Iron in PDB 8avm: Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
Enzymatic activity of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
All present enzymatic activity of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis:
1.15.1.1;
Protein crystallography data
The structure of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis, PDB code: 8avm
was solved by
A.Basle,
A.Barwinska-Sendra,
K.M.Sendra,
K.Waldron,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
69.00 /
2.00
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
79.43,
117.11,
139.33,
90,
90,
90
|
|
R / Rfree (%)
|
19.3 /
22.9
|
Iron Binding Sites:
The binding sites of Iron atom in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
(pdb code 8avm). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 6 binding sites of Iron where determined in the
Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis, PDB code: 8avm:
Jump to Iron binding site number:
1;
2;
3;
4;
5;
6;
Iron binding site 1 out
of 6 in 8avm
Go back to
Iron Binding Sites List in 8avm
Iron binding site 1 out
of 6 in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
 Mono view
 Stereo pair view
|
|
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe201
b:29.1
occ:1.00
|
OD2
|
A:ASP158
|
1.9
|
28.3
|
1.0
|
|
O
|
A:HOH367
|
2.0
|
32.5
|
1.0
|
|
NE2
|
A:HIS162
|
2.1
|
23.1
|
1.0
|
|
NE2
|
A:HIS74
|
2.1
|
32.3
|
1.0
|
|
NE2
|
A:HIS26
|
2.2
|
28.7
|
1.0
|
|
CG
|
A:ASP158
|
3.0
|
30.6
|
1.0
|
|
CE1
|
A:HIS162
|
3.0
|
25.5
|
1.0
|
|
CD2
|
A:HIS162
|
3.0
|
29.3
|
1.0
|
|
CE1
|
A:HIS74
|
3.1
|
34.3
|
1.0
|
|
CD2
|
A:HIS74
|
3.1
|
31.4
|
1.0
|
|
CE1
|
A:HIS26
|
3.1
|
35.6
|
1.0
|
|
CD2
|
A:HIS26
|
3.2
|
28.6
|
1.0
|
|
HD2
|
A:HIS162
|
3.2
|
27.4
|
1.0
|
|
HE1
|
A:HIS162
|
3.2
|
26.1
|
1.0
|
|
HD2
|
A:HIS74
|
3.3
|
31.4
|
1.0
|
|
HE1
|
A:HIS74
|
3.3
|
33.2
|
1.0
|
|
HE1
|
A:HIS26
|
3.3
|
32.5
|
1.0
|
|
HD2
|
A:HIS26
|
3.3
|
29.9
|
1.0
|
|
OD1
|
A:ASP158
|
3.4
|
32.5
|
1.0
|
|
HB2
|
A:TRP160
|
3.5
|
30.5
|
1.0
|
|
HZ2
|
A:TRP124
|
3.5
|
30.2
|
1.0
|
|
HH2
|
A:TRP124
|
3.8
|
30.7
|
1.0
|
|
HB2
|
A:ALA163
|
3.9
|
31.2
|
1.0
|
|
CZ2
|
A:TRP124
|
4.0
|
31.8
|
1.0
|
|
CH2
|
A:TRP124
|
4.1
|
29.3
|
1.0
|
|
ND1
