Iron in PDB 8dvp: Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine

The structure of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine, PDB code: 8dvp was solved by M.Demir, L.P.Russelburg, M.P.Horvath, S.S.David, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	73.49 / 1.54
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	37.68, 86.17, 140.77, 90, 90, 90
R / Rfree (%)	21.7 / 23.3

The structure of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine also contains other interesting chemical elements:

Calcium

(Ca)

3 atoms

The binding sites of Iron atom in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine (pdb code 8dvp). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 8 binding sites of Iron where determined in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine, PDB code: 8dvp:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Iron binding site 1 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:34.2 occ:0.56 FE1 A:SF4401 0.0 34.2 0.6 FE2 A:SF4401 1.2 38.0 0.4 S4 A:SF4401 1.2 33.0 0.4 FE1 A:SF4401 1.8 33.3 0.4 S2 A:SF4401 2.2 30.5 0.6 SG A:CYS208 2.3 39.2 0.6 S3 A:SF4401 2.3 41.2 0.6 FE3 A:SF4401 2.3 31.4 0.4 S4 A:SF4401 2.3 28.9 0.6 S3 A:SF4401 2.4 37.1 0.4 FE3 A:SF4401 2.6 29.9 0.6 FE4 A:SF4401 2.7 37.2 0.6 FE2 A:SF4401 2.7 37.7 0.6 HB2 A:CYS208 2.9 40.2 0.4 S1 A:SF4401 3.0 37.3 0.4 FE4 A:SF4401 3.0 36.3 0.4 HB2 A:CYS208 3.0 40.2 0.6 SG A:CYS208 3.0 49.0 0.4 SG A:CYS205 3.1 41.1 0.4 HB3 A:CYS208 3.1 40.2 0.4 CB A:CYS208 3.1 50.4 0.4 CB A:CYS208 3.1 50.6 0.6 HB3 A:CYS208 3.3 40.2 0.6 S2 A:SF4401 3.4 31.2 0.4 HA A:CYS205 3.4 42.9 0.6 HA A:CYS205 3.4 42.9 0.4 HB2 A:CYS198 3.8 30.6 0.6 S1 A:SF4401 3.8 33.4 0.6 HG23 A:VAL210 3.9 44.3 1.0 HG11 A:VAL197 4.1 37.4 1.0 CA A:CYS205 4.3 49.8 0.4 HB3 A:CYS205 4.3 44.5 0.6 CA A:CYS205 4.3 49.9 0.6 HB2 A:CYS214 4.3 43.6 0.5 CB A:CYS205 4.3 52.3 0.4 SG A:CYS198 4.3 31.9 0.5 HB2 A:CYS214 4.4 43.6 0.5 HA A:GLN211 4.4 57.7 1.0 HB2 A:CYS198 4.5 30.6 0.5 HG12 A:VAL197 4.5 37.4 1.0 CB A:CYS198 4.6 34.0 0.6 CA A:CYS208 4.6 54.8 0.6 HA A:CYS198 4.6 32.3 0.5 HB3 A:CYS205 4.6 44.5 0.4 CB A:CYS205 4.6 53.0 0.6 CA A:CYS208 4.7 54.8 0.4 SG A:CYS198 4.7 29.5 0.6 SG A:CYS214 4.7 46.4 0.5 HA A:CYS198 4.7 32.3 0.6 CG2 A:VAL210 4.7 43.5 1.0 HG22 A:VAL210 4.8 44.3 1.0 SG A:CYS214 4.8 42.0 0.5 HA A:CYS208 4.8 44.3 0.6 CG1 A:VAL197 4.8 43.3 1.0 HD11 A:LEU193 4.8 39.7 1.0 SG A:CYS205 4.8 39.0 0.6 H A:VAL210 4.9 47.3 1.0 CB A:CYS198 4.9 34.8 0.5 CB A:CYS214 4.9 55.7 0.5 CB A:CYS214 4.9 55.7 0.5 HA A:CYS208 4.9 44.3 0.4 O A:CYS205 4.9 51.3 1.0

