Iron in PDB 8cat: The Nadph Binding Site on Beef Liver Catalase

All present enzymatic activity of The Nadph Binding Site on Beef Liver Catalase:
1.11.1.6;

The structure of The Nadph Binding Site on Beef Liver Catalase, PDB code: 8cat was solved by M.R.N.Murthy, T.J.Reid Iii, A.Sicignano, N.Tanaka, I.Fita, M.G.Rossmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.50 / 2.50
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	142.000, 142.000, 103.700, 90.00, 90.00, 120.00
R / Rfree (%)	19.1 / n/a

The binding sites of Iron atom in the The Nadph Binding Site on Beef Liver Catalase (pdb code 8cat). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the The Nadph Binding Site on Beef Liver Catalase, PDB code: 8cat:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the The Nadph Binding Site on Beef Liver Catalase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of The Nadph Binding Site on Beef Liver Catalase within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe507 b:21.1 occ:1.00 FE A:HEM507 0.0 21.1 1.0 OH A:TYR357 1.9 6.4 1.0 ND A:HEM507 2.0 20.8 1.0 NA A:HEM507 2.0 19.2 1.0 NB A:HEM507 2.0 19.1 1.0 NC A:HEM507 2.1 21.8 1.0 C1B A:HEM507 3.0 18.1 1.0 C4B A:HEM507 3.0 19.0 1.0 C1D A:HEM507 3.0 20.5 1.0 C4D A:HEM507 3.0 21.1 1.0 C4A A:HEM507 3.1 19.5 1.0 C4C A:HEM507 3.1 23.1 1.0 C1A A:HEM507 3.1 19.7 1.0 CZ A:TYR357 3.1 8.0 1.0 C1C A:HEM507 3.3 22.0 1.0 CHD A:HEM507 3.4 21.5 1.0 CHB A:HEM507 3.4 19.1 1.0 CHC A:HEM507 3.4 20.7 1.0 CHA A:HEM507 3.5 20.8 1.0 CE2 A:TYR357 4.0 8.4 1.0 NH2 A:ARG353 4.0 18.8 1.0 CE1 A:TYR357 4.0 8.2 1.0 C3B A:HEM507 4.2 17.8 1.0 C2B A:HEM507 4.2 17.4 1.0 C3D A:HEM507 4.3 20.4 1.0 C2D A:HEM507 4.3 20.9 1.0 C3A A:HEM507 4.3 19.4 1.0 C2A A:HEM507 4.3 18.9 1.0 C3C A:HEM507 4.4 23.0 1.0 C2C A:HEM507 4.5 22.5 1.0 CZ A:PHE160 4.5 10.7 1.0 NE A:ARG353 4.5 17.2 1.0 NE2 A:HIS74 4.8 20.9 1.0 CD2 A:HIS74 4.8 20.3 1.0 CZ A:ARG353 4.8 17.5 1.0 CG2 A:VAL73 4.9 14.0 1.0

Iron binding site 2 out of 2 in the The Nadph Binding Site on Beef Liver Catalase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of The Nadph Binding Site on Beef Liver Catalase within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe507 b:22.8 occ:1.00 FE B:HEM507 0.0 22.8 1.0 OH B:TYR357 1.9 14.4 1.0 ND B:HEM507 2.0 20.6 1.0 NA B:HEM507 2.0 20.9 1.0 NB B:HEM507 2.0 21.5 1.0 NC B:HEM507 2.1 22.7 1.0 C1B B:HEM507 3.0 21.2 1.0 C1A B:HEM507 3.0 20.8 1.0 C4D B:HEM507 3.0 20.2 1.0 C4B B:HEM507 3.0 21.7 1.0 C1D B:HEM507 3.0 20.5 1.0 C4A B:HEM507 3.1 20.2 1.0 C4C B:HEM507 3.1 23.8 1.0 CZ B:TYR357 3.1 13.3 1.0 C1C B:HEM507 3.3 23.4 1.0 CHB B:HEM507 3.4 21.0 1.0 CHD B:HEM507 3.4 21.6 1.0 CHC B:HEM507 3.4 22.2 1.0 CHA B:HEM507 3.4 19.6 1.0 CE1 B:TYR357 3.9 13.2 1.0 CE2 B:TYR357 4.0 12.7 1.0 NH2 B:ARG353 4.1 17.2 1.0 C2B B:HEM507 4.2 20.6 1.0 C3B B:HEM507 4.2 20.8 1.0 C2A B:HEM507 4.2 19.7 1.0 C3D B:HEM507 4.2 19.1 1.0 C2D B:HEM507 4.3 19.6 1.0 C3A B:HEM507 4.3 19.6 1.0 NE B:ARG353 4.3 16.7 1.0 C3C B:HEM507 4.4 23.4 1.0 C2C B:HEM507 4.4 23.1 1.0 NE2 B:HIS74 4.6 17.8 1.0 CZ B:PHE160 4.6 11.2 1.0 CD2 B:HIS74 4.6 18.1 1.0 CZ B:ARG353 4.7 16.8 1.0 CG2 B:VAL73 4.9 11.1 1.0

I.Fita, M.G.Rossmann. The Nadph Binding Site on Beef Liver Catalase. Proc.Natl.Acad.Sci.Usa V. 82 1604 1985.
ISSN: ISSN 0027-8424
PubMed: 3856839
DOI: 10.1073/PNAS.82.6.1604