). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Human Polymerase Delta-FEN1-Pcna Toolbelt, PDB code: 6tnz:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Human Polymerase Delta-FEN1-Pcna Toolbelt


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Polymerase Delta-FEN1-Pcna Toolbelt within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1202 b:40.6 occ:1.00 FE1 A:SF41202 0.0 40.6 1.0 SG A:CYS1071 2.3 40.6 1.0 S3 A:SF41202 2.3 40.6 1.0 S2 A:SF41202 2.3 40.6 1.0 S4 A:SF41202 2.3 40.6 1.0 FE4 A:SF41202 2.7 40.6 1.0 FE3 A:SF41202 2.7 40.6 1.0 FE2 A:SF41202 2.7 40.6 1.0 CB A:CYS1071 3.3 40.6 1.0 O A:CYS1071 3.8 40.6 1.0 S1 A:SF41202 3.9 40.6 1.0 CG2 A:ILE1078 4.0 40.6 1.0 C A:CYS1071 4.4 40.6 1.0 SG A:CYS1076 4.4 30.9 1.0 CA A:CYS1071 4.4 40.6 1.0 CB A:SER1073 4.5 35.8 1.0 CB A:CYS1076 4.6 30.9 1.0 SG A:CYS1058 4.6 40.6 1.0 SG A:CYS1061 4.8 24.8 1.0 NH1 A:ARG1082 4.9 40.6 1.0 CB A:ILE1078 4.9 40.6 1.0 N A:SER1073 4.9 35.8 1.0

Iron binding site 2 out of 4 in the Human Polymerase Delta-FEN1-Pcna Toolbelt


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Polymerase Delta-FEN1-Pcna Toolbelt within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1202 b:40.6 occ:1.00 FE2 A:SF41202 0.0 40.6 1.0 CG2 A:ILE1078 2.3 40.6 1.0 SG A:CYS1076 2.3 30.9 1.0 S4 A:SF41202 2.3 40.6 1.0 S1 A:SF41202 2.3 40.6 1.0 S3 A:SF41202 2.3 40.6 1.0 CB A:ILE1078 2.4 40.6 1.0 FE3 A:SF41202 2.7 40.6 1.0 FE1 A:SF41202 2.7 40.6 1.0 FE4 A:SF41202 2.8 40.6 1.0 CG1 A:ILE1078 3.3 40.6 1.0 CB A:CYS1076 3.3 30.9 1.0 CA A:ILE1078 3.6 40.6 1.0 N A:PHE1079 3.9 40.6 1.0 S2 A:SF41202 3.9 40.6 1.0 N A:ILE1078 4.0 40.6 1.0 C A:ILE1078 4.0 40.6 1.0 CD1 A:ILE1078 4.6 40.6 1.0 CA A:CYS1076 4.7 30.9 1.0 SG A:CYS1058 4.8 40.6 1.0 SG A:CYS1071 4.9 40.6 1.0 C A:CYS1076 4.9 30.9 1.0 CA A:PHE1079 5.0 40.6 1.0

Iron binding site 3 out of 4 in the Human Polymerase Delta-FEN1-Pcna Toolbelt


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Polymerase Delta-FEN1-Pcna Toolbelt within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1202 b:40.6 occ:1.00 FE3 A:SF41202 0.0 40.6 1.0 S1 A:SF41202 2.3 40.6 1.0 SG A:CYS1058 2.3 40.6 1.0 S4 A:SF41202 2.3 40.6 1.0 S2 A:SF41202 2.3 40.6 1.0 CG2 A:ILE1078 2.3 40.6 1.0 FE2 A:SF41202 2.7 40.6 1.0 FE4 A:SF41202 2.7 40.6 1.0 FE1 A:SF41202 2.7 40.6 1.0 CB A:CYS1058 3.5 40.6 1.0 CA A:CYS1058 3.7 40.6 1.0 CB A:ILE1078 3.7 40.6 1.0 S3 A:SF41202 3.8 40.6 1.0 N A:CYS1058 4.4 40.6 1.0 CG1 A:ILE1078 4.5 40.6 1.0 NE A:ARG1082 4.5 40.6 1.0 SG A:CYS1061 4.8 24.8 1.0 SG A:CYS1071 4.8 40.6 1.0 C A:CYS1058 4.9 40.6 1.0 SG A:CYS1076 4.9 30.9 1.0 NH1 A:ARG1082 5.0 40.6 1.0 CB A:CYS1061 5.0 24.8 1.0 CA A:ILE1078 5.0 40.6 1.0

Iron binding site 4 out of 4 in the Human Polymerase Delta-FEN1-Pcna Toolbelt


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Polymerase Delta-FEN1-Pcna Toolbelt within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1202 b:40.6 occ:1.00 FE4 A:SF41202 0.0 40.6 1.0 S2 A:SF41202 2.3 40.6 1.0 S3 A:SF41202 2.3 40.6 1.0 S1 A:SF41202 2.3 40.6 1.0 SG A:CYS1061 2.4 24.8 1.0 FE1 A:SF41202 2.7 40.6 1.0 FE3 A:SF41202 2.7 40.6 1.0 FE2 A:SF41202 2.8 40.6 1.0 CB A:CYS1061 3.4 24.8 1.0 S4 A:SF41202 3.9 40.6 1.0 SG A:CYS1076 4.1 30.9 1.0 CG2 A:ILE1078 4.1 40.6 1.0 SG A:CYS1071 4.4 40.6 1.0 CB A:ILE1078 4.7 40.6 1.0 CA A:CYS1061 4.8 24.8 1.0 SG A:CYS1058 4.8 40.6 1.0 CA A:CYS1058 5.0 40.6 1.0

C.Lancey, M.Tehseen, V.S.Raducanu, F.Rashid, N.Merino, T.J.Ragan, C.Savva, M.S.Zaher, A.Shirbini, F.J.Blanco, S.M.Hamdan, A.De Biasio. Structure of the Processive Human Pol Delta Holoenzyme To Be Published.