|
A:HIS162
|
4.2
|
30.5
|
1.0
|
|
ND1
|
A:HIS74
|
4.2
|
32.2
|
1.0
|
|
CG
|
A:HIS162
|
4.2
|
27.9
|
1.0
|
|
CG
|
A:HIS74
|
4.2
|
30.1
|
1.0
|
|
CB
|
A:ASP158
|
4.2
|
34.5
|
1.0
|
|
ND1
|
A:HIS26
|
4.3
|
30.5
|
1.0
|
|
CG
|
A:HIS26
|
4.3
|
33.8
|
1.0
|
|
HB2
|
A:ASP158
|
4.3
|
32.4
|
1.0
|
|
CB
|
A:TRP160
|
4.4
|
31.5
|
1.0
|
|
HB3
|
A:ASP158
|
4.5
|
32.4
|
1.0
|
|
HE2
|
A:TYR34
|
4.5
|
31.2
|
1.0
|
|
CG
|
A:TRP160
|
4.6
|
30.0
|
1.0
|
|
HB3
|
A:TRP160
|
4.6
|
30.5
|
1.0
|
|
NE2
|
A:GLN70
|
4.7
|
30.3
|
1.0
|
|
CB
|
A:ALA163
|
4.8
|
31.3
|
1.0
|
|
CD1
|
A:TRP160
|
4.8
|
29.8
|
1.0
|
|
HD1
|
A:TRP160
|
4.9
|
30.7
|
1.0
|
|
HA
|
A:ALA163
|
5.0
|
30.9
|
1.0
|
|
HB3
|
A:HIS30
|
5.0
|
29.5
|
1.0
|
|
Iron binding site 2 out
of 6 in 8avm
Go back to
Iron Binding Sites List in 8avm
Iron binding site 2 out
of 6 in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
 Mono view
 Stereo pair view
|
|
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Fe201
b:30.8
occ:1.00
|
OD2
|
B:ASP158
|
1.9
|
33.4
|
1.0
|
|
O
|
B:HOH357
|
2.0
|
30.1
|
1.0
|
|
NE2
|
B:HIS162
|
2.0
|
24.8
|
1.0
|
|
NE2
|
B:HIS74
|
2.1
|
33.9
|
1.0
|
|
NE2
|
B:HIS26
|
2.2
|
30.1
|
1.0
|
|
CG
|
B:ASP158
|
3.0
|
31.8
|
1.0
|
|
CD2
|
B:HIS162
|
3.0
|
32.2
|
1.0
|
|
CE1
|
B:HIS162
|
3.0
|
28.7
|
1.0
|
|
CE1
|
B:HIS74
|
3.1
|
33.2
|
1.0
|
|
CD2
|
B:HIS74
|
3.1
|
29.6
|
1.0
|
|
CE1
|
B:HIS26
|
3.1
|
36.6
|
1.0
|
|
CD2
|
B:HIS26
|
3.1
|
29.4
|
1.0
|
|
HD2
|
B:HIS162
|
3.2
|
30.2
|
1.0
|
|
HE1
|
B:HIS74
|
3.2
|
31.8
|
1.0
|
|
HE1
|
B:HIS162
|
3.2
|
27.9
|
1.0
|
|
HD2
|
B:HIS74
|
3.3
|
30.9
|
1.0
|
|
HE1
|
B:HIS26
|
3.3
|
32.7
|
1.0
|
|
HD2
|
B:HIS26
|
3.3
|
30.1
|
1.0
|
|
OD1
|
B:ASP158
|
3.4
|
29.1
|
1.0
|
|
HZ2
|
B:TRP124
|
3.6
|
29.3
|
1.0
|
|
HB2
|
B:TRP160
|
3.6
|
31.9
|
1.0
|
|
HH2
|
B:TRP124
|
3.8
|
28.5
|
1.0
|
|
HB2
|
B:ALA163
|
3.9
|
35.1
|
1.0
|
|
CZ2
|
B:TRP124
|
4.0
|
31.1
|
1.0
|
|
CH2
|
B:TRP124
|
4.1
|
27.9
|
1.0
|
|
CG
|
B:HIS162
|
4.2
|
31.6
|
1.0
|
|
ND1
|
B:HIS162
|
4.2
|
28.4
|
1.0
|
|
ND1
|
B:HIS74
|
4.2
|
27.2
|
1.0
|
|
CG
|
B:HIS74
|
4.2
|
31.3
|
1.0
|
|
ND1
|
B:HIS26
|
4.2
|
27.9
|
1.0
|
|
CB
|
B:ASP158
|
4.3
|
28.9
|
1.0
|
|
CG
|
B:HIS26
|
4.3
|
31.7
|
1.0
|
|
HB2
|
