Iron in PDB 6zkt: Deactive Complex I, OPEN2

All present enzymatic activity of Deactive Complex I, OPEN2:
7.1.1.2;

The structure of Deactive Complex I, OPEN2 also contains other interesting chemical elements:

Potassium	(K)	1 atom
Zinc	(Zn)	1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Deactive Complex I, OPEN2 (pdb code 6zkt). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Deactive Complex I, OPEN2, PDB code: 6zkt:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 1:Fe500 b:58.1 occ:1.00 FE1 1:SF4500 0.0 58.1 1.0 S2 1:SF4500 2.3 45.8 1.0 S3 1:SF4500 2.3 46.0 1.0 S4 1:SF4500 2.3 69.1 1.0 SG 1:CYS365 2.3 37.5 1.0 FE3 1:SF4500 2.8 29.7 1.0 FE2 1:SF4500 2.8 39.9 1.0 CB 1:CYS365 2.8 19.2 1.0 FE4 1:SF4500 2.9 34.5 1.0 OG 1:SER358 3.0 23.3 1.0 CD2 1:LEU407 4.1 36.1 1.0 S1 1:SF4500 4.2 46.9 1.0 CB 1:SER358 4.2 27.1 1.0 CA 1:CYS365 4.2 23.5 1.0 CB 1:LEU407 4.4 26.4 1.0 C 1:CYS365 4.5 26.1 1.0 N 1:CYS359 4.5 28.5 1.0 CA 1:SER358 4.6 30.4 1.0 N 1:ARG366 4.6 24.9 1.0 CG 1:LEU407 4.8 33.2 1.0 N 1:GLY360 4.8 23.6 1.0 N 1:GLY408 4.9 37.2 1.0 C 1:SER358 4.9 35.4 1.0 N 1:CYS365 5.0 22.3 1.0

Iron binding site 2 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 1:Fe500 b:39.9 occ:1.00 FE2 1:SF4500 0.0 39.9 1.0 S3 1:SF4500 2.3 46.0 1.0 S1 1:SF4500 2.3 46.9 1.0 S4 1:SF4500 2.4 69.1 1.0 FE3 1:SF4500 2.5 29.7 1.0 FE4 1:SF4500 2.6 34.5 1.0 FE1 1:SF4500 2.8 58.1 1.0 SG 1:CYS362 3.0 35.2 1.0 N 1:CYS362 3.8 14.6 1.0 S2 1:SF4500 3.8 45.8 1.0 CB 1:CYS362 4.1 16.2 1.0 CB 1:CYS365 4.1 19.2 1.0 N 1:ILE404 4.3 29.1 1.0 O 1:CYS362 4.4 18.5 1.0 CA 1:CYS362 4.4 16.5 1.0 CB 1:THR403 4.4 23.2 1.0 CB 1:ILE404 4.5 29.5 1.0 CB 1:GLN361 4.6 21.0 1.0 N 1:GLN361 4.6 23.2 1.0 SG 1:CYS365 4.6 37.5 1.0 C 1:CYS362 4.8 16.3 1.0 N 1:CYS405 4.8 27.4 1.0 C 1:GLN361 4.8 23.6 1.0 CA 1:GLN361 4.9 43.3 1.0 CG1 1:ILE404 4.9 22.2 1.0 CA 1:ILE404 5.0 27.4 1.0 CG2 1:THR403 5.0 28.9 1.0

