Iron in PDB 8j9l: Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2

All present enzymatic activity of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2:
1.16.3.1;

The structure of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2, PDB code: 8j9l was solved by X.Chen, G.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.26 / 2.50
Space group	H 3 2 2
Cell size a, b, c (Å), α, β, γ (°)	261.696, 261.696, 320.511, 90, 90, 120
R / Rfree (%)	24.7 / 28.9

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 16;

Binding sites:

The binding sites of Iron atom in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 (pdb code 8j9l). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 16 binding sites of Iron where determined in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2, PDB code: 8j9l:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe201 b:49.3 occ:1.00 ND1 A:HIS65 2.2 30.6 1.0 OE2 A:GLU27 2.2 30.0 1.0 OE1 A:GLU62 2.4 26.2 1.0 CE1 A:HIS65 2.9 29.1 1.0 CD A:GLU27 3.0 28.6 1.0 OE1 A:GLU27 3.2 38.1 1.0 OE1 A:GLN141 3.4 33.5 1.0 CG A:HIS65 3.4 27.5 1.0 CD A:GLU62 3.4 32.4 1.0 OE2 A:GLU62 3.7 35.4 1.0 CB A:HIS65 3.9 20.4 1.0 NE2 A:HIS65 4.1 28.0 1.0 CG1 A:VAL110 4.2 13.7 1.0 CD A:GLN141 4.4 20.6 1.0 CD2 A:HIS65 4.4 27.5 1.0 CG A:GLU27 4.5 19.1 1.0 CG A:GLU62 4.8 23.1 1.0 OE1 A:GLU107 4.8 34.9 1.0 NE2 A:GLN141 4.9 19.9 1.0 CD2 A:TYR137 4.9 19.5 1.0 CA A:GLU62 4.9 18.6 1.0

Iron binding site 2 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:49.1 occ:0.50 CE1 K:HIS173 3.0 16.6 1.0 CE1 B:HIS173 3.0 26.6 1.0 NE2 K:HIS173 3.6 29.6 1.0 NE2 B:HIS173 3.7 32.8 1.0 ND1 B:HIS173 4.0 28.9 1.0 ND1 K:HIS173 4.0 15.9 1.0 CD2 K:LEU169 4.2 10.8 1.0 CD2 B:LEU169 4.2 13.1 1.0 CD1 B:LEU169 4.8 16.6 1.0 CD2 K:HIS173 4.9 21.0 1.0 CD2 B:HIS173 5.0 28.8 1.0

Iron binding site 3 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe202 b:49.2 occ:1.00 OE2 B:GLU27 2.4 21.2 1.0 ND1 B:HIS65 2.5 26.5 1.0 OE1 B:GLU62 2.6 38.4 1.0 CE1 B:HIS65 3.1 27.9 1.0 OE1 B:GLU27 3.1 18.9 1.0 CD B:GLU27 3.1 21.0 1.0 CG B:HIS65 3.3 25.4 1.0 CD B:GLU62 3.5 43.3 1.0 NE2 B:GLN141 3.6 30.2 1.0 OE2 B:GLU62 3.7 36.9 1.0 CB B:HIS65 3.8 18.4 1.0 NE2 B:HIS65 4.0 34.9 1.0 CD2 B:HIS65 4.1 32.0 1.0 CG1 B:VAL110 4.2 9.3 1.0 CD B:GLN141 4.4 15.9 1.0 CG B:GLU27 4.6 21.0 1.0 OE1 B:GLN141 4.7 17.4 1.0 CD2 B:TYR137 4.8 14.2 1.0 CE2 B:TYR137 4.8 20.9 1.0 CG B:GLU62 4.9 29.4 1.0