B:ASP158
|
4.3
|
30.7
|
1.0
|
|
CB
|
B:TRP160
|
4.4
|
32.7
|
1.0
|
|
HE2
|
B:TYR34
|
4.4
|
36.5
|
1.0
|
|
HB3
|
B:ASP158
|
4.5
|
30.7
|
1.0
|
|
HB3
|
B:TRP160
|
4.6
|
31.9
|
1.0
|
|
CG
|
B:TRP160
|
4.6
|
31.6
|
1.0
|
|
NE2
|
B:GLN70
|
4.6
|
26.7
|
1.0
|
|
CB
|
B:ALA163
|
4.8
|
36.4
|
1.0
|
|
CD1
|
B:TRP160
|
4.9
|
34.2
|
1.0
|
|
HA
|
B:ALA163
|
4.9
|
32.8
|
1.0
|
|
HB3
|
B:HIS30
|
4.9
|
32.2
|
1.0
|
|
HD1
|
B:TRP160
|
4.9
|
33.6
|
1.0
|
|
Iron binding site 3 out
of 6 in 8avm
Go back to
Iron Binding Sites List in 8avm
Iron binding site 3 out
of 6 in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
 Mono view
 Stereo pair view
|
|
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Fe201
b:30.1
occ:1.00
|
OD2
|
C:ASP158
|
1.9
|
30.3
|
1.0
|
|
O
|
C:HOH370
|
2.0
|
31.6
|
1.0
|
|
NE2
|
C:HIS74
|
2.1
|
32.7
|
1.0
|
|
NE2
|
C:HIS162
|
2.1
|
31.6
|
1.0
|
|
NE2
|
C:HIS26
|
2.2
|
29.6
|
1.0
|
|
CG
|
C:ASP158
|
3.0
|
33.3
|
1.0
|
|
CE1
|
C:HIS74
|
3.0
|
30.1
|
1.0
|
|
CD2
|
C:HIS74
|
3.1
|
30.8
|
1.0
|
|
CD2
|
C:HIS162
|
3.1
|
30.0
|
1.0
|
|
CE1
|
C:HIS162
|
3.1
|
31.9
|
1.0
|
|
CE1
|
C:HIS26
|
3.1
|
36.0
|
1.0
|
|
CD2
|
C:HIS26
|
3.2
|
27.8
|
1.0
|
|
HD2
|
C:HIS74
|
3.2
|
31.6
|
1.0
|
|
HD2
|
C:HIS162
|
3.2
|
31.3
|
1.0
|
|
HE1
|
C:HIS74
|
3.2
|
29.9
|
1.0
|
|
HE1
|
C:HIS26
|
3.3
|
32.4
|
1.0
|
|
HE1
|
C:HIS162
|
3.3
|
31.7
|
1.0
|
|
HD2
|
C:HIS26
|
3.3
|
28.6
|
1.0
|
|
OD1
|
C:ASP158
|
3.4
|
32.3
|
1.0
|
|
HZ2
|
C:TRP124
|
3.5
|
33.3
|
1.0
|
|
HB2
|
C:TRP160
|
3.6
|
31.4
|
1.0
|
|
HH2
|
C:TRP124
|
3.7
|
31.8
|
1.0
|
|
HB2
|
C:ALA163
|
3.9
|
34.1
|
1.0
|
|
CZ2
|
C:TRP124
|
3.9
|
34.8
|
1.0
|
|
CH2
|
C:TRP124
|
4.1
|
30.9
|
1.0
|
|
ND1
|
C:HIS74
|
4.1
|
27.0
|
1.0
|
|
CG
|
C:HIS74
|
4.2
|
33.3
|
1.0
|
|
ND1
|
C:HIS162
|
4.2
|
31.3
|
1.0
|
|
CG
|
C:HIS162
|
4.2
|
34.3
|
1.0
|
|
CB
|
C:ASP158
|
4.2
|
29.2
|
1.0
|
|
ND1
|
C:HIS26
|
4.2
|
28.6
|
1.0
|
|
CG
|
C:HIS26
|
4.3
|
28.7
|
1.0
|
|
HB2
|
C:ASP158
|
4.3
|
31.0
|
1.0
|
|
CB
|
C:TRP160
|
4.4
|
31.0
|
1.0
|
|
HB3
|
C:ASP158
|
4.4
|
31.0
|
1.0
|
|
HE2
|
C:TYR34
|
4.6
|
32.1
|
1.0
|
|
HB3
|
C:TRP160
|
4.6
|
31.4
|
1.0
|
|
CG
|
C:TRP160
|
4.6
|
33.7
|
1.0
|
|
NE2
|
C:GLN70
|
4.6
|
32.5
|
1.0
|
|
CB
|