Iron binding site 2 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:33.3 occ:0.44 FE1 A:SF4401 0.0 33.3 0.4 SG A:CYS208 1.8 39.2 0.6 FE1 A:SF4401 1.8 34.2 0.6 HG23 A:VAL210 2.1 44.3 1.0 SG A:CYS208 2.2 49.0 0.4 S4 A:SF4401 2.2 33.0 0.4 S2 A:SF4401 2.3 31.2 0.4 S2 A:SF4401 2.3 30.5 0.6 S3 A:SF4401 2.3 37.1 0.4 FE3 A:SF4401 2.7 31.4 0.4 FE2 A:SF4401 2.7 38.0 0.4 FE4 A:SF4401 2.7 36.3 0.4 CG2 A:VAL210 2.9 43.5 1.0 HG22 A:VAL210 3.0 44.3 1.0 HG21 A:VAL210 3.3 44.3 1.0 CB A:CYS208 3.3 50.4 0.4 CB A:CYS208 3.4 50.6 0.6 H A:VAL210 3.4 47.3 1.0 HB2 A:CYS208 3.5 40.2 0.4 S3 A:SF4401 3.5 41.2 0.6 HB3 A:CYS208 3.5 40.2 0.4 FE4 A:SF4401 3.6 37.2 0.6 HB3 A:CYS208 3.6 40.2 0.6 HB2 A:CYS208 3.8 40.2 0.6 HD21 A:LEU193 3.8 35.7 1.0 S1 A:SF4401 3.8 37.3 0.4 FE3 A:SF4401 3.9 29.9 0.6 S4 A:SF4401 3.9 28.9 0.6 HD11 A:LEU193 4.0 39.7 1.0 C A:VAL210 4.0 52.8 1.0 HB2 A:CYS214 4.0 43.6 0.5 HB2 A:CYS214 4.0 43.6 0.5 O A:VAL210 4.1 50.6 1.0 CB A:VAL210 4.1 49.8 1.0 N A:VAL210 4.1 48.8 1.0 HD21 A:LEU154 4.2 42.0 1.0 HA A:GLN211 4.2 57.7 1.0 HB2 A:CYS198 4.2 30.6 0.6 CA A:VAL210 4.3 51.9 1.0 N A:GLN211 4.3 67.1 1.0 HG11 A:VAL197 4.4 37.4 1.0 HD23 A:LEU154 4.4 42.0 1.0 HB A:VAL210 4.4 48.3 1.0 FE2 A:SF4401 4.5 37.7 0.6 H A:GLN211 4.6 55.4 1.0 HD2 A:PRO209 4.6 47.8 1.0 CA A:CYS208 4.6 54.8 0.6 CA A:CYS208 4.7 54.8 0.4 SG A:CYS198 4.7 31.9 0.5 CD2 A:LEU193 4.7 44.0 1.0 HA A:CYS208 4.8 44.3 0.6 HB2 A:CYS198 4.8 30.6 0.5 CD2 A:LEU154 4.8 46.4 1.0 HA A:CYS205 4.8 42.9 0.4 CA A:GLN211 4.8 70.3 1.0 SG A:CYS205 4.8 41.1 0.4 HA A:CYS205 4.8 42.9 0.6 HG A:LEU193 4.8 37.6 1.0 CB A:CYS214 4.8 55.7 0.5 CB A:CYS214 4.9 55.7 0.5 CD1 A:LEU193 4.9 47.6 1.0 C A:CYS208 4.9 52.3 1.0 HA A:CYS208 4.9 44.3 0.4 SG A:CYS214 5.0 46.4 0.5 HG A:LEU154 5.0 40.3 1.0

