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Iron in PDB 8iuh: Rna Polymerase III Pre-Initiation Complex Open Complex 1

Enzymatic activity of Rna Polymerase III Pre-Initiation Complex Open Complex 1

All present enzymatic activity of Rna Polymerase III Pre-Initiation Complex Open Complex 1:
2.7.7.6;

Other elements in 8iuh:

The structure of Rna Polymerase III Pre-Initiation Complex Open Complex 1 also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Zinc (Zn) 8 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Rna Polymerase III Pre-Initiation Complex Open Complex 1 (pdb code 8iuh). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Rna Polymerase III Pre-Initiation Complex Open Complex 1, PDB code: 8iuh:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 8iuh

Go back to Iron Binding Sites List in 8iuh
Iron binding site 1 out of 4 in the Rna Polymerase III Pre-Initiation Complex Open Complex 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Rna Polymerase III Pre-Initiation Complex Open Complex 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:101.0
occ:1.00
FE1 P:SF4401 0.0 101.0 1.0
S3 P:SF4401 2.3 101.0 1.0
S2 P:SF4401 2.3 101.0 1.0
S4 P:SF4401 2.3 101.0 1.0
FE4 P:SF4401 2.7 101.0 1.0
FE3 P:SF4401 2.7 101.0 1.0
FE2 P:SF4401 2.7 101.0 1.0
SG P:CYS290 3.0 103.3 1.0
CB P:CYS290 3.4 103.3 1.0
S1 P:SF4401 3.9 101.0 1.0
CD2 P:TYR309 4.2 111.4 1.0
SG P:CYS307 4.2 108.3 1.0
CA P:CYS287 4.5 106.3 1.0
O P:PRO286 4.6 105.3 1.0
CE2 P:TYR309 4.7 111.4 1.0
CG P:TYR309 4.8 111.4 1.0
CA P:CYS290 4.9 103.3 1.0
CB P:TYR309 5.0 111.4 1.0

Iron binding site 2 out of 4 in 8iuh

Go back to Iron Binding Sites List in 8iuh
Iron binding site 2 out of 4 in the Rna Polymerase III Pre-Initiation Complex Open Complex 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Rna Polymerase III Pre-Initiation Complex Open Complex 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:101.0
occ:1.00
FE2 P:SF4401 0.0 101.0 1.0
S1 P:SF4401 2.3 101.0 1.0
S4 P:SF4401 2.3 101.0 1.0
S3 P:SF4401 2.3 101.0 1.0
FE3 P:SF4401 2.7 101.0 1.0
FE4 P:SF4401 2.7 101.0 1.0
FE1 P:SF4401 2.7 101.0 1.0
SG P:CYS296 3.4 104.5 1.0
CB P:CYS296 3.5 104.5 1.0
S2 P:SF4401 3.9 101.0 1.0
CA P:CYS296 4.3 104.5 1.0
CG2 P:ILE302 4.3 107.9 1.0
ND2 O:ASN445 4.4 104.9 1.0
SG P:CYS290 4.9 103.3 1.0

Iron binding site 3 out of 4 in 8iuh

Go back to Iron Binding Sites List in 8iuh
Iron binding site 3 out of 4 in the Rna Polymerase III Pre-Initiation Complex Open Complex 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Rna Polymerase III Pre-Initiation Complex Open Complex 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:101.0
occ:1.00
FE3 P:SF4401 0.0 101.0 1.0
S4 P:SF4401 2.3 101.0 1.0
S1 P:SF4401 2.3 101.0 1.0
S2 P:SF4401 2.3 101.0 1.0
FE2 P:SF4401 2.7 101.0 1.0
FE4 P:SF4401 2.7 101.0 1.0
FE1 P:SF4401 2.7 101.0 1.0
SG P:CYS287 3.1 106.3 1.0
CB P:CYS287 3.3 106.3 1.0
ND2 O:ASN445 3.5 104.9 1.0
CA P:CYS287 3.6 106.3 1.0
S3 P:SF4401 3.9 101.0 1.0
CG O:ASN445 4.2 104.9 1.0
CB O:ASN445 4.2 104.9 1.0
N P:CYS287 4.4 106.3 1.0
C P:CYS287 4.7 106.3 1.0
SG P:CYS296 4.8 104.5 1.0
O P:CYS287 4.8 106.3 1.0
CD1 P:PHE293 4.9 103.6 1.0

Iron binding site 4 out of 4 in 8iuh

Go back to Iron Binding Sites List in 8iuh
Iron binding site 4 out of 4 in the Rna Polymerase III Pre-Initiation Complex Open Complex 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Rna Polymerase III Pre-Initiation Complex Open Complex 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:101.0
occ:1.00
FE4 P:SF4401 0.0 101.0 1.0
S1 P:SF4401 2.3 101.0 1.0
S3 P:SF4401 2.3 101.0 1.0
S2 P:SF4401 2.3 101.0 1.0
FE1 P:SF4401 2.7 101.0 1.0
FE3 P:SF4401 2.7 101.0 1.0
FE2 P:SF4401 2.7 101.0 1.0
SG P:CYS307 3.1 108.3 1.0
CB P:CYS307 3.4 108.3 1.0
CE P:MET310 3.6 117.8 1.0
S4 P:SF4401 3.9 101.0 1.0
CA P:PRO304 4.1 105.5 1.0
SD P:MET310 4.5 117.8 1.0
CB P:PRO304 4.5 105.5 1.0
N P:PRO304 4.6 105.5 1.0
CG P:MET310 4.6 117.8 1.0
O P:SER303 4.7 107.8 1.0
CA P:CYS307 4.7 108.3 1.0
C P:SER303 4.9 107.8 1.0
SG P:CYS287 4.9 106.3 1.0

Reference:

H.Hou, Q.Jin, Y.Ren, Z.Chen, Q.Wang, Y.Xu. Structure of the Snapc-Bound Rna Polymerase III Preinitiation Complex. Cell Res. 2023.
ISSN: ISSN 1001-0602
PubMed: 37165065
DOI: 10.1038/S41422-023-00819-X
Page generated: Sat Aug 10 06:25:09 2024

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