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Atomistry » Iron » PDB 8cah-8csr » 8cjl » |
Iron in PDB 8cjl: Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004Enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004
All present enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004:
1.14.16.4; Protein crystallography data
The structure of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004, PDB code: 8cjl
was solved by
A.Schuetz,
K.Mallow,
M.Nazare,
E.Specker,
U.Heinemann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004
(pdb code 8cjl). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004, PDB code: 8cjl: Iron binding site 1 out of 1 in 8cjlGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Tpt-004
![]() Mono view ![]() Stereo pair view
Reference:
E.Specker,
R.Wesolowski,
A.Schutz,
S.Matthes,
K.Mallow,
M.Wasinska-Kalwa,
L.Winkler,
A.Oder,
N.Alenina,
D.Pleimes,
J.P.Von Kries,
U.Heinemann,
M.Bader,
M.Nazare.
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles As Highly Potent and in Vivo Efficacious Tryptophan Hydroxylase Inhibitors. J.Med.Chem. V. 66 14866 2023.
Page generated: Thu Aug 7 14:44:33 2025
ISSN: ISSN 0022-2623 PubMed: 37905925 DOI: 10.1021/ACS.JMEDCHEM.3C01454 |
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