Iron binding site 3 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:37.7 occ:0.56 FE2 A:SF4401 0.0 37.7 0.6 SG A:CYS205 1.0 41.1 0.4 FE2 A:SF4401 2.0 38.0 0.4 S1 A:SF4401 2.2 33.4 0.6 S4 A:SF4401 2.3 28.9 0.6 SG A:CYS205 2.3 39.0 0.6 S3 A:SF4401 2.3 41.2 0.6 FE3 A:SF4401 2.7 29.9 0.6 CB A:CYS205 2.7 52.3 0.4 FE4 A:SF4401 2.7 37.2 0.6 FE1 A:SF4401 2.7 34.2 0.6 HB3 A:CYS205 2.9 44.5 0.6 HA A:CYS205 2.9 42.9 0.6 S1 A:SF4401 2.9 37.3 0.4 CB A:CYS205 3.0 53.0 0.6 HA A:CYS205 3.1 42.9 0.4 HB2 A:CYS205 3.1 44.5 0.4 HB2 A:PRO203 3.2 36.2 1.0 S4 A:SF4401 3.2 33.0 0.4 HB3 A:CYS205 3.3 44.5 0.4 CA A:CYS205 3.4 49.9 0.6 CA A:CYS205 3.4 49.8 0.4 FE3 A:SF4401 3.8 31.4 0.4 HB2 A:PHE217 3.8 55.2 1.0 S2 A:SF4401 3.9 30.5 0.6 HB2 A:CYS205 3.9 44.5 0.6 N A:CYS205 3.9 45.3 1.0 H A:CYS205 4.0 39.8 0.6 H A:CYS205 4.0 39.8 0.4 HB1 A:ALA222 4.0 40.3 1.0 HB2 A:ALA222 4.0 40.3 1.0 S3 A:SF4401 4.0 37.1 0.4 CB A:PRO203 4.1 39.0 1.0 HG2 A:PRO203 4.1 31.2 1.0 HB2 A:CYS208 4.2 40.2 0.6 HB2 A:CYS208 4.3 40.2 0.4 FE4 A:SF4401 4.4 36.3 0.4 CB A:ALA222 4.4 42.7 1.0 HD1 A:PHE217 4.4 60.4 1.0 CG A:PRO203 4.5 34.7 1.0 HG3 A:PRO203 4.5 31.2 1.0 HB3 A:PRO203 4.5 36.2 1.0 FE1 A:SF4401 4.5 33.3 0.4 HD3 A:ARG153 4.6 23.3 1.0 HB3 A:ALA222 4.6 40.3 1.0 HB3 A:CYS208 4.6 40.2 0.4 HA A:CYS198 4.6 32.3 0.5 HA A:CYS198 4.6 32.3 0.6 SG A:CYS214 4.6 42.0 0.5 C A:CYS205 4.7 51.4 1.0 CB A:PHE217 4.8 57.3 1.0 HB3 A:CYS208 4.8 40.2 0.6 SG A:CYS208 4.8 39.2 0.6 SG A:CYS198 4.8 29.5 0.6 CB A:CYS208 4.8 50.6 0.6 C A:SER204 4.8 45.9 1.0 CD1 A:PHE217 4.9 62.4 1.0 SG A:CYS214 4.9 46.4 0.5 CB A:CYS208 4.9 50.4 0.4 HB2 A:CYS198 4.9 30.6 0.6 C A:PRO203 5.0 49.7 1.0 O A:PRO203 5.0 53.3 1.0

