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Atomistry » Iron » PDB 7ni3-7o4i » 7nqn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 7ni3-7o4i » 7nqn » |
Iron in PDB 7nqn: Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14Enzymatic activity of Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14
All present enzymatic activity of Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14:
1.14.19.70; Protein crystallography data
The structure of Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14, PDB code: 7nqn
was solved by
I.R.Selvam,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7nqn:
The structure of Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14 also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14
(pdb code 7nqn). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14, PDB code: 7nqn: Iron binding site 1 out of 1 in 7nqnGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Mycobacterium Tuberculosis Cytochrome P450 CYP121 in Complex with Lead Compound 14
![]() Mono view ![]() Stereo pair view
Reference:
M.Frederickson,
I.R.Selvam,
D.Evangelopoulos,
K.J.Mclean,
M.M.Katariya,
R.B.Tunnicliffe,
B.Campbell,
M.E.Kavanagh,
S.Charoensutthivarakul,
R.T.Blankley,
C.W.Levy,
L.P.S.De Carvalho,
D.Leys,
A.W.Munro,
A.G.Coyne,
C.Abell.
A New Strategy For Hit Generation: Novel in Cellulo Active Inhibitors of CYP121A1 From Mycobacterium Tuberculosis Via A Combined X-Ray Crystallographic and Phenotypic Screening Approach (Xp Screen). Eur.J.Med.Chem. V. 230 14105 2022.
Page generated: Thu Aug 8 09:50:35 2024
ISSN: ISSN 0223-5234 PubMed: 35065413 DOI: 10.1016/J.EJMECH.2022.114105 |
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