Iron in PDB 7o71: Cryo-Em Structure of A Respiratory Complex I

All present enzymatic activity of Cryo-Em Structure of A Respiratory Complex I:
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Cryo-Em Structure of A Respiratory Complex I also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Cryo-Em Structure of A Respiratory Complex I (pdb code 7o71). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Cryo-Em Structure of A Respiratory Complex I, PDB code: 7o71:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:21.6 occ:1.00 FE1 A:SF4801 0.0 21.6 1.0 S2 A:SF4801 2.3 21.6 1.0 S4 A:SF4801 2.3 21.6 1.0 S3 A:SF4801 2.3 21.6 1.0 SG A:CYS133 2.3 21.6 1.0 FE2 A:SF4801 2.7 21.6 1.0 FE4 A:SF4801 2.7 21.6 1.0 FE3 A:SF4801 2.7 21.6 1.0 CB A:CYS133 3.2 21.6 1.0 CA A:CYS133 3.4 21.6 1.0 NE2 A:GLN145 3.6 21.6 1.0 N A:CYS133 3.8 21.6 1.0 S1 A:SF4801 3.9 21.6 1.0 CG A:GLN145 4.0 21.6 1.0 CD A:GLN145 4.2 21.6 1.0 CE C:MET378 4.3 15.6 1.0 NE2 A:HIS129 4.7 21.6 1.0 C A:ASP132 4.7 14.8 1.0 CG1 C:ILE382 4.8 21.6 1.0 SG A:CYS142 4.8 21.6 1.0 C A:CYS133 4.8 21.6 1.0 SG A:CYS136 4.9 19.2 1.0 CB A:CYS136 4.9 19.2 1.0

Iron binding site 2 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:21.6 occ:1.00 FE2 A:SF4801 0.0 21.6 1.0 NE2 A:HIS129 2.1 21.6 1.0 S4 A:SF4801 2.3 21.6 1.0 S1 A:SF4801 2.3 21.6 1.0 S3 A:SF4801 2.3 21.6 1.0 FE1 A:SF4801 2.7 21.6 1.0 FE4 A:SF4801 2.7 21.6 1.0 FE3 A:SF4801 2.7 21.6 1.0 CD2 A:HIS129 3.0 21.6 1.0 CE1 A:HIS129 3.2 21.6 1.0 S2 A:SF4801 3.9 21.6 1.0 CG A:HIS129 4.2 21.6 1.0 CD2 A:LEU144 4.2 13.3 1.0 ND1 A:HIS129 4.2 21.6 1.0 CE C:MET378 4.6 15.6 1.0 O A:PRO130 4.6 13.3 1.0 SG A:CYS133 4.7 21.6 1.0 CG A:ARG182 4.7 15.2 1.0 SG A:CYS142 4.8 21.6 1.0 SG A:CYS136 4.8 19.2 1.0

Iron binding site 3 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:21.6 occ:1.00 FE3 A:SF4801 0.0 21.6 1.0 S1 A:SF4801 2.3 21.6 1.0 S4 A:SF4801 2.3 21.6 1.0 S2 A:SF4801 2.3 21.6 1.0 SG A:CYS136 2.3 19.2 1.0 FE2 A:SF4801 2.7 21.6 1.0 FE4 A:SF4801 2.7 21.6 1.0 FE1 A:SF4801 2.7 21.6 1.0 CB A:CYS136 3.1 19.2 1.0 S3 A:SF4801 3.9 21.6 1.0 CB A:GLN138 4.0 13.1 1.0 CA A:CYS133 4.5 21.6 1.0 N A:GLY236 4.5 10.7 1.0 CA A:CYS136 4.5 19.2 1.0 CD A:ARG182 4.5 15.2 1.0 N A:GLY139 4.6 12.3 1.0 NE2 A:HIS129 4.7 21.6 1.0 N A:CYS133 4.8 21.6 1.0 CA A:GLN138 4.8 13.1 1.0 N A:GLN138 4.8 13.1 1.0 SG A:CYS142 4.8 21.6 1.0 SG A:CYS133 4.8 21.6 1.0 NE A:ARG182 4.9 15.2 1.0 C A:GLN138 4.9 13.1 1.0 CA A:GLY236 4.9 10.7 1.0 CG A:ARG182 4.9 15.2 1.0 C A:CYS136 4.9 19.2 1.0 CG A:GLN138 4.9 13.1 1.0 C A:ASP132 5.0 14.8 1.0