C:ALA163
|
4.8
|
36.1
|
1.0
|
|
CD1
|
C:TRP160
|
4.9
|
29.3
|
1.0
|
|
HA
|
C:ALA163
|
4.9
|
30.7
|
1.0
|
|
HB3
|
C:HIS30
|
5.0
|
32.3
|
1.0
|
|
HD1
|
C:TRP160
|
5.0
|
30.8
|
1.0
|
|
CE2
|
C:TRP124
|
5.0
|
33.6
|
1.0
|
|
Iron binding site 4 out
of 6 in 8avm
Go back to
Iron Binding Sites List in 8avm
Iron binding site 4 out
of 6 in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
 Mono view
 Stereo pair view
|
|
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Fe201
b:31.7
occ:1.00
|
OD2
|
D:ASP158
|
1.9
|
31.9
|
1.0
|
|
O
|
D:HOH364
|
2.0
|
31.7
|
1.0
|
|
NE2
|
D:HIS74
|
2.0
|
35.4
|
1.0
|
|
NE2
|
D:HIS162
|
2.1
|
30.7
|
1.0
|
|
NE2
|
D:HIS26
|
2.2
|
31.9
|
1.0
|
|
CG
|
D:ASP158
|
3.0
|
34.1
|
1.0
|
|
CE1
|
D:HIS74
|
3.0
|
35.6
|
1.0
|
|
CD2
|
D:HIS74
|
3.0
|
36.1
|
1.0
|
|
CE1
|
D:HIS26
|
3.1
|
35.3
|
1.0
|
|
CD2
|
D:HIS162
|
3.1
|
32.3
|
1.0
|
|
CE1
|
D:HIS162
|
3.1
|
29.8
|
1.0
|
|
CD2
|
D:HIS26
|
3.2
|
37.0
|
1.0
|
|
HD2
|
D:HIS74
|
3.2
|
35.1
|
1.0
|
|
HE1
|
D:HIS74
|
3.2
|
35.7
|
1.0
|
|
HE1
|
D:HIS26
|
3.3
|
32.8
|
1.0
|
|
HD2
|
D:HIS162
|
3.3
|
31.9
|
1.0
|
|
HE1
|
D:HIS162
|
3.3
|
30.5
|
1.0
|
|
HD2
|
D:HIS26
|
3.4
|
33.5
|
1.0
|
|
OD1
|
D:ASP158
|
3.4
|
36.9
|
1.0
|
|
HZ2
|
D:TRP124
|
3.5
|
35.6
|
1.0
|
|
HB2
|
D:TRP160
|
3.6
|
31.4
|
1.0
|
|
HH2
|
D:TRP124
|
3.7
|
32.6
|
1.0
|
|
CZ2
|
D:TRP124
|
3.9
|
38.9
|
1.0
|
|
HB2
|
D:ALA163
|
3.9
|
36.1
|
1.0
|
|
CH2
|
D:TRP124
|
4.1
|
31.3
|
1.0
|
|
ND1
|
D:HIS74
|
4.1
|
36.6
|
1.0
|
|
CG
|
D:HIS74
|
4.2
|
32.8
|
1.0
|
|
CB
|
D:ASP158
|
4.2
|
33.3
|
1.0
|
|
ND1
|
D:HIS162
|
4.2
|
31.4
|
1.0
|
|
ND1
|
D:HIS26
|
4.3
|
28.7
|
1.0
|
|
CG
|
D:HIS162
|
4.3
|
32.5
|
1.0
|
|
CG
|
D:HIS26
|
4.3
|
28.2
|
1.0
|
|
HB2
|
D:ASP158
|
4.3
|
32.4
|
1.0
|
|
CB
|
D:TRP160
|
4.4
|
29.6
|
1.0
|
|
HB3
|
D:ASP158
|
4.5
|
32.4
|
1.0
|
|
HE2
|
D:TYR34
|
4.5
|
38.9
|
1.0
|
|
CG
|
D:TRP160
|
4.6
|
35.6
|
1.0
|
|
HB3
|
D:TRP160
|
4.6
|
31.4
|
1.0
|
|
NE2
|
D:GLN70
|
4.6
|
29.7
|
1.0
|
|
CB
|
D:ALA163
|
4.8
|
36.5
|
1.0
|
|
CD1
|
D:TRP160
|
4.9
|
34.0
|
1.0
|
|
HD1
|
D:TRP160
|
5.0
|
33.7
|
1.0
|
|
CE2
|
D:TRP124
|
5.0
|
34.7
|
1.0
|
|
HB3
|
D:HIS30
|
5.0
|
32.6
|
1.0
|
|
HA
|
D:ALA163
|
5.0
|
34.7
|
1.0
|
|