Iron binding site 4 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe201 b:44.5 occ:1.00 CE1 I:HIS173 3.0 21.7 1.0 CE1 C:HIS173 3.1 18.6 1.0 NE2 I:HIS173 3.6 18.1 1.0 NE2 C:HIS173 3.7 20.7 1.0 ND1 I:HIS173 4.1 23.7 1.0 CD2 I:LEU169 4.1 12.3 1.0 ND1 C:HIS173 4.3 25.1 1.0 CD2 C:LEU169 4.3 12.9 1.0 CD1 I:LEU169 4.7 9.0 1.0 CD1 C:LEU169 4.8 12.3 1.0 CD2 I:HIS173 4.8 12.3 1.0 CD2 C:HIS173 5.0 14.9 1.0 CG I:LEU169 5.0 10.9 1.0

Iron binding site 5 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe202 b:55.6 occ:1.00 OE1 C:GLU62 2.2 22.0 1.0 ND1 C:HIS65 2.4 24.8 1.0 OE2 C:GLU27 2.4 23.1 1.0 CD C:GLU62 2.9 25.5 1.0 OE2 C:GLU62 2.9 42.6 1.0 CE1 C:HIS65 3.2 29.4 1.0 CD C:GLU27 3.2 21.2 1.0 OE1 C:GLU27 3.2 21.4 1.0 OE1 C:GLN141 3.5 32.1 1.0 CG C:HIS65 3.5 17.3 1.0 CG1 C:VAL110 3.8 14.7 1.0 CB C:HIS65 3.9 17.1 1.0 CD C:GLN141 4.3 23.6 1.0 NE2 C:HIS65 4.4 35.0 1.0 CG C:GLU62 4.4 14.9 1.0 CD2 C:HIS65 4.6 21.0 1.0 CG C:GLU27 4.6 14.8 1.0 NE2 C:GLN141 4.7 22.6 1.0 OE1 C:GLU107 4.7 38.4 1.0 CB C:VAL110 4.9 14.0 1.0 CA C:GLU62 4.9 22.3 1.0 CD1 C:TYR137 4.9 21.9 1.0

Iron binding site 6 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe201 b:42.4 occ:1.00 OE2 D:GLU27 2.3 21.6 1.0 OE1 D:GLU62 2.3 38.6 1.0 ND1 D:HIS65 2.6 24.9 1.0 OE1 D:GLU27 3.0 18.8 1.0 CD D:GLU27 3.0 22.8 1.0 CD D:GLU62 3.3 32.9 1.0 OE1 D:GLN141 3.3 30.4 1.0 CE1 D:HIS65 3.4 28.8 1.0 OE2 D:GLU62 3.5 37.1 1.0 CG D:HIS65 3.6 23.7 1.0 CB D:HIS65 4.0 16.8 1.0 CG1 D:VAL110 4.3 8.7 1.0 CG D:GLU27 4.4 15.5 1.0 CD D:GLN141 4.5 16.0 1.0 NE2 D:HIS65 4.5 38.8 1.0 CD2 D:HIS65 4.6 22.5 1.0 CG D:GLU62 4.7 25.1 1.0 OE1 D:GLU107 4.8 32.4 1.0 CA D:GLU62 4.9 22.8 1.0

Iron binding site 7 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe202 b:51.0 occ:0.50 CE1 L:HIS173 3.0 20.0 1.0 CE1 D:HIS173 3.1 22.3 1.0 CD2 L:LEU169 3.7 8.4 1.0 NE2 L:HIS173 3.8 21.4 1.0 NE2 D:HIS173 3.8 27.3 1.0 ND1 L:HIS173 4.0 19.3 1.0 ND1 D:HIS173 4.2 24.6 1.0 CD2 D:LEU169 4.4 9.7 1.0 CD1 D:LEU169 4.8 11.5 1.0 CG L:LEU169 4.9 13.2 1.0 CD1 L:LEU169 4.9 7.5 1.0 CD2 L:HIS173 5.0 16.4 1.0

