Atomistry » Iron » PDB 7ni3-7o4i » 7nw0
Atomistry »
  Iron »
    PDB 7ni3-7o4i »
      7nw0 »

Iron in PDB 7nw0: Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna

Enzymatic activity of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna

All present enzymatic activity of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna:
2.3.1.48; 2.7.7.6; 3.6.4.12;

Other elements in 7nw0:

The structure of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna also contains other interesting chemical elements:

Fluorine (F) 3 atoms
Zinc (Zn) 15 atoms
Magnesium (Mg) 2 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna (pdb code 7nw0). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna, PDB code: 7nw0:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 7nw0

Go back to Iron Binding Sites List in 7nw0
Iron binding site 1 out of 4 in the Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe1000

b:156.0
occ:1.00
FE1 0:SF41000 0.0 156.0 1.0
SG 0:CYS190 2.2 124.6 1.0
S4 0:SF41000 2.3 156.0 1.0
S3 0:SF41000 2.3 156.0 1.0
S2 0:SF41000 2.3 156.0 1.0
FE4 0:SF41000 2.7 156.0 1.0
FE3 0:SF41000 2.7 156.0 1.0
FE2 0:SF41000 2.7 156.0 1.0
CB 0:CYS190 3.6 124.6 1.0
S1 0:SF41000 3.9 156.0 1.0
CE2 0:PHE193 3.9 115.8 1.0
CD2 0:PHE193 4.0 115.8 1.0
CA 0:CYS190 4.3 124.6 1.0
CB 0:PHE157 4.6 116.5 1.0
SG 0:CYS155 4.6 114.1 1.0
CB 0:TYR158 4.7 118.2 1.0
SG 0:CYS134 4.8 118.3 1.0
N 0:TYR158 4.8 118.2 1.0
SG 0:CYS116 4.8 119.3 1.0

Iron binding site 2 out of 4 in 7nw0

Go back to Iron Binding Sites List in 7nw0
Iron binding site 2 out of 4 in the Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe1000

b:156.0
occ:1.00
FE2 0:SF41000 0.0 156.0 1.0
SG 0:CYS116 2.3 119.3 1.0
S3 0:SF41000 2.3 156.0 1.0
S1 0:SF41000 2.3 156.0 1.0
S4 0:SF41000 2.3 156.0 1.0
FE3 0:SF41000 2.7 156.0 1.0
FE4 0:SF41000 2.7 156.0 1.0
FE1 0:SF41000 2.7 156.0 1.0
CB 0:HIS118 3.8 104.8 1.0
CB 0:CYS116 3.9 119.3 1.0
S2 0:SF41000 3.9 156.0 1.0
N 0:HIS118 4.3 104.8 1.0
N 0:ILE117 4.5 110.8 1.0
CA 0:CYS116 4.6 119.3 1.0
CA 0:HIS118 4.7 104.8 1.0
SG 0:CYS134 4.7 118.3 1.0
CG2 0:VAL121 4.7 96.0 1.0
SG 0:CYS155 4.8 114.1 1.0
SG 0:CYS190 4.8 124.6 1.0
CG 0:HIS118 4.8 104.8 1.0

Iron binding site 3 out of 4 in 7nw0

Go back to Iron Binding Sites List in 7nw0
Iron binding site 3 out of 4 in the Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe1000

b:156.0
occ:1.00
FE3 0:SF41000 0.0 156.0 1.0
SG 0:CYS134 2.3 118.3 1.0
S2 0:SF41000 2.3 156.0 1.0
S1 0:SF41000 2.3 156.0 1.0
S4 0:SF41000 2.3 156.0 1.0
FE2 0:SF41000 2.7 156.0 1.0
FE1 0:SF41000 2.7 156.0 1.0
FE4 0:SF41000 2.7 156.0 1.0
CB 0:CYS134 3.4 118.3 1.0
S3 0:SF41000 3.9 156.0 1.0
CA 0:CYS134 4.1 118.3 1.0
CE2 0:PHE193 4.1 115.8 1.0
O 0:CYS134 4.7 118.3 1.0
SG 0:CYS116 4.7 119.3 1.0
SG 0:CYS190 4.8 124.6 1.0
C 0:CYS134 4.8 118.3 1.0
SG 0:CYS155 4.8 114.1 1.0
CZ 0:PHE193 4.8 115.8 1.0
CD2 0:PHE193 5.0 115.8 1.0

Iron binding site 4 out of 4 in 7nw0

Go back to Iron Binding Sites List in 7nw0
Iron binding site 4 out of 4 in the Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Rna Polymerase II Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe1000

b:156.0
occ:1.00
FE4 0:SF41000 0.0 156.0 1.0
SG 0:CYS155 2.2 114.1 1.0
S2 0:SF41000 2.3 156.0 1.0
S1 0:SF41000 2.3 156.0 1.0
S3 0:SF41000 2.3 156.0 1.0
FE1 0:SF41000 2.7 156.0 1.0
FE2 0:SF41000 2.7 156.0 1.0
FE3 0:SF41000 2.7 156.0 1.0
CB 0:CYS155 3.7 114.1 1.0
S4 0:SF41000 3.9 156.0 1.0
CB 0:HIS118 3.9 104.8 1.0
ND1 0:HIS118 4.0 104.8 1.0
CG 0:HIS118 4.1 104.8 1.0
CD2 0:PHE157 4.3 116.5 1.0
SG 0:CYS190 4.6 124.6 1.0
SG 0:CYS116 4.8 119.3 1.0
CB 0:PHE157 4.8 116.5 1.0
SG 0:CYS134 4.8 118.3 1.0
CE1 0:HIS118 4.8 104.8 1.0
CD2 0:HIS118 4.9 104.8 1.0
CA 0:CYS155 4.9 114.1 1.0

Reference:

S.Aibara, S.Schilbach, P.Cramer. Structures of Mammalian Rna Polymerase II Pre-Initiation Complexes. Nature 2021.
ISSN: ESSN 1476-4687
PubMed: 33902107
DOI: 10.1038/S41586-021-03554-8
Page generated: Thu Aug 8 09:54:02 2024

Last articles

Cl in 5UGH
Cl in 5UH0
Cl in 5UGR
Cl in 5UFU
Cl in 5UFR
Cl in 5UFQ
Cl in 5UFO
Cl in 5UFE
Cl in 5UEU
Cl in 5UF1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy