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Atomistry » Iron » PDB 8f9j-8fhb » 8fgd » |
Iron in PDB 8fgd: Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-AmineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine, PDB code: 8fgd
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8fgd:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine
(pdb code 8fgd). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine, PDB code: 8fgd: Iron binding site 1 out of 1 in 8fgdGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-(5-(2-(Diethylamino)Ethyl)-2,3- Difluorophenethyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
D.Vasu,
H.T.Do,
H.Li,
C.D.Hardy,
A.Awasthi,
T.L.Poulos,
R.B.Silverman.
Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors. J.Med.Chem. V. 66 9934 2023.
Page generated: Sat Aug 10 03:43:23 2024
ISSN: ISSN 0022-2623 PubMed: 37433128 DOI: 10.1021/ACS.JMEDCHEM.3C00782 |
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