Iron binding site 5 out
of 6 in 8avm
Go back to
Iron Binding Sites List in 8avm
Iron binding site 5 out
of 6 in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
 Mono view
 Stereo pair view
|
|
A full contact list of Iron with other atoms in the Fe binding
site number 5 of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Fe201
b:33.4
occ:1.00
|
OD2
|
E:ASP158
|
1.9
|
33.2
|
1.0
|
|
O
|
E:HOH354
|
2.0
|
32.5
|
1.0
|
|
NE2
|
E:HIS74
|
2.1
|
37.6
|
1.0
|
|
NE2
|
E:HIS162
|
2.1
|
32.6
|
1.0
|
|
NE2
|
E:HIS26
|
2.2
|
30.6
|
1.0
|
|
CG
|
E:ASP158
|
3.0
|
31.9
|
1.0
|
|
CE1
|
E:HIS74
|
3.1
|
36.4
|
1.0
|
|
CD2
|
E:HIS74
|
3.1
|
34.0
|
1.0
|
|
CE1
|
E:HIS162
|
3.1
|
40.7
|
1.0
|
|
CD2
|
E:HIS162
|
3.1
|
29.9
|
1.0
|
|
CE1
|
E:HIS26
|
3.2
|
38.2
|
1.0
|
|
CD2
|
E:HIS26
|
3.2
|
32.3
|
1.0
|
|
HE1
|
E:HIS162
|
3.2
|
37.4
|
1.0
|
|
HD2
|
E:HIS74
|
3.2
|
34.7
|
1.0
|
|
HE1
|
E:HIS74
|
3.3
|
34.5
|
1.0
|
|
HD2
|
E:HIS162
|
3.3
|
31.9
|
1.0
|
|
HE1
|
E:HIS26
|
3.3
|
34.7
|
1.0
|
|
HD2
|
E:HIS26
|
3.4
|
32.1
|
1.0
|
|
OD1
|
E:ASP158
|
3.4
|
36.1
|
1.0
|
|
HZ2
|
E:TRP124
|
3.5
|
34.9
|
1.0
|
|
HB2
|
E:TRP160
|
3.6
|
34.7
|
1.0
|
|
HH2
|
E:TRP124
|
3.7
|
34.3
|
1.0
|
|
CZ2
|
E:TRP124
|
3.9
|
32.8
|
1.0
|
|
HB2
|
E:ALA163
|
3.9
|
32.6
|
1.0
|
|
CH2
|
E:TRP124
|
4.1
|
35.6
|
1.0
|
|
ND1
|
E:HIS74
|
4.2
|
28.2
|
1.0
|
|
CG
|
E:HIS74
|
4.2
|
34.0
|
1.0
|
|
ND1
|
E:HIS162
|
4.2
|
36.6
|
1.0
|
|
CB
|
E:ASP158
|
4.2
|
34.6
|
1.0
|
|
CG
|
E:HIS162
|
4.3
|
35.1
|
1.0
|
|
ND1
|
E:HIS26
|
4.3
|
32.2
|
1.0
|
|
HB2
|
E:ASP158
|
4.3
|
34.1
|
1.0
|
|
CG
|
E:HIS26
|
4.3
|
32.7
|
1.0
|
|
CB
|
E:TRP160
|
4.4
|
34.5
|
1.0
|
|
HB3
|
E:ASP158
|
4.5
|
34.1
|
1.0
|
|
HE2
|
E:TYR34
|
4.5
|
32.8
|
1.0
|
|
CG
|
E:TRP160
|
4.6
|
32.6
|
1.0
|
|
NE2
|
E:GLN70
|
4.6
|
33.2
|
1.0
|
|
HB3
|
E:TRP160
|
4.6
|
34.7
|
1.0
|
|
CD1
|
E:TRP160
|
4.8
|
32.3
|
1.0
|
|
CB
|
E:ALA163
|
4.9
|
31.7
|
1.0
|
|
HB3
|
E:HIS30
|
4.9
|
34.1
|
1.0
|
|
HD1
|
E:TRP160
|
4.9
|
33.5
|
1.0
|
|
CE2
|
E:TRP124
|
5.0
|
39.1
|
1.0
|
|
Iron binding site 6 out
of 6 in 8avm
Go back to
Iron Binding Sites List in 8avm
Iron binding site 6 out
of 6 in the Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis
 Mono view
