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Atomistry » Iron » PDB 7dyb-7ek5 » 7e7f | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 7dyb-7ek5 » 7e7f » |
Iron in PDB 7e7f: Human CYP11B1 Mutant in Complex with MetyraponeEnzymatic activity of Human CYP11B1 Mutant in Complex with Metyrapone
All present enzymatic activity of Human CYP11B1 Mutant in Complex with Metyrapone:
1.14.15.4; Protein crystallography data
The structure of Human CYP11B1 Mutant in Complex with Metyrapone, PDB code: 7e7f
was solved by
K.Mukai,
H.Sugimoto,
S.Reiko,
T.Matsuura,
T.Hishiki,
N.Kagawa,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Human CYP11B1 Mutant in Complex with Metyrapone
(pdb code 7e7f). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Human CYP11B1 Mutant in Complex with Metyrapone, PDB code: 7e7f: Iron binding site 1 out of 1 in 7e7fGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Human CYP11B1 Mutant in Complex with Metyrapone
![]() Mono view ![]() Stereo pair view
Reference:
K.Mukai,
H.Sugimoto,
K.Kamiya,
R.Suzuki,
T.Matsuura,
T.Hishiki,
H.Shimada,
Y.Shiro,
M.Suematsu,
N.Kagawa.
Spatially Restricted Substrate-Binding Site of Cortisol-Synthesizing CYP11B1 Limits Multiple Hydroxylations and Hinders Aldosterone Synthesis. Curr Res Struct Biol V. 3 192 2021.
Page generated: Wed Aug 6 22:11:03 2025
ISSN: ESSN 2665-928X PubMed: 34485929 DOI: 10.1016/J.CRSTBI.2021.08.001 |
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