Iron binding site 4 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:38.0 occ:0.44 FE2 A:SF4401 0.0 38.0 0.4 FE1 A:SF4401 1.2 34.2 0.6 S3 A:SF4401 1.4 41.2 0.6 FE4 A:SF4401 1.8 37.2 0.6 FE2 A:SF4401 2.0 37.7 0.6 S1 A:SF4401 2.2 37.3 0.4 S3 A:SF4401 2.3 37.1 0.4 S4 A:SF4401 2.3 33.0 0.4 SG A:CYS205 2.3 41.1 0.4 S2 A:SF4401 2.4 30.5 0.6 FE3 A:SF4401 2.6 29.9 0.6 S4 A:SF4401 2.6 28.9 0.6 FE3 A:SF4401 2.7 31.4 0.4 FE4 A:SF4401 2.7 36.3 0.4 FE1 A:SF4401 2.7 33.3 0.4 S1 A:SF4401 3.0 33.4 0.6 HA A:CYS205 3.4 42.9 0.6 SG A:CYS208 3.4 39.2 0.6 HA A:CYS205 3.4 42.9 0.4 HB3 A:CYS205 3.6 44.5 0.6 HB2 A:CYS208 3.7 40.2 0.4 HB2 A:CYS208 3.7 40.2 0.6 HB3 A:CYS208 3.7 40.2 0.4 CB A:CYS205 3.8 52.3 0.4 HB2 A:CYS214 3.8 43.6 0.5 HB3 A:CYS208 3.8 40.2 0.6 S2 A:SF4401 3.8 31.2 0.4 SG A:CYS214 3.9 42.0 0.5 SG A:CYS214 3.9 46.4 0.5 HB2 A:CYS214 3.9 43.6 0.5 CB A:CYS208 3.9 50.6 0.6 CB A:CYS208 4.0 50.4 0.4 HB3 A:CYS205 4.0 44.5 0.4 HB2 A:PHE217 4.0 55.2 1.0 SG A:CYS208 4.0 49.0 0.4 CB A:CYS205 4.1 53.0 0.6 SG A:CYS205 4.1 39.0 0.6 CA A:CYS205 4.1 49.8 0.4 CA A:CYS205 4.1 49.9 0.6 CB A:CYS214 4.2 55.7 0.5 HB3 A:CYS214 4.2 43.6 0.5 CB A:CYS214 4.2 55.7 0.5 HB3 A:CYS214 4.2 43.6 0.5 HA A:GLN211 4.3 57.7 1.0 HB2 A:CYS205 4.5 44.5 0.4 HB2 A:CYS198 4.5 30.6 0.6 HG23 A:VAL210 4.6 44.3 1.0 SG A:CYS198 4.7 31.9 0.5 HB2 A:PRO203 4.8 36.2 1.0 SG A:CYS198 4.9 29.5 0.6 CB A:PHE217 4.9 57.3 1.0 O A:CYS205 5.0 51.3 1.0