Iron binding site 8 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe201 b:43.1 occ:1.00 OE2 E:GLU62 2.2 36.1 1.0 OE2 E:GLU27 2.3 20.1 1.0 ND1 E:HIS65 2.3 31.0 1.0 CE1 E:HIS65 3.0 27.4 1.0 CD E:GLU62 3.2 25.1 1.0 CD E:GLU27 3.3 26.1 1.0 OE1 E:GLU62 3.4 27.8 1.0 CG E:HIS65 3.5 29.7 1.0 OE1 E:GLU27 3.5 31.1 1.0 OE1 E:GLN141 3.5 29.4 1.0 CB E:HIS65 3.9 22.2 1.0 CG1 E:VAL110 4.0 9.9 1.0 NE2 E:HIS65 4.2 35.9 1.0 CD2 E:HIS65 4.5 34.5 1.0 CG E:GLU62 4.6 21.9 1.0 CD E:GLN141 4.6 21.1 1.0 CG E:GLU27 4.7 21.7 1.0 OE1 E:GLU107 4.9 38.0 1.0 CB E:GLU62 4.9 19.7 1.0 CA E:GLU62 5.0 19.7 1.0

Iron binding site 9 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe201 b:53.0 occ:1.00 OE2 F:GLU62 2.2 28.4 1.0 OE2 F:GLU27 2.5 30.3 1.0 ND1 F:HIS65 2.6 30.4 1.0 CD F:GLU62 3.0 31.5 1.0 OE1 F:GLU62 3.1 38.6 1.0 CE1 F:HIS65 3.2 27.3 1.0 OE1 F:GLN141 3.4 25.1 1.0 CG F:HIS65 3.4 30.4 1.0 CD F:GLU27 3.4 32.6 1.0 OE1 F:GLU27 3.7 34.0 1.0 CB F:HIS65 3.9 19.9 1.0 CG1 F:VAL110 4.2 17.2 1.0 NE2 F:HIS65 4.2 35.7 1.0 CD F:GLN141 4.3 22.4 1.0 CD2 F:HIS65 4.3 27.2 1.0 CG F:GLU62 4.5 26.1 1.0 OE1 F:GLU107 4.6 42.0 1.0 CD1 F:TYR137 4.7 17.8 1.0 CG F:GLU27 4.9 21.9 1.0 CE1 F:TYR137 4.9 20.7 1.0 CA F:GLU62 4.9 23.7 1.0

Iron binding site 10 out of 16 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in SOLUTION2 within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe201 b:43.1 occ:1.00 OE1 G:GLU62 2.2 19.7 1.0 OE2 G:GLU27 2.4 33.1 1.0 ND1 G:HIS65 2.6 25.2 1.0 CD G:GLU62 3.1 29.1 1.0 OE2 G:GLU62 3.3 38.5 1.0 OE1 G:GLN141 3.3 29.4 1.0 CD G:GLU27 3.3 21.4 1.0 CE1 G:HIS65 3.3 34.6 1.0 OE1 G:GLU27 3.5 16.6 1.0 CG G:HIS65 3.6 33.1 1.0 CB G:HIS65 3.9 22.1 1.0 CG1 G:VAL110 4.2 9.1 1.0 NE2 G:HIS65 4.4 48.1 1.0 CD G:GLN141 4.5 23.0 1.0 CD2 G:HIS65 4.5 30.3 1.0 CG G:GLU62 4.6 29.6 1.0 OE1 G:GLU107 4.7 40.0 1.0 CG G:GLU27 4.7 13.8 1.0 CD2 G:TYR137 4.8 17.2 1.0 CA G:GLU62 4.9 20.1 1.0

X.Chen, T.Zhang, H.Liu, J.Zang, C.Lv, M.Du, G.Zhao. Shape-Anisotropic Assembly of Protein Nanocages with Identical Building Blocks By Designed Intermolecular Pi-Pi Interactions. Adv Sci V. 10 05398 2023.
ISSN: ESSN 2198-3844
PubMed: 37870198
DOI: 10.1002/ADVS.202305398