Iron binding site 3 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 1:Fe500 b:29.7 occ:1.00 FE3 1:SF4500 0.0 29.7 1.0 S4 1:SF4500 2.3 69.1 1.0 S1 1:SF4500 2.3 46.9 1.0 S2 1:SF4500 2.4 45.8 1.0 FE4 1:SF4500 2.5 34.5 1.0 FE2 1:SF4500 2.5 39.9 1.0 FE1 1:SF4500 2.8 58.1 1.0 SG 1:CYS359 2.9 38.0 1.0 N 1:GLN361 3.5 23.2 1.0 N 1:GLY360 3.6 23.6 1.0 N 1:CYS359 3.6 28.5 1.0 S3 1:SF4500 3.7 46.0 1.0 CB 1:GLN361 3.9 21.0 1.0 CB 1:CYS359 3.9 35.0 1.0 CA 1:CYS359 4.0 28.4 1.0 C 1:CYS359 4.1 22.4 1.0 OG 1:SER358 4.3 23.3 1.0 CA 1:GLN361 4.3 43.3 1.0 C 1:GLY360 4.4 23.3 1.0 CA 1:GLY360 4.5 18.2 1.0 N 1:CYS362 4.5 14.6 1.0 C 1:SER358 4.6 35.4 1.0 CD 1:PRO203 4.6 24.3 1.0 OE1 1:GLN361 4.9 17.6 1.0 SG 1:CYS365 4.9 37.5 1.0 C 1:GLN361 5.0 23.6 1.0 O 1:CYS359 5.0 31.5 1.0 CD1 1:ILE185 5.0 28.2 1.0 CG1 1:ILE185 5.0 25.6 1.0

Iron binding site 4 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 1:Fe500 b:34.5 occ:1.00 FE4 1:SF4500 0.0 34.5 1.0 S2 1:SF4500 2.3 45.8 1.0 S1 1:SF4500 2.3 46.9 1.0 S3 1:SF4500 2.4 46.0 1.0 FE3 1:SF4500 2.5 29.7 1.0 FE2 1:SF4500 2.6 39.9 1.0 FE1 1:SF4500 2.9 58.1 1.0 SG 1:CYS405 3.0 32.5 1.0 S4 1:SF4500 3.9 69.1 1.0 CD1 1:ILE185 3.9 28.2 1.0 CG 1:PRO203 4.1 27.1 1.0 CB 1:LEU407 4.2 26.4 1.0 CB 1:CYS405 4.3 35.7 1.0 N 1:CYS405 4.3 27.4 1.0 CD 1:PRO203 4.4 24.3 1.0 SG 1:CYS359 4.6 38.0 1.0 CG1 1:ILE185 4.6 25.6 1.0 CA 1:CYS405 4.7 25.4 1.0 O 1:CYS405 4.8 34.1 1.0 C 1:CYS405 4.8 27.1 1.0 N 1:LEU407 4.9 26.9 1.0 SG 1:CYS365 5.0 37.5 1.0

Iron binding site 5 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 2:Fe300 b:0.7 occ:1.00 FE1 2:FES300 0.0 0.7 1.0 S2 2:FES300 2.2 50.5 1.0 S1 2:FES300 2.2 53.6 1.0 SG 2:CYS103 2.3 45.2 1.0 SG 2:CYS108 2.3 60.1 1.0 FE2 2:FES300 3.0 48.5 1.0 CB 2:CYS103 3.2 36.8 1.0 CB 2:CYS108 3.3 47.8 1.0 OG1 2:THR105 3.6 52.5 1.0 N 2:CYS108 4.1 40.5 1.0 CA 2:CYS108 4.3 41.9 1.0 N 2:LEU145 4.4 38.0 1.0 CA 2:CYS144 4.4 33.2 1.0 CA 2:CYS103 4.5 38.2 1.0 C 2:CYS103 4.6 38.2 1.0 SD 2:MET153 4.7 62.0 1.0 SG 2:CYS144 4.7 75.5 1.0 O 2:CYS103 4.8 40.7 1.0 N 2:THR105 4.8 36.6 1.0 CB 2:CYS144 4.9 40.8 1.0 CB 2:THR105 4.9 37.1 1.0 C 2:CYS144 4.9 43.6 1.0 SG 2:CYS148 4.9 44.2 1.0 CG 2:MET153 5.0 57.6 1.0