Iron binding site 4 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:21.6 occ:1.00 FE4 A:SF4801 0.0 21.6 1.0 S2 A:SF4801 2.3 21.6 1.0 S3 A:SF4801 2.3 21.6 1.0 S1 A:SF4801 2.3 21.6 1.0 SG A:CYS142 2.3 21.6 1.0 FE2 A:SF4801 2.7 21.6 1.0 FE1 A:SF4801 2.7 21.6 1.0 FE3 A:SF4801 2.7 21.6 1.0 CB A:CYS142 3.3 21.6 1.0 CG A:GLN145 3.8 21.6 1.0 S4 A:SF4801 3.9 21.6 1.0 CB A:GLN138 4.4 13.1 1.0 CB A:LEU144 4.4 13.3 1.0 CD A:GLN145 4.4 21.6 1.0 N A:GLN145 4.4 21.6 1.0 CG A:GLN138 4.5 13.1 1.0 NE2 A:HIS129 4.5 21.6 1.0 CB A:GLN145 4.7 21.6 1.0 NE2 A:GLN145 4.7 21.6 1.0 CA A:CYS142 4.8 21.6 1.0 SG A:CYS136 4.8 19.2 1.0 SG A:CYS133 4.9 21.6 1.0 CD2 A:LEU144 4.9 13.3 1.0 CG1 A:VAL235 5.0 11.3 1.0

Iron binding site 5 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:11.7 occ:1.00 FE1 A:SF4802 0.0 11.7 1.0 S3 A:SF4802 2.3 11.7 1.0 S4 A:SF4802 2.3 11.7 1.0 S2 A:SF4802 2.3 11.7 1.0 SG A:CYS233 2.3 13.2 1.0 FE2 A:SF4802 2.7 11.7 1.0 FE4 A:SF4802 2.7 11.7 1.0 FE3 A:SF4802 2.7 11.7 1.0 CB A:CYS233 3.4 13.2 1.0 CA A:CYS233 3.8 13.2 1.0 S1 A:SF4802 3.9 11.7 1.0 CB A:ALA237 3.9 11.6 1.0 CD A:PRO234 4.1 11.9 1.0 CG2 A:VAL235 4.3 11.3 1.0 CD1 A:LEU238 4.4 11.6 1.0 CG A:LEU238 4.6 11.6 1.0 SG A:CYS186 4.6 12.4 1.0 C A:CYS233 4.6 13.2 1.0 N A:PRO234 4.7 11.9 1.0 SG A:CYS189 4.9 13.0 1.0 SG A:CYS183 4.9 13.4 1.0 CG A:PRO234 5.0 11.9 1.0 N A:CYS233 5.0 13.2 1.0

Iron binding site 6 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:11.7 occ:1.00 FE2 A:SF4802 0.0 11.7 1.0 S3 A:SF4802 2.3 11.7 1.0 S4 A:SF4802 2.3 11.7 1.0 S1 A:SF4802 2.3 11.7 1.0 SG A:CYS183 2.3 13.4 1.0 FE1 A:SF4802 2.7 11.7 1.0 FE3 A:SF4802 2.7 11.7 1.0 FE4 A:SF4802 2.7 11.7 1.0 CB A:CYS183 3.2 13.4 1.0 CA A:CYS183 3.7 13.4 1.0 N A:HIS185 3.8 9.6 1.0 S2 A:SF4802 3.9 11.7 1.0 N A:ILE184 4.0 7.4 1.0 CG1 A:ILE213 4.2 18.1 1.0 C A:CYS183 4.2 13.4 1.0 CA A:HIS185 4.3 9.6 1.0 N A:CYS186 4.5 12.4 1.0 CB A:ALA237 4.5 11.6 1.0 CB A:ILE213 4.8 18.1 1.0 C A:ILE184 4.8 7.4 1.0 SG A:CYS189 4.8 13.0 1.0 SG A:CYS233 4.8 13.2 1.0 CE A:MET180 4.9 13.4 1.0 C A:HIS185 4.9 9.6 1.0 SG A:CYS186 5.0 12.4 1.0

Iron binding site 7 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:11.7 occ:1.00 FE3 A:SF4802 0.0 11.7 1.0 S2 A:SF4802 2.3 11.7 1.0 S1 A:SF4802 2.3 11.7 1.0 S4 A:SF4802 2.3 11.7 1.0 SG A:CYS189 2.3 13.0 1.0 FE4 A:SF4802 2.7 11.7 1.0 FE1 A:SF4802 2.7 11.7 1.0 FE2 A:SF4802 2.7 11.7 1.0 CB A:CYS189 3.3 13.0 1.0 S3 A:SF4802 3.9 11.7 1.0 N A:CYS189 3.9 13.0 1.0 CD1 A:LEU238 4.2 11.6 1.0 CA A:CYS189 4.2 13.0 1.0 CG2 A:ILE213 4.3 18.1 1.0 CG1 A:ILE213 4.4 18.1 1.0 SG A:CYS186 4.7 12.4 1.0 N A:ARG188 4.7 10.4 1.0 SG A:CYS233 4.8 13.2 1.0 SG A:CYS183 4.8 13.4 1.0 CB A:ILE213 4.8 18.1 1.0 N A:THR187 4.8 10.8 1.0 CA A:THR187 4.9 10.8 1.0