Iron binding site 5 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:29.9 occ:0.56 FE3 A:SF4401 0.0 29.9 0.6 FE3 A:SF4401 1.7 31.4 0.4 S1 A:SF4401 2.1 37.3 0.4 S1 A:SF4401 2.2 33.4 0.6 S2 A:SF4401 2.3 30.5 0.6 S4 A:SF4401 2.3 28.9 0.6 SG A:CYS198 2.3 29.5 0.6 S4 A:SF4401 2.5 33.0 0.4 SG A:CYS198 2.5 31.9 0.5 FE2 A:SF4401 2.6 38.0 0.4 FE1 A:SF4401 2.6 34.2 0.6 FE2 A:SF4401 2.7 37.7 0.6 FE4 A:SF4401 2.7 37.2 0.6 HB2 A:CYS198 2.8 30.6 0.6 CB A:CYS198 3.0 34.0 0.6 HA A:CYS198 3.1 32.3 0.5 HD3 A:ARG153 3.1 23.3 1.0 HA A:CYS198 3.3 32.3 0.6 CB A:CYS198 3.5 34.8 0.5 HH11 A:ARG153 3.5 34.9 1.0 SG A:CYS205 3.6 41.1 0.4 HB2 A:CYS198 3.7 30.6 0.5 FE4 A:SF4401 3.7 36.3 0.4 CA A:CYS198 3.7 36.3 0.6 CA A:CYS198 3.8 36.1 0.5 HB2 A:PRO203 3.9 36.2 1.0 FE1 A:SF4401 3.9 33.3 0.4 S3 A:SF4401 3.9 41.2 0.6 HB3 A:CYS198 3.9 30.6 0.6 S2 A:SF4401 4.0 31.2 0.4 CD A:ARG153 4.0 26.9 1.0 HB3 A:ARG153 4.1 29.0 1.0 HD2 A:ARG153 4.1 23.3 1.0 NH1 A:ARG153 4.2 35.4 1.0 HB2 A:ARG153 4.3 29.0 1.0 HB3 A:CYS198 4.3 30.6 0.5 HB3 A:PRO203 4.3 36.2 1.0 CB A:PRO203 4.5 39.0 1.0 S3 A:SF4401 4.5 37.1 0.4 CB A:ARG153 4.6 33.9 1.0 HH12 A:ARG153 4.6 34.9 1.0 SG A:CYS208 4.7 39.2 0.6 HB1 A:ALA222 4.7 40.3 1.0 N A:CYS198 4.7 38.8 1.0 SG A:CYS214 4.7 46.4 0.5 HA A:VAL150 4.8 31.4 1.0 SG A:CYS214 4.8 42.0 0.5 C A:CYS198 4.8 32.1 1.0 HG3 A:PRO203 4.8 31.2 1.0 SG A:CYS205 4.8 39.0 0.6 HA A:CYS205 4.8 42.9 0.6 CG A:ARG153 4.9 40.9 1.0 HA A:CYS205 4.9 42.9 0.4 NE A:ARG153 4.9 40.9 1.0 HB2 A:CYS208 4.9 40.2 0.4 CZ A:ARG153 5.0 34.1 1.0

Iron binding site 6 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:31.4 occ:0.44 FE3 A:SF4401 0.0 31.4 0.4 S2 A:SF4401 0.9 30.5 0.6 FE3 A:SF4401 1.7 29.9 0.6 S4 A:SF4401 2.2 33.0 0.4 SG A:CYS198 2.3 31.9 0.5 S2 A:SF4401 2.3 31.2 0.4 S1 A:SF4401 2.3 37.3 0.4 FE1 A:SF4401 2.3 34.2 0.6 HB2 A:CYS198 2.6 30.6 0.6 FE1 A:SF4401 2.7 33.3 0.4 FE2 A:SF4401 2.7 38.0 0.4 FE4 A:SF4401 2.7 36.3 0.4 FE4 A:SF4401 2.8 37.2 0.6 SG A:CYS198 3.0 29.5 0.6 S4 A:SF4401 3.2 28.9 0.6 CB A:CYS198 3.2 34.0 0.6 HB2 A:CYS198 3.4 30.6 0.5 CB A:CYS198 3.5 34.8 0.5 S1 A:SF4401 3.5 33.4 0.6 FE2 A:SF4401 3.8 37.7 0.6 HB3 A:CYS198 3.8 30.6 0.6 S3 A:SF4401 3.9 37.1 0.4 SG A:CYS208 3.9 39.2 0.6 HA A:CYS198 4.0 32.3 0.5 S3 A:SF4401 4.0 41.2 0.6 HG13 A:VAL150 4.1 38.8 1.0 HG A:LEU154 4.2 40.3 1.0 HA A:CYS198 4.2 32.3 0.6 HB3 A:CYS198 4.2 30.6 0.5 HD3 A:ARG153 4.2 23.3 1.0 HA A:VAL150 4.3 31.4 1.0 HG23 A:VAL210 4.3 44.3 1.0 CA A:CYS198 4.3 36.1 0.5 CA A:CYS198 4.4 36.3 0.6 HB2 A:ARG153 4.4 29.0 1.0 HD21 A:LEU193 4.4 35.7 1.0 HG22 A:VAL150 4.4 31.5 1.0 SG A:CYS214 4.4 46.4 0.5 HB3 A:ARG153 4.4 29.0 1.0 SG A:CYS208 4.5 49.0 0.4 HD23 A:LEU154 4.5 42.0 1.0 SG A:CYS205 4.6 41.1 0.4 HB2 A:CYS214 4.6 43.6 0.5 HG A:LEU193 4.6 37.6 1.0 SG A:CYS214 4.7 42.0 0.5 HH11 A:ARG153 4.7 34.9 1.0 HB2 A:CYS214 4.8 43.6 0.5 HB2 A:CYS208 4.8 40.2 0.4 HD21 A:LEU154 4.8 42.0 1.0 HD2 A:ARG153 4.9 23.3 1.0 CB A:ARG153 4.9 33.9 1.0 HG21 A:VAL210 4.9 44.3 1.0 O A:VAL150 4.9 39.7 1.0 CG2 A:VAL210 5.0 43.5 1.0 CG1 A:VAL150 5.0 42.0 1.0 CD A:ARG153 5.0 26.9 1.0 CD2 A:LEU154 5.0 46.4 1.0 HD11 A:LEU193 5.0 39.7 1.0