Iron binding site 6 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 2:Fe300 b:48.5 occ:1.00 FE2 2:FES300 0.0 48.5 1.0 S2 2:FES300 2.2 50.5 1.0 S1 2:FES300 2.2 53.6 1.0 SG 2:CYS148 2.3 44.2 1.0 SG 2:CYS144 2.3 75.5 1.0 FE1 2:FES300 3.0 0.7 1.0 CB 2:CYS144 3.5 40.8 1.0 CB 2:CYS148 3.6 45.8 1.0 N 2:GLY146 3.8 36.1 1.0 CA 2:CYS144 3.9 33.2 1.0 CA 2:CYS148 3.9 44.9 1.0 N 2:LEU145 4.0 38.0 1.0 OG1 2:THR105 4.2 52.5 1.0 N 2:CYS148 4.2 47.3 1.0 C 2:CYS144 4.2 43.6 1.0 N 2:ALA147 4.2 43.0 1.0 N 1:GLY103 4.3 36.0 1.0 CA 2:GLY146 4.3 34.1 1.0 SG 2:CYS103 4.5 45.2 1.0 CA 1:PRO102 4.6 38.0 1.0 C 2:ALA147 4.7 48.3 1.0 C 2:GLY146 4.7 40.7 1.0 C 2:LEU145 4.8 37.6 1.0 CB 2:PRO107 4.9 34.7 1.0 CG 2:PRO107 4.9 37.3 1.0 SG 2:CYS108 4.9 60.1 1.0 O 1:GLU101 5.0 49.4 1.0 CA 2:LEU145 5.0 33.1 1.0

Iron binding site 7 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 3:Fe801 b:77.9 occ:1.00 FE1 3:SF4801 0.0 77.9 1.0 S2 3:SF4801 2.3 77.9 1.0 S3 3:SF4801 2.3 77.9 1.0 S4 3:SF4801 2.3 77.9 1.0 SG 3:CYS114 2.3 27.6 1.0 FE3 3:SF4801 2.7 77.9 1.0 FE4 3:SF4801 2.7 77.9 1.0 FE2 3:SF4801 2.7 77.9 1.0 CB 3:CYS114 3.4 22.6 1.0 S1 3:SF4801 3.9 77.9 1.0 CG 3:GLN117 4.2 20.3 1.0 NE2 3:HIS101 4.2 49.1 1.0 CG 3:GLN110 4.4 21.1 1.0 CB 3:LEU116 4.4 17.1 1.0 CB 3:GLN110 4.5 16.6 1.0 N 3:GLN117 4.6 58.5 1.0 CD 3:GLN117 4.6 20.2 1.0 N 3:GLY206 4.7 19.4 1.0 SG 3:CYS108 4.7 17.0 1.0 CA 3:CYS114 4.7 25.0 1.0 NE2 3:GLN117 4.7 20.2 1.0 CA 3:VAL205 4.8 16.8 1.0 SG 3:CYS105 4.8 31.4 1.0 CD2 3:LEU116 4.8 20.2 1.0 CB 3:VAL205 4.9 27.6 1.0 CE1 3:HIS101 4.9 61.7 1.0 CB 3:GLN117 5.0 31.0 1.0 CG1 3:VAL205 5.0 24.1 1.0

Iron binding site 8 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 3:Fe801 b:77.9 occ:1.00 FE2 3:SF4801 0.0 77.9 1.0 S3 3:SF4801 2.3 77.9 1.0 S4 3:SF4801 2.3 77.9 1.0 S1 3:SF4801 2.3 77.9 1.0 SG 3:CYS105 2.3 31.4 1.0 FE4 3:SF4801 2.7 77.9 1.0 FE3 3:SF4801 2.7 77.9 1.0 FE1 3:SF4801 2.7 77.9 1.0 CB 3:CYS105 3.3 11.7 1.0 CA 3:CYS105 3.5 11.9 1.0 NE2 3:GLN117 3.7 20.2 1.0 N 3:CYS105 3.8 17.1 1.0 S2 3:SF4801 3.9 77.9 1.0 CE 4:MET342 4.1 12.3 1.0 NE2 3:HIS101 4.1 49.1 1.0 CG 3:GLN117 4.1 20.3 1.0 CD 3:GLN117 4.3 20.2 1.0 CD2 3:HIS101 4.7 38.4 1.0 C 3:ASP104 4.7 15.0 1.0 SG 3:CYS108 4.8 17.0 1.0 SG 3:CYS114 4.9 27.6 1.0 C 3:CYS105 4.9 17.8 1.0 CB 3:CYS108 4.9 21.7 1.0 CG1 4:ILE346 5.0 20.5 1.0