Iron binding site 8 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:11.7 occ:1.00 FE4 A:SF4802 0.0 11.7 1.0 S1 A:SF4802 2.3 11.7 1.0 S3 A:SF4802 2.3 11.7 1.0 S2 A:SF4802 2.3 11.7 1.0 SG A:CYS186 2.3 12.4 1.0 FE3 A:SF4802 2.7 11.7 1.0 FE1 A:SF4802 2.7 11.7 1.0 FE2 A:SF4802 2.7 11.7 1.0 N A:CYS186 3.4 12.4 1.0 CB A:CYS186 3.5 12.4 1.0 N A:THR187 3.7 10.8 1.0 CA A:CYS186 3.8 12.4 1.0 S4 A:SF4802 3.9 11.7 1.0 CD A:PRO234 4.1 11.9 1.0 C A:CYS186 4.1 12.4 1.0 N A:ARG188 4.1 10.4 1.0 C A:HIS185 4.4 9.6 1.0 N A:HIS185 4.4 9.6 1.0 CA A:THR187 4.5 10.8 1.0 CG A:PRO234 4.7 11.9 1.0 CA A:HIS185 4.7 9.6 1.0 SG A:CYS189 4.7 13.0 1.0 SG A:CYS183 4.7 13.4 1.0 C A:THR187 4.8 10.8 1.0 SG A:CYS233 4.8 13.2 1.0 N A:CYS189 4.8 13.0 1.0 CB A:ARG188 4.8 10.4 1.0 CA A:ARG188 5.0 10.4 1.0

Iron binding site 9 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:18.5 occ:1.00 FE1 A:FES803 0.0 18.5 1.0 S1 A:FES803 2.2 18.5 1.0 S2 A:FES803 2.2 18.5 1.0 SG A:CYS69 2.3 10.3 1.0 SG A:CYS80 2.3 13.0 1.0 FE2 A:FES803 2.7 18.5 1.0 CB A:CYS80 3.3 13.0 1.0 N A:CYS80 3.4 13.0 1.0 CB A:CYS69 3.6 10.3 1.0 N A:CYS69 3.7 10.3 1.0 N A:ARG81 3.7 12.8 1.0 O A:HOH1008 3.8 11.8 1.0 CA A:CYS80 3.8 13.0 1.0 CA A:CYS69 4.1 10.3 1.0 C A:CYS80 4.2 13.0 1.0 N A:TYR70 4.2 13.2 1.0 SG A:CYS97 4.2 14.7 1.0 N A:ASN79 4.2 11.4 1.0 CA A:GLY78 4.3 13.4 1.0 C A:GLY78 4.4 13.4 1.0 N A:MET82 4.5 11.2 1.0 N A:TYR68 4.5 11.6 1.0 C A:CYS69 4.5 10.3 1.0 N A:GLY78 4.6 13.4 1.0 C A:ASN79 4.6 11.4 1.0 SG A:CYS83 4.7 12.4 1.0 CA A:ARG81 4.7 12.8 1.0 C A:TYR68 4.8 11.6 1.0

Iron binding site 10 out of 28 in the Cryo-Em Structure of A Respiratory Complex I


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Cryo-Em Structure of A Respiratory Complex I within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:18.5 occ:1.00 FE2 A:FES803 0.0 18.5 1.0 S2 A:FES803 2.2 18.5 1.0 S1 A:FES803 2.2 18.5 1.0 SG A:CYS83 2.3 12.4 1.0 SG A:CYS97 2.3 14.7 1.0 FE1 A:FES803 2.7 18.5 1.0 CB A:CYS97 3.2 14.7 1.0 CB A:CYS83 3.3 12.4 1.0 O A:HOH1008 4.0 11.8 1.0 N A:CYS97 4.1 14.7 1.0 CA A:CYS97 4.3 14.7 1.0 N A:CYS83 4.3 12.4 1.0 SG A:CYS69 4.3 10.3 1.0 CA A:CYS83 4.4 12.4 1.0 CA A:GLY78 4.4 13.4 1.0 SG A:CYS80 4.4 13.0 1.0 CB A:ALA95 4.6 15.2 1.0 CB A:TYR70 4.8 13.2 1.0 N A:ARG81 4.9 12.8 1.0 N A:SER96 5.0 15.4 1.0 N A:GLY78 5.0 13.4 1.0

K.Parey, J.Lasham, D.J.Mills, A.Djurabekova, O.Haapanen, E.Galemou Yoga, H.Xie, W.Kuhlbrandt, V.Sharma, J.Vonck, V.Zickermann. High-Resolution Structure and Dynamics of Mitochondrial Complex I - Insights Into the Proton Pumping Mechanism, Sci Adv 2021.
ISSN: ESSN 2375-2548