Iron in PDB 8ebw: Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2

All present enzymatic activity of Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2:
3.6.4.12;

The structure of Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2 also contains other interesting chemical elements:

Calcium	(Ca)	2 atoms
Zinc	(Zn)	5 atoms

The binding sites of Iron atom in the Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2 (pdb code 8ebw). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2, PDB code: 8ebw:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:398.0 occ:1.00 FE1 B:SF41000 0.0 398.0 1.0 SG B:CYS116 2.3 401.1 1.0 S4 B:SF41000 2.3 398.0 1.0 S3 B:SF41000 2.3 398.0 1.0 S2 B:SF41000 2.3 398.0 1.0 FE4 B:SF41000 2.7 398.0 1.0 FE2 B:SF41000 2.7 398.0 1.0 FE3 B:SF41000 2.7 398.0 1.0 CB B:CYS116 2.8 401.1 1.0 CA B:CYS116 3.3 401.1 1.0 N B:ILE117 3.7 374.6 1.0 N B:HIS118 3.9 377.8 1.0 S1 B:SF41000 3.9 398.0 1.0 C B:CYS116 3.9 401.1 1.0 CB B:HIS118 4.0 377.8 1.0 SG B:CYS190 4.5 379.5 1.0 CA B:HIS118 4.6 377.8 1.0 N B:CYS116 4.6 401.1 1.0 SG B:CYS155 4.6 362.8 1.0 SG B:CYS134 4.7 390.3 1.0 CB B:CYS134 4.8 390.3 1.0 C B:ILE117 4.8 374.6 1.0 CA B:ILE117 4.8 374.6 1.0 CG2 B:VAL121 4.8 375.5 1.0 CB B:VAL121 4.9 375.5 1.0

Iron binding site 2 out of 4 in the Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:398.0 occ:1.00 FE2 B:SF41000 0.0 398.0 1.0 SG B:CYS155 2.3 362.8 1.0 S1 B:SF41000 2.3 398.0 1.0 S4 B:SF41000 2.3 398.0 1.0 S3 B:SF41000 2.3 398.0 1.0 FE3 B:SF41000 2.7 398.0 1.0 FE1 B:SF41000 2.7 398.0 1.0 FE4 B:SF41000 2.7 398.0 1.0 CB B:CYS155 3.1 362.8 1.0 CB B:HIS118 3.7 377.8 1.0 S2 B:SF41000 3.9 398.0 1.0 CD1 B:PHE157 4.0 333.3 1.0 CG B:HIS118 4.3 377.8 1.0 CB B:PHE157 4.3 333.3 1.0 CA B:CYS155 4.4 362.8 1.0 CG B:PHE157 4.5 333.3 1.0 N B:HIS118 4.5 377.8 1.0 CD2 B:HIS118 4.6 377.8 1.0 SG B:CYS116 4.6 401.1 1.0 CA B:HIS118 4.6 377.8 1.0 SG B:CYS134 4.7 390.3 1.0 CE1 B:PHE157 4.8 333.3 1.0 CG2 B:THR138 5.0 398.7 1.0 SG B:CYS190 5.0 379.5 1.0

Iron binding site 3 out of 4 in the Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:398.0 occ:1.00 FE3 B:SF41000 0.0 398.0 1.0 SG B:CYS134 2.3 390.3 1.0 S2 B:SF41000 2.3 398.0 1.0 S4 B:SF41000 2.3 398.0 1.0 S1 B:SF41000 2.3 398.0 1.0 FE2 B:SF41000 2.7 398.0 1.0 FE4 B:SF41000 2.7 398.0 1.0 FE1 B:SF41000 2.7 398.0 1.0 CB B:CYS134 3.1 390.3 1.0 CE1 B:PHE193 3.7 352.1 1.0 CZ B:PHE193 3.8 352.1 1.0 S3 B:SF41000 3.9 398.0 1.0 CA B:CYS134 4.0 390.3 1.0 SG B:CYS155 4.3 362.8 1.0 SG B:CYS190 4.6 379.5 1.0 CD B:ARG112 4.6 361.0 1.0 CG2 B:THR138 4.7 398.7 1.0 C B:CYS134 4.7 390.3 1.0 NH1 B:ARG112 4.7 361.0 1.0 O B:CYS134 4.8 390.3 1.0 OG1 B:THR138 4.8 398.7 1.0 SG B:CYS116 4.8 401.1 1.0 CB B:CYS155 4.9 362.8 1.0 CD1 B:PHE193 5.0 352.1 1.0 CB B:CYS116 5.0 401.1 1.0

Iron binding site 4 out of 4 in the Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Initial Dna-Lesion (Ap) Binding By Xpc and Tfiih COMPLEX2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1000 b:398.0 occ:1.00 FE4 B:SF41000 0.0 398.0 1.0 SG B:CYS190 2.3 379.5 1.0 S1 B:SF41000 2.3 398.0 1.0 S2 B:SF41000 2.3 398.0 1.0 S3 B:SF41000 2.3 398.0 1.0 FE3 B:SF41000 2.7 398.0 1.0 FE1 B:SF41000 2.7 398.0 1.0 FE2 B:SF41000 2.7 398.0 1.0 CB B:CYS190 3.1 379.5 1.0 CE1 B:PHE193 3.5 352.1 1.0 S4 B:SF41000 3.9 398.0 1.0 CD1 B:PHE193 4.2 352.1 1.0 CB B:PHE157 4.2 333.3 1.0 CA B:CYS190 4.3 379.5 1.0 CA B:CYS116 4.4 401.1 1.0 N B:ILE117 4.5 374.6 1.0 CZ B:PHE193 4.5 352.1 1.0 O B:LEU115 4.6 389.8 1.0 CB B:CYS116 4.7 401.1 1.0 SG B:CYS116 4.8 401.1 1.0 SG B:CYS134 4.8 390.3 1.0 CG B:PHE157 4.9 333.3 1.0 N B:TYR158 5.0 313.5 1.0 SG B:CYS155 5.0 362.8 1.0

J.Kim, C.L.Li, X.Chen, Y.Cui, F.M.Golebiowski, H.Wang, F.Hanaoka, K.Sugasawa, W.Yang. Lesion Recognition By Xpc, Tfiih and Xpa in Dna Excision Repair Nature 2023.
ISSN: ESSN 1476-4687