 Stereo pair view
|
|
A full contact list of Iron with other atoms in the Fe binding
site number 6 of Mutant of Superoxide Dismutase SODFM2 From Bacteroides Fragilis within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Fe201
b:36.3
occ:1.00
|
O
|
F:HOH317
|
1.9
|
37.0
|
1.0
|
|
OD2
|
F:ASP158
|
1.9
|
33.7
|
1.0
|
|
NE2
|
F:HIS74
|
2.0
|
40.7
|
1.0
|
|
NE2
|
F:HIS26
|
2.1
|
31.2
|
1.0
|
|
NE2
|
F:HIS162
|
2.1
|
35.2
|
1.0
|
|
CD2
|
F:HIS74
|
3.0
|
38.7
|
1.0
|
|
CG
|
F:ASP158
|
3.0
|
35.8
|
1.0
|
|
CE1
|
F:HIS74
|
3.0
|
48.4
|
1.0
|
|
CD2
|
F:HIS162
|
3.1
|
38.0
|
1.0
|
|
CE1
|
F:HIS26
|
3.1
|
42.9
|
1.0
|
|
CE1
|
F:HIS162
|
3.1
|
33.5
|
1.0
|
|
CD2
|
F:HIS26
|
3.1
|
35.9
|
1.0
|
|
HD2
|
F:HIS74
|
3.2
|
39.9
|
1.0
|
|
HD2
|
F:HIS162
|
3.2
|
36.4
|
1.0
|
|
HE1
|
F:HIS74
|
3.2
|
43.7
|
1.0
|
|
HE1
|
F:HIS26
|
3.3
|
38.2
|
1.0
|
|
HD2
|
F:HIS26
|
3.3
|
34.7
|
1.0
|
|
HE1
|
F:HIS162
|
3.3
|
34.1
|
1.0
|
|
OD1
|
F:ASP158
|
3.5
|
33.6
|
1.0
|
|
HZ2
|
F:TRP124
|
3.6
|
39.5
|
1.0
|
|
HB2
|
F:TRP160
|
3.6
|
33.0
|
1.0
|
|
HH2
|
F:TRP124
|
3.8
|
40.2
|
1.0
|
|
HB2
|
F:ALA163
|
4.0
|
36.4
|
1.0
|
|
CZ2
|
F:TRP124
|
4.0
|
40.5
|
1.0
|
|
ND1
|
F:HIS74
|
4.1
|
37.8
|
1.0
|
|
CH2
|
F:TRP124
|
4.1
|
39.1
|
1.0
|
|
CG
|
F:HIS74
|
4.2
|
41.4
|
1.0
|
|
ND1
|
F:HIS26
|
4.2
|
36.5
|
1.0
|
|
CG
|
F:HIS26
|
4.2
|
34.7
|
1.0
|
|
ND1
|
F:HIS162
|
4.2
|
34.2
|
1.0
|
|
CG
|
F:HIS162
|
4.3
|
34.8
|
1.0
|
|
CB
|
F:ASP158
|
4.3
|
35.1
|
1.0
|
|
HB2
|
F:ASP158
|
4.4
|
35.4
|
1.0
|
|
HE2
|
F:TYR34
|
4.4
|
42.2
|
1.0
|
|
CB
|
F:TRP160
|
4.4
|
31.6
|
1.0
|
|
HB3
|
F:ASP158
|
4.5
|
35.3
|
1.0
|
|
NE2
|
F:GLN70
|
4.6
|
38.3
|
1.0
|
|
CG
|
F:TRP160
|
4.6
|
35.9
|
1.0
|
|
HB3
|
F:TRP160
|
4.7
|
33.0
|
1.0
|
|
CB
|
F:ALA163
|
4.9
|
36.0
|
1.0
|
|
HB3
|
F:HIS30
|
4.9
|
36.8
|
1.0
|
|
CD1
|
F:TRP160
|
4.9
|
36.1
|
1.0
|
|
HA
|
F:ALA163
|
5.0
|
34.9
|
1.0
|
|
HD1
|
F:TRP160
|
5.0
|
36.3
|
1.0
|
|
Reference:
K.M.Sendra,
A.Barwinska-Sendra,
E.S.Mackenzie,
A.Basle,
T.E.Kehl-Fie,
K.J.Waldron.
An Ancient Metalloenzyme Evolves Through Metal Preference Modulation. Nat Ecol Evol 2023.
ISSN: ISSN 2397-334X
PubMed: 37037909
DOI: 10.1038/S41559-023-02012-0
Page generated: Thu Aug 7 13:32:16 2025
|