Iron binding site 7 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:37.2 occ:0.56 FE4 A:SF4401 0.0 37.2 0.6 S1 A:SF4401 1.0 37.3 0.4 FE2 A:SF4401 1.8 38.0 0.4 FE4 A:SF4401 1.9 36.3 0.4 S2 A:SF4401 2.3 30.5 0.6 SG A:CYS214 2.3 42.0 0.5 SG A:CYS214 2.3 46.4 0.5 S1 A:SF4401 2.3 33.4 0.6 S3 A:SF4401 2.3 41.2 0.6 FE1 A:SF4401 2.7 34.2 0.6 FE3 A:SF4401 2.7 29.9 0.6 FE2 A:SF4401 2.7 37.7 0.6 FE3 A:SF4401 2.8 31.4 0.4 S3 A:SF4401 2.8 37.1 0.4 HB2 A:CYS214 2.9 43.6 0.5 HB2 A:CYS214 3.1 43.6 0.5 CB A:CYS214 3.1 55.7 0.5 CB A:CYS214 3.2 55.7 0.5 SG A:CYS205 3.2 41.1 0.4 HB3 A:CYS214 3.3 43.6 0.5 HB3 A:CYS214 3.4 43.6 0.5 HB2 A:PHE217 3.6 55.2 1.0 FE1 A:SF4401 3.6 33.3 0.4 S4 A:SF4401 3.6 33.0 0.4 HB3 A:ARG153 3.6 29.0 1.0 S2 A:SF4401 3.7 31.2 0.4 S4 A:SF4401 3.9 28.9 0.6 HD23 A:LEU154 4.1 42.0 1.0 H A:PHE217 4.2 49.8 1.0 HB3 A:ALA216 4.2 44.5 1.0 HD3 A:ARG153 4.3 23.3 1.0 CB A:PHE217 4.4 57.3 1.0 HB3 A:PHE217 4.5 55.2 1.0 CB A:ARG153 4.5 33.9 1.0 HB2 A:ALA222 4.5 40.3 1.0 CA A:CYS214 4.5 61.2 0.5 HB2 A:ARG153 4.5 29.0 1.0 CA A:CYS214 4.6 61.2 0.5 HB3 A:CYS205 4.6 44.5 0.6 HA A:CYS214 4.7 47.4 0.5 SG A:CYS198 4.7 31.9 0.5 HA A:CYS214 4.7 47.4 0.5 HA A:LEU154 4.7 40.0 1.0 SG A:CYS205 4.7 39.0 0.6 N A:PHE217 4.8 51.2 1.0 SG A:CYS208 4.8 39.2 0.6 SG A:CYS198 4.8 29.5 0.6 HG A:LEU154 4.8 40.3 1.0 CB A:CYS205 4.9 52.3 0.4 HB1 A:ALA222 4.9 40.3 1.0 HA A:CYS205 4.9 42.9 0.6 CD2 A:LEU154 5.0 46.4 1.0 HA A:GLN211 5.0 57.7 1.0

