Iron in PDB 8c8q: Cytochrome C Oxidase From Schizosaccharomyces Pombe

All present enzymatic activity of Cytochrome C Oxidase From Schizosaccharomyces Pombe:
7.1.1.9;

The structure of Cytochrome C Oxidase From Schizosaccharomyces Pombe also contains other interesting chemical elements:

Calcium	(Ca)	1 atom
Zinc	(Zn)	1 atom
Copper	(Cu)	3 atoms
Magnesium	(Mg)	1 atom

The binding sites of Iron atom in the Cytochrome C Oxidase From Schizosaccharomyces Pombe (pdb code 8c8q). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Cytochrome C Oxidase From Schizosaccharomyces Pombe, PDB code: 8c8q:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Cytochrome C Oxidase From Schizosaccharomyces Pombe


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cytochrome C Oxidase From Schizosaccharomyces Pombe within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:65.6 occ:1.00 FE A:HEA601 0.0 65.6 1.0 NA A:HEA601 2.0 60.9 1.0 NE2 A:HIS385 2.0 47.6 1.0 NC A:HEA601 2.1 59.8 1.0 ND A:HEA601 2.1 59.1 1.0 NB A:HEA601 2.1 59.1 1.0 CE1 A:HIS385 2.6 44.9 1.0 NE2 A:HIS68 2.7 30.1 1.0 C4A A:HEA601 3.0 60.8 1.0 C1A A:HEA601 3.1 57.2 1.0 C4C A:HEA601 3.1 57.0 1.0 C1D A:HEA601 3.1 59.2 1.0 C1B A:HEA601 3.1 56.4 1.0 C1C A:HEA601 3.1 60.3 1.0 C4B A:HEA601 3.1 56.9 1.0 C4D A:HEA601 3.1 55.5 1.0 CD2 A:HIS385 3.3 36.1 1.0 CHB A:HEA601 3.5 64.6 1.0 CHD A:HEA601 3.5 58.0 1.0 CHC A:HEA601 3.5 61.0 1.0 CHA A:HEA601 3.5 58.8 1.0 CE1 A:HIS68 3.6 33.0 1.0 CD2 A:HIS68 3.6 19.2 1.0 ND1 A:HIS385 3.8 42.5 1.0 CG A:HIS385 4.2 28.9 1.0 C3A A:HEA601 4.3 55.4 1.0 C2A A:HEA601 4.3 53.4 1.0 C3C A:HEA601 4.4 55.9 1.0 C2D A:HEA601 4.5 58.5 1.0 C2B A:HEA601 4.5 54.0 1.0 C3D A:HEA601 4.5 54.9 1.0 C2C A:HEA601 4.5 60.1 1.0 C3B A:HEA601 4.5 51.3 1.0 ND1 A:HIS68 4.7 16.7 1.0 CG A:HIS68 4.8 11.9 1.0

Iron binding site 2 out of 2 in the Cytochrome C Oxidase From Schizosaccharomyces Pombe


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cytochrome C Oxidase From Schizosaccharomyces Pombe within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe602 b:54.4 occ:1.00 FE A:HEA602 0.0 54.4 1.0 NA A:HEA602 2.0 43.5 1.0 NC A:HEA602 2.1 39.7 1.0 ND A:HEA602 2.1 41.3 1.0 NB A:HEA602 2.1 44.9 1.0 NE2 A:HIS383 2.5 31.7 1.0 C4A A:HEA602 3.0 42.3 1.0 C1A A:HEA602 3.1 37.0 1.0 C4C A:HEA602 3.1 39.3 1.0 C1D A:HEA602 3.1 42.5 1.0 C1C A:HEA602 3.1 37.2 1.0 C4B A:HEA602 3.1 36.6 1.0 C1B A:HEA602 3.1 40.3 1.0 C4D A:HEA602 3.1 34.0 1.0 CE1 A:HIS383 3.3 31.9 1.0 CHD A:HEA602 3.5 40.9 1.0 CHB A:HEA602 3.5 40.1 1.0 CHC A:HEA602 3.5 31.9 1.0 CHA A:HEA602 3.5 31.4 1.0 CD2 A:HIS383 3.7 30.4 1.0 C3A A:HEA602 4.3 38.3 1.0 C2A A:HEA602 4.3 38.2 1.0 C3C A:HEA602 4.4 36.3 1.0 CU A:CU603 4.5 86.4 1.0 C2D A:HEA602 4.5 38.7 1.0 C2B A:HEA602 4.5 32.7 1.0 C3B A:HEA602 4.5 40.4 1.0 C3D A:HEA602 4.5 36.6 1.0 C2C A:HEA602 4.5 41.9 1.0 ND1 A:HIS383 4.5 33.3 1.0 CG A:HIS383 4.7 21.1 1.0

A.Moe, P.Adelroth, P.Brzezinski, L.Nasvik Ojemyr. Cryo-Em Structure and Function of S. Pombe Complex IV with Bound Respiratory Supercomplex Factor. Commun Chem V. 6 32 2023.
ISSN: ESSN 2399-3669
PubMed: 36797353
DOI: 10.1038/S42004-023-00827-3