Iron binding site 9 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 3:Fe801 b:77.9 occ:1.00 FE3 3:SF4801 0.0 77.9 1.0 NE2 3:HIS101 1.9 49.1 1.0 S2 3:SF4801 2.3 77.9 1.0 S1 3:SF4801 2.3 77.9 1.0 S4 3:SF4801 2.3 77.9 1.0 CE1 3:HIS101 2.7 61.7 1.0 FE2 3:SF4801 2.7 77.9 1.0 FE1 3:SF4801 2.7 77.9 1.0 FE4 3:SF4801 2.7 77.9 1.0 CD2 3:HIS101 3.0 38.4 1.0 ND1 3:HIS101 3.8 36.7 1.0 S3 3:SF4801 3.9 77.9 1.0 CG 3:HIS101 4.0 54.8 1.0 CD2 3:LEU116 4.3 20.2 1.0 CE 4:MET342 4.6 12.3 1.0 CG 3:ARG152 4.7 45.7 1.0 O 3:PRO102 4.7 19.4 1.0 SG 3:CYS105 4.8 31.4 1.0 CB 3:ARG152 4.8 36.0 1.0 SG 3:CYS114 4.8 27.6 1.0 SG 3:CYS108 4.8 17.0 1.0 CD 3:ARG152 4.9 63.9 1.0 N 3:GLY206 5.0 19.4 1.0 CB 3:VAL205 5.0 27.6 1.0

Iron binding site 10 out of 28 in the Deactive Complex I, OPEN2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Deactive Complex I, OPEN2 within 5.0Å range: probe atom residue distance (Å) B Occ 3:Fe801 b:77.9 occ:1.00 FE4 3:SF4801 0.0 77.9 1.0 S2 3:SF4801 2.3 77.9 1.0 S3 3:SF4801 2.3 77.9 1.0 S1 3:SF4801 2.3 77.9 1.0 SG 3:CYS108 2.3 17.0 1.0 FE2 3:SF4801 2.7 77.9 1.0 FE1 3:SF4801 2.7 77.9 1.0 FE3 3:SF4801 2.7 77.9 1.0 CB 3:CYS108 3.2 21.7 1.0 S4 3:SF4801 3.9 77.9 1.0 CB 3:GLN110 4.1 16.6 1.0 N 3:GLY206 4.3 19.4 1.0 CA 3:CYS105 4.4 11.9 1.0 CD 3:ARG152 4.5 63.9 1.0 CA 3:GLY206 4.5 15.2 1.0 NE2 3:HIS101 4.5 49.1 1.0 CA 3:CYS108 4.6 19.5 1.0 N 3:CYS105 4.7 17.1 1.0 SG 3:CYS105 4.7 31.4 1.0 N 3:GLY111 4.8 16.6 1.0 SG 3:CYS114 4.8 27.6 1.0 NE 3:ARG152 4.8 53.6 1.0 C 3:ASP104 4.9 15.0 1.0 CA 3:GLN110 4.9 18.4 1.0 O 3:ASP104 4.9 17.9 1.0 N 3:GLN110 4.9 16.9 1.0 C 3:GLN110 4.9 21.0 1.0 CG 3:GLN110 5.0 21.1 1.0

D.Kampjut, L.A.Sazanov. The Coupling Mechanism of Mammalian Respiratory Complex I. Science V. 370 2020.
ISSN: ESSN 1095-9203
PubMed: 32972993
DOI: 10.1126/SCIENCE.ABC4209