Iron binding site 8 out of 8 in the Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Glycosylase Muty Variant N146S in Complex with Dna Containing D(8-Oxo- G) Paired with Substrate Purine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:36.3 occ:0.44 FE4 A:SF4401 0.0 36.3 0.4 S2 A:SF4401 1.8 30.5 0.6 FE4 A:SF4401 1.9 37.2 0.6 HB2 A:CYS214 1.9 43.6 0.5 HB2 A:CYS214 2.1 43.6 0.5 S1 A:SF4401 2.2 37.3 0.4 S2 A:SF4401 2.3 31.2 0.4 S3 A:SF4401 2.3 37.1 0.4 SG A:CYS214 2.3 46.4 0.5 HD23 A:LEU154 2.4 42.0 1.0 CB A:CYS214 2.6 55.7 0.5 CB A:CYS214 2.6 55.7 0.5 FE2 A:SF4401 2.7 38.0 0.4 SG A:CYS214 2.7 42.0 0.5 FE1 A:SF4401 2.7 33.3 0.4 FE3 A:SF4401 2.7 31.4 0.4 FE1 A:SF4401 3.0 34.2 0.6 HB3 A:CYS214 3.2 43.6 0.5 CD2 A:LEU154 3.2 46.4 1.0 S3 A:SF4401 3.2 41.2 0.6 HB3 A:CYS214 3.2 43.6 0.5 HD21 A:LEU154 3.2 42.0 1.0 HG A:LEU154 3.5 40.3 1.0 HG23 A:VAL210 3.5 44.3 1.0 HA A:CYS214 3.6 47.4 0.5 FE3 A:SF4401 3.7 29.9 0.6 HA A:CYS214 3.7 47.4 0.5 CA A:CYS214 3.7 61.2 0.5 CA A:CYS214 3.8 61.2 0.5 HA A:LEU154 3.8 40.0 1.0 S4 A:SF4401 3.9 33.0 0.4 CG A:LEU154 3.9 42.8 1.0 HD22 A:LEU154 4.0 42.0 1.0 S1 A:SF4401 4.1 33.4 0.6 O A:VAL210 4.1 50.6 1.0 CG2 A:VAL210 4.4 43.5 1.0 FE2 A:SF4401 4.4 37.7 0.6 SG A:CYS208 4.4 39.2 0.6 HG21 A:VAL210 4.4 44.3 1.0 HB3 A:ARG153 4.4 29.0 1.0 N A:CYS214 4.5 64.3 1.0 CA A:LEU154 4.6 43.4 1.0 HA A:GLN211 4.6 57.7 1.0 H A:CYS214 4.6 48.7 0.5 H A:CYS214 4.6 48.7 0.5 SG A:CYS205 4.7 41.1 0.4 N A:LEU154 4.7 37.9 1.0 SG A:CYS208 4.8 49.0 0.4 C A:VAL210 4.8 52.8 1.0 HB2 A:PHE217 4.8 55.2 1.0 CB A:LEU154 4.8 44.2 1.0 SG A:CYS198 4.8 31.9 0.5 S4 A:SF4401 4.9 28.9 0.6 HD11 A:LEU154 4.9 46.7 1.0 HG22 A:VAL210 4.9 44.3 1.0 C A:CYS214 4.9 67.6 1.0 HB2 A:ARG153 4.9 29.0 1.0 H A:LEU154 4.9 36.3 1.0

M.Demir, L.P.Russelburg, J.Lin, C.H.Trasvina-Arenas, B.Huang, P.K.Yuen, M.P.Horvath, S.S.David. Structural Snapshots of Base Excision Mechanism By Dna Glycosylase Muty Reveal Retention of Stereochemistry For Abasic Site Product Formation To Be Published.